Home Tools
Log in
Cart

5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.
Cat No. product name
T41143 PCPA methyl ester hydrochloride pCPA methyl ester hydrochloride 是色氨酸羟化酶抑制剂和5-HT合成的抑制剂。 pCPA methyl ester hydrochloride 可穿过血脑屏障并降低 5-HT 中枢可用性。
T1644 Dopamine hydrochloride Dopamine is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine b...
T0802 Procaine hydrochloride Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds ...
T1540 Doxepin hydrochloride Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mech...
T0678 Amitriptyline hydrochloride Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
T1077 Fluvoxamine maleate Fluvoxamine maleate is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
T0074 Chlorprothixene Chlorprothixene is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.
T2631 WAY-100635 Maleate WAY-100635 is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).
T8385 Metoclopramide hydrochloride hydrate Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic
T7521 Azaphen Azaphen is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
T12865 SCH-23390 maleate SCH-23390 maleate is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, respectively).
T35841 5-Benzyloxygramine 5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabili...
T1539 Iloperidone Iloperidone is an atypical antipsychotic agent that is used for treatment of schizophrenia.
T4616 Metoclopramide Metoclopramide is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various cou...
TN1217 2'-O-Methylisoliquiritigenin 2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.
T2395L Vortioxetine hydrobromide Vortioxetine (Lu AA21004) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
T16399 Opiranserin Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is...
T8702 SKF-83566 SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
T0302 Triflupromazine hydrochloride Triflupromazine hydrochloride, an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.
T0137 Mirtazapine Mirtazapine is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevati...
T12899L SEP-363856 hydrochloride SEP-363856 hydrochloride is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-lik...
T0647 Tryptamine Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It ...
T6647 Rotigotine- Rotigotine is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal ...
T0482 Sertraline hydrochloride Sertraline hydrochloride is a selective serotonin uptake inhibitor that is used in the treatment of depression.
T0370 Pheniramine maleate Pheniramine Maleate, an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase ...
T2395 Vortioxetine Vortioxetine is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransfera...
T12207 NEO 376 NEO 376 is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.
T4369 SCH-23390 hydrochloride SCH 23390 hydrochloride is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).
T0351 Risperidone Risperidone is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
T0217 Levodropropizine Levodropropizine is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.
T4S1637 Gamma-Mangostin 1. Gamma-Mangostin as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic ...
T1445 Agomelatine Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) recep...
T0204 Protriptyline hydrochloride Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochlo...
T0039 Dapoxetine Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
T0074L Chlorprothixene hydrochloride Chlorprothixene brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene is a t...
T3275 Nefazodone hydrochloride Nefazodone is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.
T0236 Azatadine dimaleate Azatadine dimaleate is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).
T8946 Indophagolin Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and ...
TN1740 Homoeriodictyol Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
T0450 Fluoxetine Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
TQ0084 Lumateperone Tosylate Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist ...
T21629 Loxapine Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizo...
T6426 Buclizine dihydrochloride Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Bu...
T4494 CLOZAPINE N-OXIDE Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produ...
T4008 Metergoline Metergoline is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder ther...
T26543 AC-90179 HCl AC-90179 is a selective inverse agonist of 5-hydroxytryptamine2A receptor. It is an atypical antipsychotic pharmaceutical. It has been shown to alleviate halluci...
T0525 Flopropione Flopropione, a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
T0172 Maprotiline hydrochloride Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, in...
T15773 Lofepramine Lofepramine is an effective tricyclic antidepressant and is extensively metabolised to Desipramine. Lofepramine has significant anxiolytic efficacy in addition t...
T22904 L-745870 trihydrochloride highly potent and selective D4 dopamine receptor antagonist
pCPA methyl ester hydrochloride
T41143
Dopamine hydrochloride
T1644
Dopamine is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine b...
Procaine hydrochloride
T0802
Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds ...
Doxepin hydrochloride
T1540
Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mech...
Amitriptyline hydrochloride
T0678
Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
Fluvoxamine maleate
T1077
Fluvoxamine maleate is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
Chlorprothixene
T0074
Chlorprothixene is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.
WAY-100635 Maleate
T2631
WAY-100635 is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).
Metoclopramide hydrochloride hydrate
T8385
Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic
Azaphen
T7521
Azaphen is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
SCH-23390 maleate
T12865
SCH-23390 maleate is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, respectively).
5-Benzyloxygramine
T35841
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabili...
Iloperidone
T1539
Iloperidone is an atypical antipsychotic agent that is used for treatment of schizophrenia.
Metoclopramide
T4616
Metoclopramide is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various cou...
2'-O-Methylisoliquiritigenin
TN1217
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.
Vortioxetine hydrobromide
T2395L
Vortioxetine (Lu AA21004) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
Opiranserin
T16399
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is...
SKF-83566
T8702
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
Triflupromazine hydrochloride
T0302
Triflupromazine hydrochloride, an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.
Mirtazapine
T0137
Mirtazapine is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevati...
SEP-363856 hydrochloride
T12899L
SEP-363856 hydrochloride is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-lik...
Tryptamine
T0647
Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It ...
Rotigotine-
T6647
Rotigotine is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal ...
Sertraline hydrochloride
T0482
Sertraline hydrochloride is a selective serotonin uptake inhibitor that is used in the treatment of depression.
Pheniramine maleate
T0370
Pheniramine Maleate, an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase ...
Vortioxetine
T2395
Vortioxetine is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransfera...
NEO 376
T12207
NEO 376 is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.
SCH-23390 hydrochloride
T4369
SCH 23390 hydrochloride is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).
Risperidone
T0351
Risperidone is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
Levodropropizine
T0217
Levodropropizine is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.
gamma-Mangostin
T4S1637
1. Gamma-Mangostin as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic ...
Agomelatine
T1445
Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) recep...
Protriptyline hydrochloride
T0204
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochlo...
Dapoxetine
T0039
Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
Chlorprothixene hydrochloride
T0074L
Chlorprothixene brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene is a t...
Nefazodone hydrochloride
T3275
Nefazodone is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.
Azatadine dimaleate
T0236
Azatadine dimaleate is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).
Indophagolin
T8946
Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and ...
Homoeriodictyol
TN1740
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
Fluoxetine
T0450
Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
lumateperone Tosylate
TQ0084
Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist ...
Loxapine
T21629
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizo...
Buclizine dihydrochloride
T6426
Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Bu...
CLOZAPINE N-OXIDE
T4494
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produ...
Metergoline
T4008
Metergoline is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder ther...
AC-90179 HCl
T26543
AC-90179 is a selective inverse agonist of 5-hydroxytryptamine2A receptor. It is an atypical antipsychotic pharmaceutical. It has been shown to alleviate halluci...
Flopropione
T0525
Flopropione, a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
Maprotiline hydrochloride
T0172
Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, in...
Lofepramine
T15773
Lofepramine is an effective tricyclic antidepressant and is extensively metabolised to Desipramine. Lofepramine has significant anxiolytic efficacy in addition t...
L-745870 trihydrochloride
T22904
highly potent and selective D4 dopamine receptor antagonist
1 2 3 4 5 6 7 8 9