5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product name	CAS No.	Purity
TN4713	Onitisin	53823-03-3	98%
TN4713	Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
T0338	Minaprine	25905-77-5	98%
T0338	Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T13007	ST1936 oxalate	1782228-83-4	98%
T13007	ST1936 oxalate is a selective, nanomolar affinity agonist of 5-HT6 receptor(Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, re...
TQ0130	CP-809101	479683-64-2	98%
TQ0130	CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
T13021	Sulamserod	219757-90-1	98%
T13021	Sulamserod is an antagonist of 5-HT4 receptor, has antiarrhythmic activities.
T15414	GR 113808	144625-51-4	98%
T15414	GR 113808 displays 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. GR 113808 is a potent and highly selective antagonist of 5-HT4 r...
T12215	Nexopamil racemate	116759-35-4	98%
T12215	Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on platelet aggregation in vitro and on thrombus formation in vivo...
TN4092	Galanolactone	115753-79-2	98%
TN4092	Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
T2S0118	Daurinoline	2831-75-6	98%
T2S0118	Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a ...
T22340	Granisetron	109889-09-0	98%
T22340	Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
T4375	Methiothepin maleate	19728-88-2	98%
T4375	Methiothepin is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
T17275	YM348	372163-84-3	98%
T17275	YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).
T12859L	SB 243213 dihydrochloride	1780372-25-9	98%
T12859L	SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for h...
T6655	SB-269970 hydrochloride	261901-57-9	98%
T6655	SB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
T10989	Dehydroaripiprazole	129722-25-4	98%
T10989	Dehydroaripiprazole is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms d...
T16711	Flesinoxan	98206-10-1	98%
T16711	Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).
T15760	Lintopride	107429-63-0	98%
T15760	Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.
T13339	Wf-516	310392-94-0	98%
T13339	Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant activit...
T10075L2	2-Methyl-5-HT hydrochloride	845861-49-6	98%
T10075L2	2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
T10837L	Clocapramine	47739-98-0	98%
T10837L	Clocapramine is a D2 and 5-HT2A receptors antagonist.