TN4713 |
Onitisin
|
53823-03-3
|
98%
|
|
Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
|
T0338 |
Minaprine
|
25905-77-5
|
98%
|
|
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
|
T13007 |
ST1936 oxalate
|
1782228-83-4
|
98%
|
|
ST1936 oxalate is a selective, nanomolar affinity agonist of 5-HT6 receptor(Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, re...
|
TQ0130 |
CP-809101
|
479683-64-2
|
98%
|
|
CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
|
T13021 |
Sulamserod
|
219757-90-1
|
98%
|
|
Sulamserod is an antagonist of 5-HT4 receptor, has antiarrhythmic activities.
|
T15414 |
GR 113808
|
144625-51-4
|
98%
|
|
GR 113808 displays 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. GR 113808 is a potent and highly selective antagonist of 5-HT4 r...
|
T12215 |
Nexopamil racemate
|
116759-35-4
|
98%
|
|
Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on platelet aggregation in vitro and on thrombus formation in vivo...
|
TN4092 |
Galanolactone
|
115753-79-2
|
98%
|
|
Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
|
T2S0118 |
Daurinoline
|
2831-75-6
|
98%
|
|
Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a ...
|
T22340 |
Granisetron
|
109889-09-0
|
98%
|
|
Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
|
T4375 |
Methiothepin maleate
|
19728-88-2
|
98%
|
|
Methiothepin is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
|
T17275 |
YM348
|
372163-84-3
|
98%
|
|
YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).
|
T12859L |
SB 243213 dihydrochloride
|
1780372-25-9
|
98%
|
|
SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for h...
|
T6655 |
SB-269970 hydrochloride
|
261901-57-9
|
98%
|
|
SB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
|
T10989 |
Dehydroaripiprazole
|
129722-25-4
|
98%
|
|
Dehydroaripiprazole is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms d...
|
T16711 |
Flesinoxan
|
98206-10-1
|
98%
|
|
Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).
|
T15760 |
Lintopride
|
107429-63-0
|
98%
|
|
Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.
|
T13339 |
Wf-516
|
310392-94-0
|
98%
|
|
Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant activit...
|
T10075L2 |
2-Methyl-5-HT hydrochloride
|
845861-49-6
|
98%
|
|
2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
|
T10837L |
Clocapramine
|
47739-98-0
|
98%
|
|
Clocapramine is a D2 and 5-HT2A receptors antagonist.
|