9 (2,2 dicyanovinyl)julolidine

9-(2,2-Dicyanovinyl)julolidine (DCVJ) is a fluorogenic dye that is considered a fluorescent molecular rotor because its properties depend on the rotational relaxation of the molecule, which can be influenced by the viscosity of the solvent used. It has an excitation maximum at approximately 450 nm, and its emission is approximately 480 or 505 nm for low or high viscosity solvents, respectively. DCVJ has been used to study tubulin dynamics because its fluorescence increases when bound to tubulin sheets but is lower when bound to microtubules.

2-NBDG is a fluorescent indicator for direct glucose uptake measurement. It is an indicator of cell viability.

2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the degree of overall oxidative stress.

2-(4-Hydroxyphenylazo)benzoicacid is a spectrophotometric probe that shows changes in absorption spectra upon binding to proteins and binds to bovine serum proteins.

C.I. Vat Yellow 2 (Calcoloid Yellow GCD) is a yellow dye agent that can also be used to detect adsorption behavior on natural sediments.

6-Ethyl-7-hydroxy-4-methylchromen-2-one is a fluorescent dye.

Hoechst 34580 xHCl(23555-00-2(free base) is a cell-permeable fluorescent dye, is used for staining DNA and nuclei.

Rhod-2 AM is a fluorescent probe of the mitochondrion with λex of 552 nm and λem of 581 nm.

Hoechst 33258 analog 2 is part of a family of blue fluorescent dyes used to stain DNA.

2-Aminoacridone is a widely used fluorophore (λexc=428 nm, λem=525 nm).

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.

2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.

Mag-Fura-2 AM, a cell-permeable fluorescent compound, serves as a selective indicator for magnesium ions (Mg2+), demonstrating significant preference for Mg2+ over other bivalent ions including zinc (Zn2+), copper (Cu2+), and calcium (Ca2+). It notably exhibits over 13,000-fold greater selectivity for Mg2+ compared to Ca2+ (Mg2+Kd = 1.9 nM vs. Ca2+Kd = 25 μM). The excitation and emission peak wavelengths are 369 nm and 511 nm, respectively. Further, Mag-Fura-2 AM is utilized as an indirect measure of ATP consumption or production due to its magnesium ion sensitivity.

ING-2 AM is a membrane-permeable fluorescent indicator specifically designed for sodium ions (Na+), exhibiting a binding affinity with a dissociation constant (Kd) of 20 mM. With excitation and emission maxima (λ) at 525 nm and 545 nm respectively, this compound achieves a 20-fold selectivity over potassium ions (K+). It is utilized both in vitro and in situ to monitor real-time sodium influx.

Flutax-2 (5/6-mixture), an active fluorescent derivative of paclitaxel, binds to polymerized α,β tubulin dimers, with an excitation/emission wavelength of 496/524 nm. Derived from paclitaxel, a diterpenoid secondary metabolite from Taxus species utilized in various cancer research [1], it requires storage protection from light.

Sodium 4-(3-(4-hydroxy-5-isopropyl-2-methylphenyl)-1,1-dioxido-3H-benzo[c][1,2]oxathiol-3-yl)-2-isopropyl-5-methylphenolate is a useful organic compound for research related to life sciences. The catalog number is T66669 and the CAS number is 62625-21-2.

2-([1,1-Biphenyl]-4-yl)-5-phenyl-1,3,4-oxadiazole is a useful organic compound for research related to life sciences. The catalog number is T66233 and the CAS number is 852-38-0.

GNF-2-PEG-acid is usually used as a fluorescent probe.

CI Direct Brown 2 is a direct dye. It is soluble in water and ionizable to form colored anions. It also can directly dye cellulose fibers or protein fibers.

2-Aminobenzamide, a neutral and stable compound, is widely used as a fluorescent tag in glycan analysis and serves as the starting material for several important reactions.

C.I. Solvent Orange 2 is an agent of dye.

SBP-2, a sulfite bioluminescent probe (SBP), detects sulfite through a mechanism involving sulfite-mediated intramolecular cleavage [1].

2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate (ε-dATP), a fluorescent derivative of 2’-deoxyadenosine-5’-O-triphosphate (dATP), promotes sister chromatid exchange in stimulated primary mouse spleen T- and B lymphocytes with LPS or concanavalin A at concentrations of 50 to 150 µM. Utilized in ambiguous base pairing investigations within vinyl chloride-induced mutagenesis research, ε-dATP, along with its related compound ε-ATP—which exhibits an emission peak at 415 nm after being excited at 300 nm—contributes to understanding genetic alterations mechanisms.

7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b), a fluorescent hydroxylated derivative, serves as a probe for detecting hydroxyl radicals associated with DNA damage [1]. It should be protected from light for preservation.

Compound 1a, known as 1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea, serves as a fast-responsive fluorescent probe for detecting gold ions in water and synthetic products [1].

'2'-Fluo-AHC-c-di-GMP is a multifunctional dye used in biological experiments to observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology, and monitor microorganisms. Its applications range from basic scientific research to clinical diagnostics. Additionally, dyes are utilized in traditional fields such as textile dyeing and emerging fields like functional textile processing, food pigments, and dye-sensitized solar cells.

LipidGreen 2, a second-generation small molecule probe for lipid imaging, offers an enhanced fluorescence signal compared to the original LipidGreen. It selectively stains neutral lipids in cells and fat deposits in live zebrafish [1].

2-(Naphthalen-2-yl)-2-(pentyloxy)acetonitrile serves as a versatile dye employed in numerous applications. Dyes are crucial in biological experiments, aiding in the observation and analysis of cell structures, tracking of biomolecules, evaluation of cell functions, differentiation of cell types, detection of biomolecules, investigation of tissue pathology, and monitoring of microorganisms. Their utility extends beyond fundamental scientific research to encompass a broad spectrum of clinical diagnostics. Additionally, dyes find widespread use in traditional arenas like textile dyeing and in newer domains including functional textile processing, food coloring, and dye-sensitized solar cells.

BODIPY-cholesterol conjugate-2 (compound 6), a BODIPY-cholesterol conjugate, serves as an efficient probe for the simultaneous visualization of intracellular cholesterol pools and monitoring cholesterol efflux from cells to extracellular acceptors. (λex=589 nm, λem=638 nm) [1].

IPG-2 AM (APG-2 Acetoxymethyl ester) is a cell-permeable K+ fluorescent indicator.

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye that serves as an effective quencher for quantum dots (QDs) fluorescence, a capture probe for the virus antigen EV71, and a sensitive label for electrogenerated chemiluminescence (ECL) detection of matrix metalloproteinases (MMPs) [1] [2] [3].

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine, with a phosphatidylethanolamine head group, functions as a fluorescent probe to evaluate surface lipid oxidation in lipoproteins and plasma [1].

tert-Butyl 2-((diphenylmethylene)amino)acetate is a useful organic compound for research related to life sciences. The catalog number is T64928 and the CAS number is 81477-94-3.

Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells. It is a pentacarboxylate that displays excitation maxima of 340 and 380 nm at high and low calcium concentrations, respectively, when the emission is fixed at 510 nm, enabling determination of ratiometric measurements of calcium influx in live cells.

7-(Diethylamino)-4-methyl-2H-chromen-2-one is a useful organic compound for research related to life sciences. The catalog number is T66262 and the CAS number is 91-44-1.

Sodium 2,2',2'',2'''-((((1,1-dioxido-3H-benzo[c][1,2]oxathiole-3,3-diyl)bis(6-hydroxy-5-isopropyl-2-methyl-3,1-phenylene))bis(methylene))bis(azanetriyl))tetraacetate is a useful organic compound for research related to life sciences. The catalog number is T65315 and the CAS number is 1945-77-3.

AMCA-X, N-succinimidyl ester is an amine-reactive, UV-excitable, blue fluroscent dye.

8-(2-azidobenzylthio) NAD+ is a derivatized version of NAD+, a signaling molecule and enzyme cofactor, featuring an azido group (azidobenzylthio) that enables click chemistry applications.

Hoechst 33342 analog 2 is an analog of Hoechst 33342 which is a DNA minor groove binder.

SPiDER-βGal-2 is an effective probe for β-galactosidase activity, making it suitable for labeling live cells in culture [1].

Ru(bpy)2(phen-ITC)(PF6)2 is a versatile dye employed extensively across various domains, including biological experimentation and industrial applications. In biological settings, this dye enables scientists to observe and analyze cell structures, track biomolecules, evaluate cellular functions, differentiate between cell types, detect biomolecules, study tissue pathology, and monitor microorganisms. Its utility extends beyond scientific research, encompassing diagnostic uses in clinical settings. Additionally, Ru(bpy)2(phen-ITC)(PF6)2 finds application in traditional industries like textile dyeing and emerging sectors such as functional textile processing, food coloring, and dye-sensitized solar cells. This broad applicability underscores its significance in both scientific and industrial fields.

2-Aza-ε-adenosine (2-Aza-1,N6-ethenoadenosine) serves as a versatile dye with broad applications in various fields. As essential components in biological experimentation, dyes enable scientists to examine and track cell structures, monitor biomolecules, assess cellular functions, differentiate among cell types, explore tissue pathology, and scrutinize microorganisms. Their utility extends beyond biological research into clinical diagnostics, influencing a wide spectrum of industries including traditional textile dyeing, innovative textile processing, food coloring, and dye-sensitized solar cells.

Calcium Green BAPTA-2 AM serves as a fluorescent indicator for calcium ions.

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) serves as a fluorescent labeling reagent. It is utilized for labeling amines and has been successfully applied in the determination of activator amines using HPLC [1].

2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye featuring a nitrogen atom, potentially interacting with nitrogen introduced during the amination step [1].

N-(2-hydroxyethyl)-Naphthalimide is a fluorescent probe for nucleic acid detection whose fluorescence can be burst.

2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T65277 and the CAS number is 6950-82-9.

2-(7-Methoxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T64951 and the CAS number is 62935-72-2.