WST-8 is a water-soluble tetrazolium dye, the sensitivity of the WST-8(WST8)-based assay is higher than the conventional MTS-based assay.

Coumarin-PEG8-tetrazine is a derivative of the Coumarin dye featuring eight polyethylene glycol (PEG) units. This compound incorporates a tetrazine moiety that can participate in inverse electron-demand Diels-Alder (iEDDA) reactions with molecules containing a trans-cyclooctene (TCO) group.

8-Azido-cAMP, a fluorescent analog of cAMP, serves as a prototype for cAMP detection [1]. This click chemistry reagent features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. It is also competent for strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin serves as a pteridine-based fluorescent guanosine analogue and DNA uptake tracer utilized extensively for investigation into DNA binding and dynamics. It exhibits an absorbance peak at 350 nm and a corresponding emission peak at 430 nm [1].

6,7-Dimethyl-8-ribityllumazine is a biosynthetic precursor of Riboflavin (RBF). It serves as a noncovalently bound fluorophore of Lumazine protein (LumP), an accessory protein that exhibits fluorescence.

BODIPY-8-chloromethane, a fluorophore, serves as a fluorescent probe [1].

DG-8 serves as a potent inhibitor of STAT3-dependent transcription, exhibiting an IC50 of 0.98 μM, and also functions as a fluorescent probe endowed with a dansyl moiety [1].

8-Azidoadenosine-5'-O-diphosphate (8-azido-ADP), a clickable variant of the ATP precursor and purinergic receptor ligand ADP, serves as a photoaffinity label for proteins including glutamate dehydrogenase (GDH) isoproteins from bovine brains, as well as eukaryotic translation initiation factor 2 (eIF2) and guanine nucleotide exchange factor (GEF) from rabbit reticulocytes. Radiolabeled versions of this compound facilitate the identification of these protein interactions.

8-Phenyl-BODIPY 505/515, a phenyl-substituted derivative of BODIPY, serves as a fluorophore and is employed as a fluorescent probe [1] [2].

8-(4-Azidophenacylthio) NAD+ is a clickable variant of the essential signaling molecule and enzyme cofactor, NAD+.

8-(2-azidobenzylthio) NAD+ is a derivatized version of NAD+, a signaling molecule and enzyme cofactor, featuring an azido group (azidobenzylthio) that enables click chemistry applications.

8RK59 is a PARK7 inhibitor.

8-(4-iodophenyl)-1,3,5,7-tetramethyl BODIPY is a novel BODIPY fluorescent dye for the treatment of cytotoxicity.

Cyanine5 NHS ester bromide, a cyanine dye and active compound, is utilized for labeling amino groups in peptides, proteins, and oligonucleotides. It specifically labels fluorescence neurotensin (8-13) through arginine residues [1].

The cell-permeant pH indicator, carboxy SNARF-1, acetoxymethyl ester, acetate (CAS #126208-13-7) has a pKa of ~7.5 after de-esterification, thus is useful for measuring pH changes between pH 7 and pH 8. Carboxy-SNARF-1 exhibits a significant pH-dependent

Z-IETD-AFC is a fluorescent substrate for caspase-8 and granzyme B. It can be used to quantify cysteinyl aspartate-8 or granzyme B activity.

8-Aminopyrene-1,3,6-trisulfonic acid (APTS) is an anionic fluorescent dye with excitation/emission spectra of 425/503 nm, respectively. It forms a ground state complex with viologen-type quenchers, inducing a red-shift in the absorbance spectrum from 425 to 464 nm. APTS is pH insensitive, with the emission maximum remaining constant over the pH range of 4-10. It can be used in solution or immobilized through attachment of an aldehyde functionalized monomer by reductive amination without significantly changing fluorescence intensity. APTS has been used as a reporter for glucose sensing and for the detection of other saccharides.

D&C Red No. 8 is a dye.

Ac-IETD-AMC, a fluorogenic substrate specific for caspase-8 and granzyme B with an acetyl (Ac) moiety, is commonly utilized to quantify caspase-8 activity [1].

Derivative of N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. Incorporated into bacterial peptidoglycans during biosynthesis. Suitable for fluorescent labeling of peptidoglycans when 'click'-conjugated to a fluorescent dye. Liang et al (2017) Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications. Nat.Commun. 8 15015 PMID:28425464 |DeMeester et al (2018) Synthesis of functionalized N-Acetyl muramic acids to probe bacterial cell wall recycling and biosynthesis. J.Am.Chem.Soc 140 9458 PMID:29986130

Tris-acetate is a useful organic compound for research related to life sciences. The catalog number is T65448 and the CAS number is 6850-28-8.

Di-8-ANEPPS, a voltage-sensitive dye, demonstrates shifts in both its fluorescence excitation and emission spectra in response to changes in membrane potential (Vm).

Ac-LETD-AFC is a fluorescent substrate specifically cleaved by caspase-8 and can be used to quantify caspase activity by fluorescence detection of free AFC.Ac-LETD-AFC has an excitation wavelength of 400 nm and an emission wavelength of 505 nm.

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1), it demonstrates increased specificity against collagenases (MMP-1, MMP-8, MMP-13) and MT1-MMP, evidenced by higher specificity constants (Ex/Em=325 nm/400 nm). [1]