a-8

Acetylcytisine (11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene) is a natural product of The herbs of Genista tinctoria L.

7(8)-Dehydroschisandrol A (Compound 4a), a lignan extracted from Schizandra chinensis Baill, exhibits a mild inhibitory activity against stress-induced gastric ulcers [1].

An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine and bisdeoxynarciclasine is provided, this antitumor agent has an advantage of having an excellent therapeutic effect of tumor and less side effects.

Junipediol A 8-glucoside is a useful organic compound for research related to life sciences. The catalog number is T125496 and the CAS number is 188894-18-0.

1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive deficits and oxidative stress in AD mice; can exert antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity.

Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.

8-Amino-1-Naphthalenesulfonic Acid is a naphthalene derivative used as a fluorescent dye and as a reagent in organic synthesis. It is a highly fluorescent compound with a high Stokes shift, making it an ideal fluorescent marker for a wide range of biological systems.

Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhibitor of human cathepsin B. It has antimalarial activity in trials significant affinities towards the Delta-1, kappa opioid receptors (as an antagonist) and binds to benzodiazepine receptors. Amentoflavone may be a potential lead for a new type of anti-inflammatory agents having the dual inhibitory activity of group II phospholipase A2 and cyclooxygenase. Amentoflavone and quercetin differentially exerted suppression of PGE2 biosynthesis via downregulation of COX-2/iNOS expression.

(S)-(+)-ochracin (8-hydroxy-3-methyl-3,4-dihydroisochromen-1-one) is a marine derived natural products found in Helicascus kanaloanus.

γ-Glu-Phe TFA(7432-24-8 free base) is a dipeptide composed of gamma-glutamate and phenylalanine and is a proteolytic breakdown product of larger proteins. It is probably formed by transpeptidation between glutathione and the corresponding amino acid, catalyzed by gamma-glutamyl transpeptidase.

Ergostenol (Ergost-8(14)-en-3beta-ol) is a biological precursor and a provitamin of vitamin D2.

8-Acetyl-7-Hydroxycoumarin is a natural compound,with Antifungal and antibacterial activities

5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity.

ALPHA-PINENE ((-)-Alpha-Pinene) is a bicyclic monoterpene found in pine trees and other plants, including Cannabis with diverse biological activities [1]. It reduces the growth of a panel of seven Gram-positive bacteria, seven Gram-negative bacteria, and eight yeast strains with MIC values of 0.75-1.29, 1.05-1.59, and 0.7-1.17%, respectively [2]. It has insecticidal activity against C. molestus larvae with LC50 values ranging from 47 to 49 mg/L.3 ALPHA-PINENE (100 μg/ml) induces apoptosis, increases anion superoxide production and DNA fragmentation, and activates caspase-3 in B16/F10 melanoma cells [4]. In a B16/F10 mouse xenograft model, ALPHA-PINENE(100 ml of a 10 mg/ml solution) reduces the number of metastatic lung nodules by approximately 7-fold. ALPHA-PINENE(8.6 mg/L, aerosol) also increases the time spent in the open arms of the elevated plus maze by approximately 2-fold in mice, indicating anxiolytic-like activity [5].

α-Hydroxyglutaric Acid is a natural product for research related to life sciences. The catalog number is T36624 and the CAS number is 2889-31-8.This compound is unstable in powder form and other related salt forms are recommended.

Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).

Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.

Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.

Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregulating HIF-1αand VEGF.

Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) is a Standardized Chemical Allergen. The physiologic effect of chlorquinaldol is by means of Increased Histamine Release, and Cell-mediated Immunity.

Delta-Nonalactone is a natural product for research related to life sciences. The catalog number is TN6697 and the CAS number is 3301-94-8.

(8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside (MDG) is a natural compound extracted from Trachelospermum asiaticum [1].

8-Hydroxy-3,5,7,3',4',5'-hexamethoxyflavone is a natural product for research related to life sciences. The catalog number is TN3279 and the CAS number is 202846-95-5.

Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-xylopyranoside is a natural product from Viola yedoensis.

8-Debenzoylpaeoniflorin is a natural product from plants

Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside, also known as compound 8, is a flavonoid glycoside isolated from the leaf extract of the black locust (Leguminosae)[1].

Blepharotriol, a phenolic triterpene isolated from Maytenus blepharodes, exhibits antimicrobial activity, with a minimum inhibitory concentration (MIC) of 8-4 µg/ml against Bacillus subtilis. It also demonstrates cytotoxic activity, with half-maximal inhibitory concentrations (IC50s) of 12.2 µM for HeLa cells, and greater than 20 µM for both Hep-2 and Vero cells [1].

8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin compound present in Heracleum pyrenaicum Lam.

25-O-Methylkaravilagenin D is a natural product for research related to life sciences. The catalog number is TN6315 and the CAS number is 1363422-85-8.

1-(3,4,5-Trihydroxypentanoyl)-β-carboline is a natural product for research related to life sciences. The catalog number is TN6093 and the CAS number is 180995-40-8.

19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.1,2It inhibits actin polymerization in a cell-free assay when used at a concentration of 2 μM.219-O-Acetylchaetoglobosin A (3.2, 10, and 32 μg/ml) is cytotoxic to HeLa cervical cancer cells.1 1.Umeda, M., Ohtsubo, K., Saito, M., et al.Cytotoxicity of new cytochalasans from Chaetomium globosumExperientia31(4)435-438(1975) 2.Sekita, S., Yoshihira, K., Natori, S., et al.Structure-activity relationship of thirty-nine cytochalasans observed in the effects on cellular structures and cellular events and on actin polymerization in vitroJ. Pharmacobiodyn.8(11)906-916(1985)

2',4'-Dihydroxy-3,7':4,8'-diepoxylign-7-ene is a natural product for research related to life sciences. The catalog number is TN2716 and the CAS number is 666250-52-8.

6-O-(p-Hydroxybenzoyl)glucose is a natural product for research related to life sciences. The catalog number is TN5833 and the CAS number is 202337-44-8.

8-Isoprostaglandin F2α is a natural product for research related to life sciences. The catalog number is T37164 and the CAS number is 27415-26-5.

Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy-5, 8, 10, 14-eicosatetraenoic acid (12-HETE).

Fengycin, a cyclic lipopeptide, functions as an agricultural fungicide by exhibiting an anti-fungal infection effect through damaging the target's cell membrane[1].

1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin and swertiamarin show significant hepatoprotective effect in the liver damage model induced by alpha-naphthylisot hiocyanate. 3. Swertianolin shows anti-acetylcholinesterase activity effects. 4. Swertianolin shows that it can scavenge superoxide and hydroxyl radicals with the studying method of the autoxidation of Pyrogallol and afenton.

Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product for research related to life sciences. The catalog number is TN6287 and the CAS number is 1448779-19-8.

3,5,7-Trihydroxy-3',4',5'-trimethoxyflavone is a natural product for research related to life sciences. The catalog number is TN2891 and the CAS number is 146132-95-8.

[6]-Gingerdiol is a natural product for research related to life sciences. The catalog number is TN5765 and the CAS number is 154905-69-8.

8-Hydroxypinoresinol has antioxidant activity,it and phillygenin significantly reduce the cell injury by 3-morpholinosydnonimine (SIN-1), a ONOO- generator, may be useful for the therapeutic or preventive applications in treating ONOO--related diseases.

trans-Methylkhellactone is a natural product for research related to life sciences. The catalog number is TN5167 and the CAS number is 23733-92-8.

Vanicoside B is a natural product for research related to life sciences. The catalog number is TN6220 and the CAS number is 155179-21-8.

Physcion 8-O-rutinoside is a natural product from Rhamnus libanoticus.

Tamarixin is a natural product for research related to life sciences. The catalog number is TN5514 and the CAS number is 27542-39-8.

Jacareubin is a natural product for research related to life sciences. The catalog number is TN6127 and the CAS number is 3811-29-8.

Platycoside M1 is a natural product for research related to life sciences. The catalog number is TN4806 and the CAS number is 917482-67-8.

Phochinenin G is a natural product for research related to life sciences. The catalog number is TN5737 and the CAS number is 1070883-75-8.

Kayaflavone is a natural product for research related to life sciences. The catalog number is TN5511 and the CAS number is 481-45-8.

Paeoniflorgenin is a deglucosylated metabolite of Paeoniflorin[1]. [1]. Hsiu SL, et, al. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. Planta Med. 2003 Dec; 69(12): 1113-8.