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  • Inhibitors & Agonists
    1039
    TargetMol | Activity
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    5
    TargetMol | inventory
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    73
    TargetMol | natural
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    2
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    155
    TargetMol | natural
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    1049
    TargetMol | composition
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    23
    TargetMol | Activity
Ethyl Vanillate
T2929617-05-0
Ethyl Vanillate (Bourbonal) , a vanillin analog, is a flavoring agent that exhibits strong antioxidant activity.
  • $41
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BISMUTH SUBGALLATE
T450299-26-3
Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.
  • $30
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Doxazosin mesylate
T010177883-43-3
Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.
  • $38
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Methyl Vanillate
T28183943-74-6
Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. Methyl vanillate is considered to be a slightly soluble (in water) acidic compound. Methyl vanillate can be synthesized from vanillic acid. Methyl vanillate has been identified in foods such as cow's milk and beer.
  • $42
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Atracurium besylate
T639764228-81-5
Atracurium besylate (51W89) is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.
  • $30
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Sodium taurocholate
TWA2417145-42-6
Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid.[3] These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.
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Imatinib Mesylate
T1621220127-57-1
Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR, respectively).
  • $54
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Osimertinib mesylate
T36341421373-66-1
Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib mesylate has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.
  • $45
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S-Adenosyl-L-methionine disulfate tosylate
T675297540-22-2
S-Adenosyl-L-methionine disulfate tosylate (Ademetionine disulfate tosylate) is the disulfate-tosylate mixed salt comprising diastereoisomers of ademetionine ions. Ademetionine exhibits anti-inflammatory properties and has been utilized in the treatment of chronic liver disease.
  • $32
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Sunitinib Malate
T0374341031-54-7
Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit.
  • $37
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Sodium salicylate
T033554-21-7
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
  • $45
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Methyl acetylsalicylate
TN6710580-02-9
Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) is a natural product isolated from Pisum sativum. Inhibition of collagen-induced human platelet rich plasma aggregation
  • $50
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Dabigatran Etexilate Mesylate
T5133872728-81-9
Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).
  • $35
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Ethamsylate
T00022624-44-4
Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis and action of prostaglandins.
  • $32
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Ethyl gallate
T3729831-61-8
Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhibit the abilities of invasion of breast cancer in vitro by inhibiting the mRNA levels of MMP-9/MMP-2, phosphorylation of Akt and protein expression of NF-κB and inhibits hydrogen peroxide signaling, may represent an alternative class of vasopressors for use in septic shock. Also, Ethyl gallate suppresses proliferation and invasion in human breast cancer cells by modulating the PI3K/Akt pathway, which may contribute to inhibiting their downstream targets such as NF-κB p-65, Bcl-2/Bax, and mRNA levels of MMP-2 and MMP-9 in breast cancer cells, could be used as potential antioxidants with safe therapeutic application in cancer chemotherapy.
  • $42
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Tauroursodeoxycholate sodium
T699335807-85-3
Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
  • $30
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Sorafenib tosylate
T0093475207-59-1
Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
  • $37
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Ibutamoren Mesylate
T7112159752-10-0
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.
  • $57
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Propyl gallate
T3S1866121-79-9
Propyl gallate (Gallic acid propyl esterZ) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.
  • $48
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Methyl indole-3-carboxylate
T5868942-24-5
Methyl indole-3-carboxylate (Methyl 3-indolecarboxylate) is a natural product isolated from Heracleum candicans.
  • $42
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Dicyclo hexyl Phthalate
T511984-61-7
Dicyclohexyl Phthalate is a solid plasticizer.
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4-Nonylphenol polyethoxylate
T082426027-38-3
4-Nonylphenol polyethoxylate (Nonoxinol-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. 4-Nonylphenol polyethoxylate has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.
  • $41
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Methyl salicylate
T0399119-36-8
Methyl salicylate (Gaultheria oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments.
  • $33
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Benorilate
T32765003-48-5
Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
  • $39
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Monoethyl pimelate
T1836333018-91-6
Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1].
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Methyl 4-bromopyrrole-2-carboxylate
TN7163934-05-4
Methyl 4-bromopyrrole-2-carboxylate (4-Bromo-2-(methoxycarbonyl)-1H-pyrrole) is a marine derived natural products found in Lissodendoryx sp.
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Eprosartan Mesylate
T2531144143-96-4
Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.
  • $40
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Naftidrofuryl oxalate
T10813200-06-4
Naftidrofuryl oxalate (Nafronyl oxalate) is a drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. It may also be an antagonist at 5HT-2 serotonin receptors.
  • $33
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Bepotastine Besilate
T6405190786-44-8
Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).
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Rasagiline Mesylate
T6962161735-79-1
Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
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Camostat mesylate
T239159721-29-8
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
  • $43
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Safinamide mesylate
T6651202825-46-5
Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
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Dabrafenib Mesylate
T84741195768-06-9
Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).
  • $40
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tert-Butyl5-bromo-1H-indole-1-carboxylate
T77351182344-70-3
Tert-Butyl5-bromo-1H-indole-1-carboxylate (N-Boc-5-bromoindole) is an indole derivative with therapeutic potential for pain, inflammation, and other conditions.
  • $29
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Pefloxacin Mesylate Dihydrate
T0425L149676-40-4
Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting DNA gyrase (topoisomerase).
  • $38
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Lapatinib Ditosylate
T6235388082-77-7
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
  • $39
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Butylated hydroxytoluene
T0935128-37-0
Butylated hydroxytoluene (BHT FCC/NF) is an antioxidant widely used in food, cosmetics and industrial liquids. It is a ferroptosis inhibitor.
  • $33
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Methyl Cholate
T27441448-36-8
Methyl Cholate is the methyl ester form of cholic acid. Methyl Cholate is the methyl ester form of bile acid, which is a major bile acid produced by the liver and synthesized from cholesterol.Methyl Cholate has anti-inflammatory and anti-tumor activity.
  • $42
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Carbasalate calcium
T36085749-67-7
Carbasalate calcium (Rheomin) is an analgesic, antipyretic, and anti-inflammatory drug, as well as a platelet aggregation inhibitor.
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Mesoxalate sodium (monohydrate)
T491431635-99-1
Mesoxalate sodium (monohydrate) is primarily located in the cytoplasm within the cell. Mesoxalic acid can be biosynthesized from malonic acid. Outside of the human body, mesoxalic acid can be found in cereals and cereal products, common pea, and herbs and spices.
  • $41
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Ethyl indole-2-carboxylate
T643853770-50-1
Ethyl indole-2-carboxylate is a indole derivative. Ethyl indole-2-carboxylate inhibits bezodiazepine receptor with IC50 of 2.2mM.
  • $29
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Mebhydrolin napadisylate
T01136153-33-9
Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
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Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate
T777052436-79-5
Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate is a biochemical reagent that can be used in biochemical reactions.
  • $30
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Kukoamine B mesylate
T7026L1375179-86-4In house
Kukoamine B mesylate is a novel cationic alkaloid derived from dermatophytes with antioxidant activity, inhibits LPS internalization in Kupffer and RAW 264.7 cells, and can be used to study acute inflammation and diabetes.
  • $195
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Memantine Related Compound B
T0535707-37-9
Memantine Related Compound B (3,5-Dimethyl-1-adamantanol) is an impurity of Memantine.
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Ethyl salicylate
TN1625118-61-6
Ethyl salicylate is a natural product
  • $50
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Pefloxacin Mesylate
T042570458-95-6
Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
  • $33
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Dehydrocholate sodium
T0516145-41-5
Dehydrocholate sodium, a hydrocholeretic, can increase bile output to clear increased bile acid load.
  • $42
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Doxycycline (hyclate)
T1687L24390-14-5
Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor activity.
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