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Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Cat No. product name
T9857L Vasopressin acetate Vasopressin acetate 是一种环状九肽,在下丘脑中枢合成。 Vasopressin acetate 作为一种神经递质,通过与特定的 G 蛋白偶联受体结合发挥其作用。
T22300 Creatine monohydrate Creatine monohydrate 是磷酸原能量系统的关键参与者,尤其是在肌肉和大脑中。 Creatine monohydrate 是高强度、短期活动中 ATP 的主要来源。
TN6833 Octanal octanal 是一种具有抗氧化和抗菌活性的天然产物。
TN3748 D-Asparagine D-Asparagine 是酵母菌株的氮源。 D-Asparagine 是 L-Asparagine 水解的竞争性抑制剂 (Ki = 0.24 mM)。
T40729 D-Threonine D-Threonine 是酿酒酵母 Saccharomyces cerevisiae 的代谢产物之一。
T16527 Phytic acid dodecasodium salt hydrate Phytic acid dodecasodium salt hydrate 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化酶,IC50 为 6 mM,并具有抗氧化、神经保护和抗炎作用。
T41286 N6-Isopentenyladenosine N6-Isopentenyladenosine 是甲羟戊酸途径的终产物,是一种具有抗黑色素瘤活性的自噬抑制剂。 N6-Isopentenyladenosine 是一种在细胞分裂素中发现的 RNA 修饰,可调节植物生长/分化,提高翻译的效率和准确性。
T5565 Undecanedioic acid Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specific...
TMS2181 Trans-Zeatin Trans-Zeatina is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
T5086 Pharmatose DCL 14 Lactose is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Lactose is also an important osm...
T2857 2,5-Dihydroxybenzoic acid Gentisic acid is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and an...
T5878 β-Glycerophosphate disodium salt pentahydrate β-Glycerol phosphate disodium salt pentahydrate is a protein phosphatase inhibitor.
T1644 Dopamine hydrochloride Dopamine is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine b...
T4829 3-Hydroxyphenylacetic acid 3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxypheny...
T4920 2-Ketoglutaric acid Sodium alpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase a...
T0877 Gallic acid Gallic acid is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
T4743 Uridine 5′-diphosphoglucose disodium salt UDP-Glucose sodium salt is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 =...
TQ0273 Neopterin D-(+)-Neopterin, a catabolic product of guanosine triphosphate. In humans, neopterin is involved in purine biosynthesis.
T6820 D-α-Hydroxyglutaric acid disodium Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
T5081 Adenine monohydrochloride hemihydrate Adenine is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfecte...
Fr13756 Isonicotinic acid Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinoly...
T14002 12-Ketodeoxycholic acid 12-Ketodeoxycholic acid is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury[1]
T4760 KSD 2405 3-Hydroxybenzyl alcohol (CAS Number 620-24-6) is a hydroxybenzyl alcohol that is phenol substituted at position C-3 by a hydroxymethyl group. It is a pink or bei...
T7068 Eicosapentaenoic acid ethyl ester Eicosapentaenoic acid ethyl ester is an omega-3 fatty acid agent.
T2321 Protodioscin Protodioscin is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
T4819 Pipecolic acid Pipecolic acid, a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and hum...
T1658 Selenomethionine DL-Selenomethionine is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorpora...
T0709 Natamycin Natamycin is a Polyene Antimicrobial.
T0581 Isomaltose Isomaltose is a reducing disaccharide, similar to maltose, but with an α-(1-6)-linkage instead of the α-(1-4)-linkage.
T5224 2-Hydroxyhexanoic acid 2-Hydroxycaproic acid is a branched-chain alpha-keto acid that has been reported in normal human blood and in normal amniotic fluid. It has been found that 2-Hyd...
T5083 L-Cysteic acid monohydrate L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
T0437 Inosine Inosine is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesi...
T2748 Cortodoxone Cortodoxone is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
T3093 Spermine tetrahydrochloride Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA fro...
T5277 3-Furanoic acid 3-Furoic acid is an organic acid regularly occurring in the urine of healthy individuals. 3-Furoic acid is also a compound found in honey and honeydew samples.
T2910 Flavonol 3-hydroxyflavone is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate...
T4842 1H-pyrazole 1H-Pyrazole, is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic,...
T4843 2,2-Dihydroxyacetic acid Glyoxylic acid or oxoacetic acid is an organic compound that is both an aldehyde and a carboxylic acid.It is an intermediate of the glyoxylate cycle, which enabl...
T0414 D-Mannitol Mannitol is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any ...
T0848 L-DOPA Levodopa is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and c...
T5226 2-(2-Methylbenzamido)acetic acid Methylhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in bo...
T5290 (S)-2-Hydroxy-3-phenylpropanoic acid L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of la...
T3919 Ginsenoside Rb2 Ginsenoside Rb2 found in species of Panax, upregulating GPR120 gene expression.
T3950 Tridecanoic acid Tridecanoic acid is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been ident...
T0671 2-Naphthol 2-Naphthol is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring.
T5693 Pyrroloquinoline quinone disodium salt Methoxatin disodium salt, an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a...
T0689 D-Phenylalanine D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).
T5253 3-Methyladipic acid 3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-o...
T4707 3-Hydroxyanthranilic acid 3-Hydroxyanthranilic acid, also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives...
T7711 Uridine triphosphate Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
Vasopressin acetate
T9857L
Vasopressin acetate 是一种环状九肽,在下丘脑中枢合成。 Vasopressin acetate 作为一种神经递质,通过与特定的 G 蛋白偶联受体结...
Creatine monohydrate
T22300
octanal
TN6833
octanal 是一种具有抗氧化和抗菌活性的天然产物。
D-Asparagine
TN3748
D-Asparagine 是酵母菌株的氮源。 D-Asparagine 是 L-Asparagine 水解的竞争性抑制剂 (Ki = 0.24 mM)。
D-Threonine
T40729
D-Threonine 是酿酒酵母 Saccharomyces cerevisiae 的代谢产物之一。
Phytic acid dodecasodium salt hydrate
T16527
Phytic acid dodecasodium salt hydrate 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化...
N6-Isopentenyladenosine
T41286
Undecanedioic acid
T5565
Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specific...
trans-Zeatin
TMS2181
Trans-Zeatina is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
Pharmatose DCL 14
T5086
Lactose is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Lactose is also an important osm...
2,5-Dihydroxybenzoic acid
T2857
Gentisic acid is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and an...
β-Glycerophosphate disodium salt pentahydrate
T5878
β-Glycerol phosphate disodium salt pentahydrate is a protein phosphatase inhibitor.
Dopamine hydrochloride
T1644
Dopamine is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine b...
3-Hydroxyphenylacetic acid
T4829
3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxypheny...
2-Ketoglutaric acid Sodium
T4920
alpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase a...
Gallic acid
T0877
Gallic acid is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
Uridine 5′-diphosphoglucose disodium salt
T4743
UDP-Glucose sodium salt is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 =...
Neopterin
TQ0273
D-(+)-Neopterin, a catabolic product of guanosine triphosphate. In humans, neopterin is involved in purine biosynthesis.
D-α-Hydroxyglutaric acid disodium
T6820
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
Adenine monohydrochloride hemihydrate
T5081
Adenine is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfecte...
Isonicotinic acid
Fr13756
Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinoly...
12-Ketodeoxycholic acid
T14002
12-Ketodeoxycholic acid is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury[1]
KSD 2405
T4760
3-Hydroxybenzyl alcohol (CAS Number 620-24-6) is a hydroxybenzyl alcohol that is phenol substituted at position C-3 by a hydroxymethyl group. It is a pink or bei...
Eicosapentaenoic acid ethyl ester
T7068
Eicosapentaenoic acid ethyl ester is an omega-3 fatty acid agent.
Protodioscin
T2321
Protodioscin is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
Pipecolic acid
T4819
Pipecolic acid, a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and hum...
Selenomethionine
T1658
DL-Selenomethionine is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorpora...
Natamycin
T0709
Natamycin is a Polyene Antimicrobial.
Isomaltose
T0581
Isomaltose is a reducing disaccharide, similar to maltose, but with an α-(1-6)-linkage instead of the α-(1-4)-linkage.
2-Hydroxyhexanoic acid
T5224
2-Hydroxycaproic acid is a branched-chain alpha-keto acid that has been reported in normal human blood and in normal amniotic fluid. It has been found that 2-Hyd...
L-Cysteic acid monohydrate
T5083
L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
Inosine
T0437
Inosine is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesi...
Cortodoxone
T2748
Cortodoxone is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
Spermine tetrahydrochloride
T3093
Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA fro...
3-Furanoic acid
T5277
3-Furoic acid is an organic acid regularly occurring in the urine of healthy individuals. 3-Furoic acid is also a compound found in honey and honeydew samples.
Flavonol
T2910
3-hydroxyflavone is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate...
1H-pyrazole
T4842
1H-Pyrazole, is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic,...
2,2-Dihydroxyacetic acid
T4843
Glyoxylic acid or oxoacetic acid is an organic compound that is both an aldehyde and a carboxylic acid.It is an intermediate of the glyoxylate cycle, which enabl...
D-Mannitol
T0414
Mannitol is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any ...
L-DOPA
T0848
Levodopa is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and c...
2-(2-Methylbenzamido)acetic acid
T5226
Methylhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in bo...
(S)-2-Hydroxy-3-phenylpropanoic acid
T5290
L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of la...
Ginsenoside Rb2
T3919
Ginsenoside Rb2 found in species of Panax, upregulating GPR120 gene expression.
Tridecanoic acid
T3950
Tridecanoic acid is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been ident...
2-Naphthol
T0671
2-Naphthol is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring.
Pyrroloquinoline quinone disodium salt
T5693
Methoxatin disodium salt, an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a...
D-Phenylalanine
T0689
D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).
3-Methyladipic acid
T5253
3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-o...
3-Hydroxyanthranilic acid
T4707
3-Hydroxyanthranilic acid, also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives...
Uridine triphosphate
T7711
Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
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