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Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Cat. No. Product name CAS No. Purity Chemical Structure
TQ0285L Spaglumic acid acetate 99.49%
Spaglumic acid acetate is a neuropeptide found in millimolar concentrations in brain.
T7711 Uridine triphosphate 63-39-8 98%
Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
TN3910 Ecdysone 3604-87-3 100%
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
T14063 7α,25-Dihydroxycholesterol 64907-22-8
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholes...
T29011 Triiodothyronine Sulfate 31135-55-4
Triiodothyronine Sulfate is a prodrug to the Conventional Hormone Therapy of Hypothyroidism. Triiodothyronine sulfate is the main metabolite of thyroid hormone t...
T7475 S-Adenosyl-L-methionine 29908-03-0 98%
S-Adenosyl-L-methionine is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
T37961 P-Tolualdehyde 104-87-0 98%
p-Tolualdehyde is a RIFM flavor that shows inhibition of mushroom tyrosinase.
T14545 Berberine chloride hydrate 68030-18-2 98%
Berberine chloride hydrate is an alkaloid commonly used as an antibiotic.Berberine chloride hydrate has antitumor activity, induces the generation of reactive ox...
T8110 (+)-Longifolene 475-20-7 98%
(+)-Longifolene is a naturally occurring.
T9455 4-hydroxyestrone-4-methyl ether 58562-33-7 98%
4-hydroxyestrone-4-methyl ether is the methylation of 4-OHE1, which is catalyzed by COMT.
T10029 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine 35418-59-8 98%
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that has been found in the aging mouse brain.
T10185 6-Phosphogluconic acid 921-62-0 98%
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor (Kis: 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphat...
T19443L N-Acetylhistamine acetate 98%
N-Acetylhistamine acetate is a histamine metabolite. It can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
T37991 15-keto Prostaglandin F2α 35850-13-6 98%
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
T10020 1-Methyluric acid 708-79-2 98%
1-Methyluric acid acts on the bladder mucosa and increases the levels of insulin, triglycerides, cholesterol, and blood glucose.
T40887 N1,N12-Diacetylspermine dihydrochloride 77928-71-3 98%
N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. The occurrence of cancer is associated with the up-regulation of N1,N12-Diacety...
T8282 (S)-(−)-Perillyl alcohol 18457-55-1 98%
(S)-( )-Perillyl alcohol, a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis....
T19346 5'-Guanylic acid 85-32-5 98%
5'-Guanylic acid is involved in several metabolic disorders, including AICA-ribosiduria pathway, adenosine deaminase deficiency,adenine phosphoribosyltransferas...
T36667 2'-Deoxyadenosine-5'-triphosphate 1927-31-7 98%
2'-Deoxyadenosine-5'-triphosphate (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-...
T5614 3-Oxopentanedioic acid 542-05-2 98%
3-oxoglutaric acid or acetonedicarboxylic acid is a simple carboxylic acid, which may be used as a building block in organic chemistry. It has been found to be a...
Spaglumic acid acetate
TQ0285L
Spaglumic acid acetate is a neuropeptide found in millimolar concentrations in brain.
Uridine triphosphate
T7711
Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
Ecdysone
TN3910
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
7α,25-Dihydroxycholesterol
T14063
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholes...
Triiodothyronine Sulfate
T29011
Triiodothyronine Sulfate is a prodrug to the Conventional Hormone Therapy of Hypothyroidism. Triiodothyronine sulfate is the main metabolite of thyroid hormone t...
S-Adenosyl-L-methionine
T7475
S-Adenosyl-L-methionine is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
P-Tolualdehyde
T37961
p-Tolualdehyde is a RIFM flavor that shows inhibition of mushroom tyrosinase.
Berberine chloride hydrate
T14545
Berberine chloride hydrate is an alkaloid commonly used as an antibiotic.Berberine chloride hydrate has antitumor activity, induces the generation of reactive ox...
(+)-Longifolene
T8110
(+)-Longifolene is a naturally occurring.
4-hydroxyestrone-4-methyl ether
T9455
4-hydroxyestrone-4-methyl ether is the methylation of 4-OHE1, which is catalyzed by COMT.
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
T10029
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that has been found in the aging mouse brain.
6-Phosphogluconic acid
T10185
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor (Kis: 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphat...
N-Acetylhistamine acetate
T19443L
N-Acetylhistamine acetate is a histamine metabolite. It can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
15-keto Prostaglandin F2α
T37991
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
1-Methyluric acid
T10020
1-Methyluric acid acts on the bladder mucosa and increases the levels of insulin, triglycerides, cholesterol, and blood glucose.
N1,N12-Diacetylspermine dihydrochloride
T40887
N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. The occurrence of cancer is associated with the up-regulation of N1,N12-Diacety...
(S)-(−)-Perillyl alcohol
T8282
(S)-( )-Perillyl alcohol, a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis....
5'-Guanylic acid
T19346
5'-Guanylic acid is involved in several metabolic disorders, including AICA-ribosiduria pathway, adenosine deaminase deficiency,adenine phosphoribosyltransferas...
2'-Deoxyadenosine-5'-triphosphate
T36667
2'-Deoxyadenosine-5'-triphosphate (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-...
3-Oxopentanedioic acid
T5614
3-oxoglutaric acid or acetonedicarboxylic acid is a simple carboxylic acid, which may be used as a building block in organic chemistry. It has been found to be a...
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