Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No.	Product name	CAS No.	Purity
T4922	Uridine 5′-triphosphate tris salt	T4922	99.94%
T4922	Uridine 5′-triphosphate tris salt (Uridine 5'-triphosphoric acid) is an agonist to the P2Y receptor and has been used to study concentrations of intracellular Ca...
TQ0285L	Spaglumic acid acetate		99.49%
TQ0285L	Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.
T14545	Berberine chloride hydrate	68030-18-2	98.94%
T14545	Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid commonly used as an antibiotic.Berberine chloride hydrate has antitumor activity, ...
T7711	Uridine triphosphate	63-39-8	98%
T7711	Uridine triphosphate (Uridine 5'-triphosphate) increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
T13870	Riboflavine phosphate	146-17-8	97.93%
T13870	Riboflavine phosphate (Flavin mononucleotide) is a derivative of Riboflavin. Riboflavin phosphate can be used to study keratoconus, corneal dilatation, and irreg...
T19461	N1,N8-Diacetylspermidine	82414-35-5	100%
T19461	N1,N8-Diacetylspermidine is a polyamine found in human urine.N1,N8-Diacetylspermidine can be used as a marker for cancer and malignancy.
TN3910	Ecdysone	3604-87-3	100%
TN3910	Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
T19346	5'-Guanylic acid	85-32-5
T19346	5'-Guanylic acid (5'-guanosine monophosphate) is involved in several metabolic disorders, including AICA-ribosiduria pathway, adenosine deaminase deficiency,aden...
T14063	7α,25-Dihydroxycholesterol	64907-22-8
T14063	7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholes...
T29011	Triiodothyronine Sulfate	31135-55-4
T29011	Triiodothyronine Sulfate is a prodrug to the Conventional Hormone Therapy of Hypothyroidism. Triiodothyronine sulfate is the main metabolite of thyroid hormone t...
T4233	Cysteinylglycine	19246-18-5
T4233	Cysteinylglycine (Cys-Gly), is a biologically important compound since it is formed during the γ-glutamyl cycle. It is a L-cysteinyl peptide, that can be used in...
T7475	S-Adenosyl-L-methionine	29908-03-0	98%
T7475	S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
T40870	Leukotriene E4	75715-89-8	98%
T40870	Leukotriene E4 (LTE4) (LTE4) is produced by the action of dipeptidyl peptidase on LTD4 and is a component of the Slow Reactive Substance of Anaphylaxis (SRS-A).L...
T37961	P-Tolualdehyde	104-87-0	98%
T37961	p-Tolualdehyde is a RIFM flavor that shows inhibition of mushroom tyrosinase.
T77988	Phenyl sulfate	937-34-8	98%
T77988	Phenyl sulfate, an orally active metabolite derived from gut microbiota, induces albuminuria and podocyte damage in diabetes experimental models. It serves as a ...
T78225	3-Butynoic acid	2345-51-9	98%
T78225	3-Butynoic acid is a potent inhibitor of acyl CoA dehydrogenase, a substrate for the Zn-dependent flavoproteinase D-lactate dehydrogenase, and can be used to stu...
T78364	Alanine aminotransferase	9000-86-6	98%
T78364	Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-glutam...
T78466	Erythronic acid potassium		98%
T78466	Potassium erythronate is an intrinsic carbohydrate metabolite utilized in researching metabolic diseases. It significantly influences the development and mitigat...
T78471	α,α-Trehalose 6-phosphate potassium	136632-28-5	98%
T78471	α,α-Trehalose 6-phosphate (Tre6P) potassium is an intrinsic 6-phosphate derivative of α,α′-trehalose and acts as an intermediary metabolite. It undergoes enzymat...
T78474	6PPD-Q	2754428-18-5	98%
T78474	6PPD-Quinone (6PPD-Q) is an endogenous metabolite present in human urine and prevalent in the environment [1].