T4123 |
LYN-1604
|
2088939-99-3
|
98%
|
|
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
|
T15412 |
GPP78
|
1202580-59-3
|
98%
|
|
GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion). GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y ...
|
TN3806 |
Dehydroglyasperin C
|
199331-35-6
|
98%
|
|
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
|
T64374 |
QN523
|
878581-60-3
|
98%
|
|
QN523 represents a novel scaffold with drug-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 shows significant in ...
|
TN4064 |
Flavoglaucin
|
523-73-9
|
98%
|
|
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
|
T6806 |
Cilengitide TFA
|
199807-35-7
|
98%
|
|
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectiv...
|
T10247 |
Adenosine 5′-diphosphoribose sodium
|
68414-18-6
|
98%
|
|
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a NAD+ metabolite. It is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel...
|
T6036 |
Brivanib
|
649735-46-6
|
98%
|
|
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
|
T0161 |
Pantoprazole Sodium Hydrate
|
164579-32-2
|
98%
|
|
Pantoprazole is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease....
|
T0242L |
Sitagliptin phosphate monohydrate
|
654671-77-9
|
98%
|
|
Sitagliptin phosphate is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.
|
TMA1570 |
Sappanone A
|
102067-84-5
|
98%
|
|
Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. It exerts its anti-inflammatory effect by modulating the Nrf2 ...
|
TN4213 |
Hirsutenone
|
41137-87-5
|
98%
|
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
|
T35329 |
EAD1
|
1644388-26-0
|
98%
|
|
|
T6314 |
(R)-(-)-Gossypol
|
90141-22-3
|
98%
|
|
AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM.
|
T8156 |
Saquinavir mesylate
|
149845-06-7
|
98%
|
|
Saquinavir mesylate is an Inhibitor of HIV Proteaseused in antiretroviral therapy
|
T15378 |
Gemcitabine elaidate
|
210829-30-4
|
98%
|
|
Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential ...
|
T39705 |
ATG7-IN-1
|
2226229-87-2
|
98%
|
|
ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.
|
T6085 |
PF-543
|
1415562-82-1
|
98%
|
|
PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
|
TQ0215 |
Salinomycin sodium salt
|
55721-31-8
|
98%
|
|
Salinomycin sodium salt, an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
|
TQ0258 |
Corynoxine B
|
17391-18-3
|
98%
|
|
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
|