15(s)hete methyl ester

15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE , a major arachidonic acid metabolite from the 15-lipoxygenase pathway. Methyl esters of lipids are commonly used in formulations of nutritional supplements.

S-Methyl methanesulfonothioate is a biological raw material with cytotoxicity and potential antimicrobial activity for the study of Pseudomonas aeruginosa infections.

5,6-DIAMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER is a useful organic compound for research related to life sciences. The catalog number is T9829 and the CAS number is 104685-76-9.

Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.

(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) is a potential inhibitor of the mitogen-activated phosphor kinase pathway and an anti-inflammatory agent first isolated from the medicinal plant S. tuberosa. Additionally, it shows promising anthelmintic activity against Haemonchus contortus.

Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a linker; notably, one ligand interacts with the VHL portion.

Azilsartan Methyl Ester is an angiotensin II receptor antagonist. Azilsartan Methyl Ester inhibits specific binding of [125I]AII (0.2 nM) to bovine adrenal cortex with IC50 value is 0.44uM.

L-Cysteine methyl ester hydrochloride (L-Cysteine methyl ester hydrochloride (Acdrile)) is an antitussive and an expectorant agent, used to relieve breathing difficulties caused by mucus.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

Methyl 2-(4-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenoxy)propanoate is a selective herbicide, an inhibitor of fatty acid synthesis, and has a systemic effect. After the stem and leaves are treated, it is quickly absorbed by weeds and transmitted to the whole plant, hydrolyzed into acid, and inhibits the growth of root and stem meristems, resulting in death. For soybean, cotton, peanut, rape, nursery, flax, and other broad-leaved crops to control crabgrass, kangaroo, beef tendon grass, barnyard grass, foxtail, chinensis and other annual grass weeds and bermudagrass, imperatae, etc. ineffective against broadleaf grasses and sedges.

NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hypertension.

6-Bromo-1H-indole-3-acetic acid methyl ester (Methyl 6-Bromoindole-3-acetate) is a marine derived natural products found in Pseudosuberites hyalinus.

Oleoside 11-methyl ester (Methyloleoside) is a natural product.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

Oseltamivir acid methyl ester hydrochloride is a precursor form of oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid converted by carboxylesterase 1 (CES1).

L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that exhibits cytotoxicity towards natural killer cells and CD4+ and CD8+ T lymphocytes.

CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.

Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling.

Dihomo-γ-Linolenic acid methyl ester is the methyl ester form of Dihomo-γ-Linolenic acid which has anti-inflammatory and anti-proliferative effects.

Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac . It is more soluble than diclofenac acid in isopropylmyristate. Diclofenac methyl ester does not permeate human epidermal membranes in vitro.

Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from  rheumatoid arthritis (RA) synovial cells.

Carbamic acid, N-mercapto-N-methyl-, m-isopropylphenyl ester is a bioactive chemical.

15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. The biosynthesis of 15-HEPE from EPA in guinea pig epidermal enzyme preparations has been documented. 15(S)-HEPE generated by soybean lipoxygenation of EPA inhibits RBL-1 cell 5-LO with an IC50 value of 28 μM.

Phosphorodithioic acid, S-(2-butylthioethyl) O,O-diethyl ester is a bioactive chemical.

11(S)-HETE, an (S) enantiomer of 11(R)-HETE and a type of oxylipin, is non-enzymatically synthesized from arachidonic acid. Compared to its counterpart, 11(S)-HETE levels are found to be elevated in both isolated human plasma and serum, as well as in LPS-stimulated isolated human plasma. Notably, patients with allergic rhinitis exhibit a decrease in 11(S)-HETE levels in their serum following one year of double-mite subcutaneous immunotherapy (DM-SCIT), correlating with an enhanced quality of life, particularly in aspects related to rhinoconjunctivitis.

Mead acid, a 20-carbon ω-9 polyunsaturated fatty acid, experiences elevated levels in human plasma under conditions of essential fatty acid deficiency. As 1,25(Z),8(Z),11(Z)-Eicosatrienoic Acid methyl ester (Mead acid methyl ester), it frequently serves as a standard for fatty acid analysis, particularly after fatty acids have been transesterified into methyl esters.

15-Hydroxy Pentadecanoic Acid Methyl Ester is a hydroxylated fatty acid methyl ester (FAME) crucial for synthesizing musk-odored macrocyclic lactones, specifically cyclopentadecanolide and exaltolide [Matreya, LLC. Catalog No. 1882].

14S(15R)-EET methyl ester, an oxylipin derived from arachidonic acid through cytochrome P450 metabolism, demonstrates specific biological activities. It exhibits affinity for isolated guinea pig monocytes, evidenced by a competitive binding assay with a Ki value of 612.5 nM using [3H]14(15)-EET. This compound notably enhances the dilation of precontracted isolated canine epicardial arterioles (EC50= 4 pM) and denuded porcine subepicardial arterioles (EC50= 3 pM), indicating potent vasodilatory effects. Unlike its isomer 14R(15S)-EET, 14S(15R)-EET methyl ester does not inhibit COX activity in enzyme assays or affect isolated platelets, highlighting its distinct functional profile.

10-Methyl palmitic acid methyl ester is a methylated derivative of fatty acid methyl ester, identified in glycolipid analogs with cyclitol from P. crassa. [Matreya, LLC. Catalog No. 1792]

5-Fluorouracil-1-yl acetic acid methyl ester is a PNA-related Derivative.

Pyrocincholic acid methyl ester is a natural product for research related to life sciences. The catalog number is TN4869 and the CAS number is 107160-24-7.

Carbanilic acid, m-((hexyloxy)methyl)-, 2-piperidinoethyl ester, hydrochloride is a bioactive chemical.

(S)-4-(Amino(carboxy)methyl)-3-methylbenzoic acid hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64800.

Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to be determined. 1.Serhan, C.N., Gotlinger, K., Hong, S., et al.Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienesJ. Immunol.176(3)1848-1859(2006) 2.Ariel, A., and Serhan, C.N.Resolvins and protectins in the termination program of acute inflammationTRENDS in Immunology28(4)176-183(2007) 3.Schwab, J.M., Chiang, N., Arita, M., et al.Resolvin E1 and protectin D1 activate inflammation-resolution programmesNature447(7146)869-874(2007)

(2R)-1-Triphenylmethyl-2-pyrrolidinecarboxylic acid methyl ester bolongs toIntermediates and Building Blocks - Amino acid.

6-Mthyluracil-1-yl acetic acid methyl ester is a PNA-related Derivative.

Carbamic acid, methyl(phenylthio)-, m-isopropylphenyl ester is a bioactive chemical.

Carbonic acid, (3-iodophenyl)methyl octyl ester is a bioactive chemical.

15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.

Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.

Myristoleic Acid Methyl Ester is a natural product.

5-Trifluoromethyluracil-1-yl acetic acid methyl ester is a PNA-related Derivative.

Carbanilic acid, m-hydroxy-N-methyl-, methyl ester, dimethylcarbamate (ester) is a bioactive chemical.

Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).

15(S)-Fluprostenol, an isomer of the FP receptor agonist fluprostenol, serves as a potential active metabolite of 15(S)-fluprostenol isopropyl ester. It can function as an agonist at FP receptors, though with lower potency compared to its 15(R) epimer, fluprostenol.

Heneicosapentaenoic Acid (HPA) is a fatty acid found in small amounts in Bryopsis pennata Lamouroux green algae and fish oils, with a structure similar to eicosapentaenoic acid (EPA), but with an additional carbon at the carboxyl end, resulting in the first double bond being in the Δ6 position. HPA is important for researching the impact of double bond positions in n-3 fatty acids, as it integrates into phospholipids and triacylglycerol in vivo as effectively as EPA and docosahexaenoic acid (DHA), while strongly inhibiting the synthesis of arachidonic acid from linoleic acid. Despite being a poor substrate for prostaglandin H (PGH) synthase and 5-lipoxygenase, HPA can rapidly deactivate PGH synthase. HPA methyl ester, in certain formulations, acts as a prodrug to enhance cellular uptake of HPA before being converted into free acid by esterases, and serves as a useful reference standard.

10(E),12(Z)-Conjugated linoleic acid methyl ester serves as a standard for quantifying 10(E),12(Z)-conjugated linoleic acid in L. plantarum culture samples. [Matreya, LLC. Catalog No. 1254]

(S)-Methyl 2-amino-2-cyclopentylacetate hydrochloride, catalog number T65272 and CAS number 14328-62-2, is a valuable organic compound for life sciences research.