T28001 |
MDK-6983
|
MDK6983 , MDK-6983 , Autophagy inhibitor 6k , Compound 6k |
Autophagy
|
|
MDK-6983 is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells. |
T35329L |
EAD1 HCl
|
EAD1 HCL(1644388-26-0 Free base) |
Apoptosis
,
Autophagy
|
|
EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL a... |
T33296 |
Merodantoin
|
|
Apoptosis
|
|
Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin tar... |
T40130 |
Nur77 modulator 1
|
|
Others
|
|
Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-c... |
T38861L |
Tat-beclin 1 acetate
|
Tat-beclin 1 acetate(1423821-88-8 free base) |
HIV Protease
,
Autophagy
|
|
Tat-beclin 1 acetate is a potent inducer of autophagy and interacts with the negative regulator of autophagy, GAPR-1. Ta... |
T36994 |
MRT 67307 dihydrochloride
|
|
SIK
|
|
MRT 67307 dihydrochloride is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively. MRT67307 ... |
T60202 |
MMRi62
|
7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol |
Ferroptosis
|
|
MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-inde... |
T5211 |
NSC 185058
|
NSC185058 |
Cysteine Protease
,
Autophagy
|
|
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity. |
T5793 |
Britannin
|
|
Apoptosis
,
Autophagy
,
AMPK
|
|
Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pat... |
T5172 |
AZ304
|
|
c-Fms
,
Raf
,
p38 MAPK
,
Autophagy
|
|
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (I... |
T3800 |
Typhaneoside
|
Aervitrin |
Others
,
Autophagy
|
|
Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Sha... |
T1131 |
Ivermectin
|
MK-933 |
GluCls
,
P2X Receptor
,
Mitophagy
,
SARS-CoV
,
HIV Protease
,
Antibiotic
,
Parasite
,
Autophagy
,
HSV
|
|
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity. |
T1795 |
Carfilzomib
|
PR-171 |
Proteasome
,
Apoptosis
,
Autophagy
|
|
Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent that is used in treatment of refractory mul... |
T4121 |
Bicyclol
|
SY801 |
HBV
,
Autophagy
|
|
Bicyclol(SY 801) is an anti-hepatitis drug. Oral administration of bicyclol normalizes the elevated serum transaminases ... |
T1076 |
Dexamethasone
|
MK 125 , Hexadecadrol , Prednisolone F , NSC 34521 |
Mitophagy
,
Glucocorticoid Receptor
,
IL Receptor
,
SARS-CoV
,
Autophagy
,
Complement System
,
Antibacterial
,
Antibiotic
|
|
Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exo... |
T9902 |
Atezolizumab
|
|
Apoptosis
,
Autophagy
,
PD-1/PD-L1
|
|
Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD... |
TP1072 |
Valinomycin
|
NSC 122023 |
PTEN
,
Apoptosis
,
Antibiotic
,
Antibacterial
,
Autophagy
|
|
Valinomycin is a dodecadepsipeptide antibiotic, which is obtained from several Streptomyces strains. Valinomycin functio... |
T2926 |
Schizandrin A
|
|
P450
,
Virus Protease
,
Autophagy
|
|
|
T1668 |
Vinblastine sulfate
|
NSC49842 , Vincaleukoblastine sulfate salt |
Microtubule Associated
,
AChR
,
Autophagy
|
|
Vinblastine sulfate can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM). |
T5689 |
20-DEOXYINGENOL
|
|
Others
,
Autophagy
|
|
20-DEOXYINGENOL is a natual product. |