Search Result

Search Results for "autophagy"

Targets

Libraries

Autophagy Compound Library AMPK-Targeted Compound Library Traditional Chinese Medicine Monomer Library Chinese Pharmacopoeia Natural Product Library Glutamine Metabolism Compound Library

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Compounds

Cat No.	Product Name
T28001	MDK-6983	MDK6983 , MDK-6983 , Autophagy inhibitor 6k , Compound 6k	Autophagy
	MDK-6983 is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.		Autophagy
T35329L	EAD1 HCl	EAD1 HCL(1644388-26-0 Free base)	Apoptosis , Autophagy
	EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL a...		Apoptosis , Autophagy
T33296	Merodantoin		Apoptosis
	Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin tar...		Apoptosis
T40130	Nur77 modulator 1		Others
	Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-c...		Others
T38861L	Tat-beclin 1 acetate	Tat-beclin 1 acetate(1423821-88-8 free base)	HIV Protease , Autophagy
	Tat-beclin 1 acetate is a potent inducer of autophagy and interacts with the negative regulator of autophagy, GAPR-1. Ta...		HIV Protease , Autophagy
T36994	MRT 67307 dihydrochloride		SIK
	MRT 67307 dihydrochloride is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively. MRT67307 ...		SIK
T60202	MMRi62	7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol	Ferroptosis
	MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-inde...		Ferroptosis
T5211	NSC 185058	NSC185058	Cysteine Protease , Autophagy
	NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.		Cysteine Protease , Autophagy
T5793	Britannin		Apoptosis , Autophagy , AMPK
	Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pat...		Apoptosis , Autophagy , AMPK
T5172	AZ304		c-Fms , Raf , p38 MAPK , Autophagy
	AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (I...		c-Fms , Raf , p38 MAPK , Autophagy
T3800	Typhaneoside	Aervitrin	Others , Autophagy
	Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Sha...		Others , Autophagy
T1131	Ivermectin	MK-933	GluCls , P2X Receptor , Mitophagy , SARS-CoV , HIV Protease , Antibiotic , Parasite , Autophagy , HSV
	Ivermectin is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
T1795	Carfilzomib	PR-171	Proteasome , Apoptosis , Autophagy
	Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent that is used in treatment of refractory mul...		Proteasome , Apoptosis , Autophagy
T4121	Bicyclol	SY801	HBV , Autophagy
	Bicyclol(SY 801) is an anti-hepatitis drug. Oral administration of bicyclol normalizes the elevated serum transaminases ...		HBV , Autophagy
T1076	Dexamethasone	MK 125 , Hexadecadrol , Prednisolone F , NSC 34521	Mitophagy , Glucocorticoid Receptor , IL Receptor , SARS-CoV , Autophagy , Complement System , Antibacterial , Antibiotic
	Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exo...
T9902	Atezolizumab		Apoptosis , Autophagy , PD-1/PD-L1
	Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD...		Apoptosis , Autophagy , PD-1/PD-L1
TP1072	Valinomycin	NSC 122023	PTEN , Apoptosis , Antibiotic , Antibacterial , Autophagy
	Valinomycin is a dodecadepsipeptide antibiotic, which is obtained from several Streptomyces strains. Valinomycin functio...		PTEN , Apoptosis , Antibiotic , Antibacterial , Autophagy
T2926	Schizandrin A		P450 , Virus Protease , Autophagy
			P450 , Virus Protease , Autophagy
T1668	Vinblastine sulfate	NSC49842 , Vincaleukoblastine sulfate salt	Microtubule Associated , AChR , Autophagy
	Vinblastine sulfate can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).		Microtubule Associated , AChR , Autophagy
T5689	20-DEOXYINGENOL		Others , Autophagy
	20-DEOXYINGENOL is a natual product.		Others , Autophagy