3b-hydroxy-5-cholenoic acid

3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin

Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma.

5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.

3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyrosine metabolism. 3-Hydroxyphenylace

(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when blood glucose is low.

2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease.

(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor. (E)-3-(4-Methoxyphenyl)acrylic acid has hepatoprotective activity, antiamnesic activity, enhances cognitive effects, and can be used to lower blood pressure sugar.

3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. Beta-hydroxybutyrate is a typical pa

5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthylic acid and L-glutamine; which is catalyzed by the enzyme GMP synthase [glutamine-hydrolyzing]. In addition, Guanosine triphosphate and guanosine monophosphate can be biosynthesized from diguanosine tetraphosphate; which is catalyzed by the enzyme bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin action pathway, the telithromycin action pathway, the tobramycin action pathway, and the erythromycin action pathway. Guanosine monophosphate is also involved in several metabolic disorders, some of which include the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria (D and L form) pathway. Outside of the human body, guanosine monophosphate can be found in a number of food items such as onion-family vegetables, millet, chinese water chestnut, and red rice. This makes guanosine monophosphate a potential biomarker for the consumption of these food products.

5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission in Crohn's disease.

3-Hydroxy-1-(4-hydroxyphenyl)propan-1-one (3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone) is a natural product derived from plant source.

trans-3-Indoleacrylic acid is one of the endogenous metabolites that inhibits RSL3-induced ferroptosis and can be used to study colorectal cancer.

5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

5-hydroxy-3,7-dimethoxy-2-phenylchromen- (4H-1-Benzopyran-4-one, 5-hydroxy-3,7-dimethoxy-2-phenyl-),a natural product obtained from the resinous exudate of Heliotropium huascoense.

6-Bromo-1H-indole-3-acetic acid methyl ester (Methyl 6-Bromoindole-3-acetate) is a marine derived natural products found in Pseudosuberites hyalinus.

(+)-6-(2-Hydroxy-3-methoxy-3-methylbutyl is a structural isomer of Ent-toddalolactone, which belongs to the coumarin group.

4-Hydroxy-5-methyl-3-furanone (4-Hydroxy-5-methylfuran-3(2H)-one) is a natural product isolated from Eurycotis floridana.

3-Hydroxy-6-methoxyflavone can be used in combination with antibiotics to treat ESKAPE pathogen infections.

Ellagic acid 3-O-α-L-rhamnopyranoside is a natural product found in the tuberous roots of Potentilla anserina.

5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity.

5,6-dibromo-1H-indole-3-carboxylic acid (5,6-dibromo-1H-indole-3-carboxylicAcid) is a marine derived natural products found in Smenospongia sp.

2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)- (Meridianin C) is a marine derived natural products found in Aplidium meridianum.

4-Hydroxy-3-Nitrobenzyl Alcohol (4-(Hydroxymethyl)-2-nitrophenol) is a marine derived natural products found in Phidolopora pacifica.

5-O-Cinnamoylquinic acid is a nature product.

3',5-Di-O-methyl quercetin (3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-methoxy-4H-chromen-4-one) is a flavonoid natural product.

3-Feruloyl-4-caffeoylquinic acid is a chlorogenic acid isomer. Chlorogenic acids are relevant coffee quality markers, taste, and aroma precursors as well as important bioactive compounds.

2,3-dihydroxy-3-methylbutanoic acid is a natural metabolite of the branched-chain amino acid leucine. It acts by activating the mTOR signaling pathway to promote the synthesis of new muscle proteins and reduce the breakdown of existing proteins, thereby increasing muscle mass and improving recovery from exercise.

6-Bromoindole-3-carboxylic acid (ZINC2547985) is a marine derived natural products found in Pseudosuberites hyalinus.

Methyl 5-hydroxy-1H-indole-3-carboxylate (5-hydroxy-1H-indole-3-carboxylic acid methyl ester) is a marine derived natural products found in Hyrtios erectus.

3-Amino-5-Hydroxybenzoic Acid (3-amino-5-hydroxy-benzoic acid) is a marine derived natural products found in Salinispora arenicola.

5-Bromo-1H-Indole-3-Carboxylic Acid Methyl Ester (Methyl 5-bromo-1H-indole-3-carboxylate) is a marine derived natural products found in Smenospongia sp.

2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer.

5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione ((4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol) is a marine derived natural products found in Leptopsammia pruvoti.

3-Sulfopropanoic acid, a major metabolite of treprostinil and its prodrug ALZ-801, is an endogenous molecule present in the cerebrospinal fluid (CSF) of AD patients that inhibits the formation of Aβ42 oligomers.

5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.

Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia extract. It plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect

3-Indoleacetic acid (indolylacetic acid) (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.

3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.

3-Hydroxy-4-methoxyacetophenone (Acetoisovanillone) is an active P. spinosa extract. It possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon.

Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo-, a lanosterane-type compound, can be isolated from Tu-Jin-Pi, the root bark of Pseudolarix kaempferi [1].

4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate is an α-arabinopyranosides analogue isolated from the aboveground parts of barley [1].

3-Oxooctadecanoic acid (3-Oxostearic acid), a saturated fatty acid (SFA), serves as an intermediate in fatty acid biosynthesis, being converted from malonic acid through the action of enzyme [1].

Compound 7a, (Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate, is a clerodane diterpene [1].

8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin compound present in Heracleum pyrenaicum Lam.

Isosalvianolic acid B is a natural from Salviae miltiorrhizae

1-Decarboxy-3-oxo-ceanothic acid shows in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, the cytotoxic effect is mediated, at least in part, by the induction of apoptosis. It shows cytotoxic against OVCAR-3 and HeLa cancer cell line

5-Hydroxy-2′,3,4′,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 µM in the Hoechst 33342 and pheophorbide A assays.

16-hydroxy Hexadecanoic Acid (Juniperic acid) is a compound isolated from the leaves and stems of Arabidopsis thaliana and can be used to prevent, alleviate, or treat metabolic diseases.

7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.