4-hydroxy-3-nitrophenylacetic acid

4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.

(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine. Sinomenine is an alkaloid derived from the Chinese herb Sinomenium acutum (Thunb.) Rehd. et Wils. (9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one exhibits anti-inflammation effects.

4-Chloro-3-(trifluoromethyl)phenyl isocyanate is a biochemical reagent that can be produced by a series of reactions between o-chlorobenzotrifluoride and acetic anhydride.

3-Hydroxyphthalic anhydride is used to synthesize 3-hydroxyphthalic anhydride modified human serum albumin.

3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative. It also has antioxidant properties.

3-Bromo-4-Methoxyphenylacetonitrile (ZINC2565991) is a marine derived natural products found in Aiolochroia crassa.

3-Chlorophenylboronic acid, a phenylboronic acid derivative, is an important intermediate in the synthesis of prolyl hydroxylase inhibitors, and can be used to synthesize a variety of compounds.The IC50 of 3-Chlorophenylboronic acid for lysophospholipase LYPLA2 was 0.418 µM.

Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorders The urinary excretion of Trans-2-butene-1,4-dicarboxylic acid is increased in conditions of augmented mobilization of fatty acids or inhibited fatty acid oxidation.

4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) is antimicrobial compositions comprising a metal salt and a benzoic acid analog.

4-hydroxyphenylacetic acid (parahydroxy phenylacetate) is a major microbiota-derived metabolite of polyphenols. 4-hydroxyphenylacetic acid(p-Hydroxyphenylacetic acid) is involved in the antioxidative action. 4-hydroxyphenylacetic acid(p-Hydroxyphenylacetic acid) induces expression of Nrf2.

3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 3-Methyl-2-oxobutanoic acid is a neurotoxin, an acidogen, and a metabotoxin. A neurotoxin causes damage to nerve cells and nerve tissues. 3-Methyl-2-oxobutanoic acid is a keto-acid, which is a subclass of organic acids. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis.

(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via lactate dehydrogenase. The D-form is derived from bacterial sources, while the L-form is endogenous. Phenyllactate levels are normally very low in blood or urine, but high levels indicate phenylketonuria (PKU) and hyperphenylalaninemia (HPA). PKU is due to a deficiency of phenylalanine hydroxylase (PAH), causing phenylalanine to convert to phenylpyruvic acid rather than tyrosine.

Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.

trans-3-Indoleacrylic acid is one of the endogenous metabolites that inhibits RSL3-induced ferroptosis and can be used to study colorectal cancer.

3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. 3-Ethoxy-3-oxopropanoic acid exists as a solid, soluble (in water), and a weakly acidic compound (based on its pKa). 3-Ethoxy-3-oxopropanoic acid has been primarily detected in blood. Within the cell, monoethyl malonic acid is primarily located in the cytoplasm.

3-Methylbut-2-enoic acid (Senecioic acid) appears in the urine of patients with 3-Methylcrotonic aciduria, which is a disorder characterized by urine that contains increased amounts of 3-methylcrotonic acid.

4-(Aminomethyl)benzoic acid (PAMBA), an antifibrinolytic, is an unnatural amino acid derivative.

4-Chloro-3-nitrobenzoic acid is a nitric oxide scavenger and has been used to study the effects of nitric oxide on the cardiovascular system and the effects of nitric oxide on the immune system.

Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is also found to be associated with 3-hyd

4-benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester is a biologically active compound used as an intermediate in the synthesis of a variety of compounds.

4-Biphenylcarboxylic acid is a useful organic compound for research related to life sciences. The catalog number is TPL0366 and the CAS number is 92-92-2.

5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.

4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.

Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) is a solid, water-soluble, weakly acidic nutrition enhancer (based on its pKa). This compound, also known as 2-Hydroxy-4-(methylthio)butanoic acid, has been primarily detected in urine and is mainly located in the cytoplasm and adiposome of cells.

3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. Beta-hydroxybutyrate is a typical pa

3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by immune cells.

4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.

2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is a chemical compound and an isomer of Vanillin. 2-Hydroxy-4-methoxybenzaldehyde(4-Methoxysalicylaldehyde) could be used to synthesis Urolithin M7. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond.

3-Methylsalicylic acid (o-Cresotic acid) is a long-acting salicylate derivative with antilipidemic properties. Hydroxytoluic acid has been shown to lower plasma free fatty acid and cholesterol levels.

3-Indolepropionic acid (Indolepropionic acid) is shown to be a powerful antioxidant with potential in the treatment for Alzheimer’s disease.

(Z)-4-Amino-4-oxobut-2-enoic acid (Maleamic acid) is a valuable compound for research applications.

3-Furanoic acid (3-Carboxyfuran) is an organic acid regularly occurring in the urine of healthy individuals. 3-Furanoic acid (3-Carboxyfuran) is also a compound found in honey and honeydew samples.

4-Methyl-2-oxopentanoic acid is an abnormal metabolite, a neurotoxin and a metabolic toxin.

3-(Methylthio)propionic acid (4-Thiapentanoic acid) is one of the metabolites of methionine (especially of D-methionine). Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly related to the concentration of methionine in the medium. The first intermediate in the pathway may be the keto acid, which is then oxidatively decarboxylated to 3-methylthiopropionic acid.

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one shows antitumor activity in a human colon cancer cell line and may be used to combat thrombosis.

(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor with hepatoprotective, antiamnesic, and cognitive enhancement activities, and it can be used to lower blood pressure sugar.

4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid (SCFA) and a metabolite of 20 alpha-hydroxycholesterol.

2-Methyl-4-pentenoic Acid (2-Methylpent-4-enoic acid) is a branched-chain fatty acid.

3-Methoxybenzoic acid (NSC 27014) is a food additive,and has antibacterial activity.

2-Methyl-2H-indazole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is Fr21265 and the CAS number is 34252-44-3.

4-aminobenzoic acid is an organic acid with UV-absorbing and antifibrotic properties. When exposed to light, 4-aminobenzoic acid absorbs UV light and releases excess energy through a photochemical reaction, which may cause DNA damage.4-aminobenzoic acid also increases oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote serotonin degradation, which in excess may lead to fibrotic Changes.

3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) is an endogenous metabolite excreted in the urine and can serve as an early and sensitive indicator of biotin deficiency.

4-Amino-5-Chloro-2-Methoxybenzoic Acid (Metoclopramide EP Impurity C) is a Metoclopramide metabolite.

3,5-Dibromo-4-methoxybenzoic acid was isolated from the Malagasy sponge Amphimedon sp.

2-Hydroxy-4-methoxybenzoic acid (2-Hydroxy-p-anisic Acid) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 3-(2-hydroxy-4-methoxyphenyl)propanoic acid. It is generated by unspecified-gutmicro enzyme via a beta-oxidation-of-carbxoylic-acid reaction. This beta-oxidation-of-carbxoylic-acid occurs in human gut microbiota.

3-Methyl-2-nitrobenzoic acid is in agricultural chemicals such asWithPreparation in be used as intermediate.

2-(4-Methoxyphenyl)acetic acid, a plasma metabolite, is highly sensitive and specific and can be used as a bioindicator to differentiate non-small cell carcinoma patients from healthy controls.

3-Hydroxybutyric acid (Butanoic acid) (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised in ketosis. In humans, 3-hydroxybutyrate is synthesized in the liver from acetyl-CoA and can be used as an energy source by the brain when blood glucose is low. Blood levels of 3-hydroxybutyric acid levels may be monitored in diabetic patients to look for diabetic ketoacidosis. Persistent mild hyperketonemia is a common finding in newborns. Ketone bodies serve as an indispensable source of energy for extrahepatic tissues, especially the brain and lung of developing mammals. Another important function of ketone bodies is to provide acetoacetyl-CoA and acetyl-CoA for the synthesis of cholesterol, fatty acids, and complex lipids. During the early postnatal period, acetoacetate (AcAc) and beta-hydroxybutyrate are preferred over glucose as substrates for synthesis of phospholipids and sphingolipids in accord with requirements for brain growth and myelination. Thus, during the first 2 weeks of postnatal development, when the accumulation of cholesterol and phospholipids accelerates, the proportion of ketone bodies incorporated into these lipids increases. On the other hand, an increased proportion of ketone bodies is utilized for cerebroside synthesis during the period of active myelination. In the lung, AcAc serves better than glucose as a precursor for the synthesis of lung phospholipids. The synthesized lipids, particularly dipalmitoylphosphatidylcholine, are incorporated into surfactant, and thus have a potential role in supplying adequate surfactant lipids to maintain lung function during the early days of life (PMID: 3884391 ). 3-Hydroxybutyric acid is found to be associated with fumarase deficiency and medium-chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.

Indole-3-carboxylic acid (3-Indoleformic acid) is a normal urinary indolic tryptophan metabolite .

4-Hydroxy-5-methyl-3-furanone (4-Hydroxy-5-methylfuran-3(2H)-one) is a natural product isolated from Eurycotis floridana.