Search Result

Search Results for " dna "

Targets

DNA/RNA Synthesis DNA Methyltransferase DNA Alkylation DNA-PK DNA DNA gyrase DNA Alkylator/Crosslinker Antiviral DNA/RNA Synthesis

1636

Compounds

284

Natural Products

554

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T80644	DNA polymerase-IN-1		Antiviral , DNA/RNA Synthesis
	DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an I...		Antiviral , DNA/RNA Synthesis
T31554	DNA-Spermidine	DA-51,DA 51,DA51,DNA Spermidine
	DNA-spermidine influences the activity of restricted endonuclease from several bacterial species.
T3103	L67	DNA Ligase Inhibitor	DNA , DNA/RNA Synthesis
	L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).		DNA , DNA/RNA Synthesis
T1904	SGI-1027	DNA Methyltransferase Inhibitor II,SGI1027	Apoptosis , DNA Methyltransferase
	SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.		Apoptosis , DNA Methyltransferase
T2433	NU 7026	NU7026,DNA-PK Inhibitor II,LY293646	Apoptosis , ATM/ATR , DNA-PK , PI3K
	NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition against both ATM and ATR.		Apoptosis , ATM/ATR , DNA-PK , PI3K
T27194	DNA Primase Inhibitor-13
	DNA Primase Inhibitor-13 is a novel inhibitor of DNA primase.
T79922	Taq DNA polymerase		DNA/RNA Synthesis
	Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].		DNA/RNA Synthesis
T61937	DNA Gyrase-IN-3
	DNA Gyrase-IN-3 (Compound 28) is an inhibitor of bacterial DNA gyrase B. The IC50 of DNA Gyrase-IN-3 inhibits Escherichia coli DNA rotatase is 5.41-15.64 μM. DNA Gyrase-IN-3 shows anti-tuberculosis and antibacterial acti...
T61857	DNA-PK-IN-4
	DNA-PK-IN-4 (WO2021209055A1, compound 27), an imidazolinone derivative compound, is a highly effective inhibitor of DNA-PK, specifically targeting DNA-PKcs activity. By inhibiting DNA-PKcs, the compound significantly imp...
T62191	DNA-PK-IN-5
	DNA-PK-IN-5 is a potent inhibitor of DNA-PK. DNA-PK-IN-5 inhibits the activity of DNA-PKcs, significantly reduces tumour DNA repair and induces apoptosis. DNA-PK-IN-5 improves the sensitivity of tumour tissue to radiothe...
T62034	DNA-PK-IN-7
	DNA-PK-IN-7 is a potent DNA-PK inhibitor (IC50= 1 nM) (WO2021104277A1, compound 5).
T63395	DNA Gyrase-IN-5
	DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.
T79307	DNA polymerase-IN-2		DNA/RNA Synthesis
	DNA polymerase-IN-2 (Compd 3c), a coumarin derivative, demonstrates inhibitory activity towards Taq DNA polymerase, with an IC50 value of 48.25 μM, and holds potential for application in value-added disease research [1].		DNA/RNA Synthesis
T74338	DNA crosslinker 2 dihydrochloride
	DNA crosslinker 2 (dihydrochloride) is a potent minor groove binder exhibiting a Δ T m of 1.2 °C, indicative of its DNA binding affinity. This compound demonstrates inhibitory activity against cancer cell lines NCI-H460,...
T61633	DNA-PK-IN-2
	DNA-PK-IN-2 is a highly effective inhibitor of DNA-dependent protein kinase (DNA-PK), which is a complex enzyme composed of Ku70/Ku80 heterodimer and DNA-PK catalytic subunit (DNA-PKcs). With its potential applications i...
T62648	DNA-PK-IN-1
	DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.
T61533	DNA-PK-IN-9
	DNA-PK-IN-9 (also known as compound YK6) is a highly potent inhibitor of DNA-dependent protein kinase (DNA-PK), displaying an IC50 value of 10.47 nM. DNA-PK-IN-9 holds significant potential in anticancer research [1].
T63442	DNA Gyrase-IN-2
	DNA Gyrase-IN-2 is a bacterial DNA cyclooxygenase B inhibitor that acts on Escherichia coli DNA cyclooxygenase (IC50: 3.29-10.49 μM) and Mycobacterium tuberculosis DNA cyclooxygenase (IC50: 4.41-5.61 μM), exhibiting anti...
T61370	DNA-PK-IN-6
	DNA-PK-IN-6, a robust DNA-PK inhibitor, effectively hampers the activity of DNA-PKcs, thereby significantly impairing the DNA repair mechanism in tumors and instigating apoptosis in cells. Additionally, DNA-PK-IN-6 ampli...
T60961	LANA-DNA-IN-1
	LANA-DNA-IN-1 is a potent inhibitor of LANA-DNA with IC50 values of 8 μM, 9μM, and 8μM for LBS2, LBS1 and LBS3, respectively. The IC50 value of LANA-DNA-IN-1 against wild-type LANA is 53 μM. LANA-DNA-IN-1 can be used in ...
T61828	DNA-PK-IN-8
	DNA-PK-IN-8 is a potent, selective, and orally active inhibitor of DNA-dependent protein kinase (DNA-PK), demonstrating an IC50 value of 0.8 nM. It displays synergistic antiproliferative effects across various cancer cel...
T78866	DNA Gyrase-IN-9		DNA/RNA Synthesis
	DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase. It exhibits a minimum inhibitory concentration (MIC) of 0.5-2 µg/mL for Gram-positive bacteria inhibition and a minimum bactericidal ...		DNA/RNA Synthesis
T62895	DNA Gyrase-IN-4
	DNA Gyrase-IN-4 (compound 8p) is a potent inhibitor of DNA cyclooxygenase (IC50: 0.13 μM). (MIC: 0.05 μg/ml), Salmonella (MIC: 0.05 μg/ml) and Escherichia coli (MIC: 8 μg/ml).
T63681	DNA Gyrase-IN-1
	DNA Gyrase-IN-1 is a potent and selective DNA promoter inhibitor (IC50: 2.6 μM). DNA Gyrase-IN-1 inhibits Mycobacterium tuberculosis (Mtb) activity well (MIC: 0.49 μM). DNA Gyrase-IN-1 can be used to study tuberculosis.
T74337	DNA crosslinker 1 dihydrochloride
	DNA Crosslinker 1 (dihydrochloride) serves as a potent binder for the DNA minor groove, exhibiting a DNA binding affinity (ΔTm) of 1.1°C. This compound is utilized in research focused on anticancer therapies [1].
T78712	DNA Gyrase-IN-8		DNA/RNA Synthesis
	DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].		DNA/RNA Synthesis
T79165	DNA-PK-IN-10		DNA-PK
	DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].		DNA-PK
T79308	DNA polymerase-IN-3		DNA/RNA Synthesis
	DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in proliferative disease research [1].		DNA/RNA Synthesis
T61751	DNA-PK-IN-3
	DNA-PK-IN-3 is a highly potent inhibitor of DNA-PK. This compound exerts a synergistic effect when combined with radiotherapy and chemotherapy, resulting in enhanced therapeutic outcomes and significant inhibition of tum...
T74339	DNA crosslinker 3 dihydrochloride
	DNA Crosslinker 3 (dihydrochloride) (Compound 1) is a potent minor groove binder, exhibiting a DNA binding affinity (ΔTm) of 1.4°C, and serves as a valuable tool in anticancer research [1].
T74340	DNA crosslinker 4 dihydrochloride
	DNA Crosslinker 4 (dihydrochloride) is a potent binder of the DNA minor groove with inhibitory effects on cancer cell lines NCI-H460, A2780, and MCF-7. It is utilized in research for anticancer applications [1].
T81953	LANA-DNA-IN-2
	Compound 20, also known as LANA-DNA-IN-2, is an inhibitor of the interaction between latency-associated nuclear antigen (LANA) and DNA. It is employed in the study of Kaposi’s sarcoma-associated herpesvirus (KSHV) infect...
T82536	DNA polymerase-IN-4
	DNA polymerase-IN-4 (Compd 5c), a coumarin derivative, exhibits antiretroviral activity, achieving an IC50 of 134.22 μM [1].
T74848	DNA Gyrase-IN-6
	Antibacterial agent 138, a benzothiazole inhibitor, targets bacterial DNA gyrase and topoisomerase IV, exhibiting both favorable solubility and plasma protein binding. It demonstrates antibacterial activity against Gram-...
T79240	DNA gyrase B-IN-2
	DNA gyrase B-IN-2 (Compound E), a 2-aminobenzothiazole derivative, serves as a potent inhibitor of DNA gyrase B with substantial efficacy against ESKAPE pathogens. The compound exhibits potent nanomolar-range inhibition ...
T63360	DNA topoisomerase II inhibitor 1
	DNA topoisomerase II inhibitor 1 is a potent inhibitor of DNA topoisomerase II that arrests the cell cycle in sub-G1 phase and induces apoptosis with anti-value-added effects.
T64012	DNA gyrase B-IN-1
	DNA gyrase B-IN-1 is a potent inhibitor of DNA gyrase B, exhibiting good binding affinity and stability. DNA gyrase B-IN-1 inhibits P. aeruginosa/i> DNA gyrase B (IC50: 2.2 μM).
T78776	DNA gyrase B-IN-3		DNA/RNA Synthesis
	DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against Gram-positive strains [1].		DNA/RNA Synthesis
T62389	14α-Demethylase/DNA Gyrase-IN-2
	14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.
T62792	14α-Demethylase/DNA Gyrase-IN-1
	14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.
T74613	G-quadruplex DNA fluorescence probe 1
	Compound E1, also known as G-quadruplex DNA fluorescence probe 1, is a selective fluorescent probe targeting G-quadruplex DNA. It possesses the ability to penetrate membranes and enter living cells, demonstrating low cyt...
T8873	Bractoppin		Others , DNA/RNA Synthesis
	Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...		Others , DNA/RNA Synthesis
T4517	L189		DNA , DNA/RNA Synthesis
	L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).		DNA , DNA/RNA Synthesis
T12019	Methylproamine		Others
	Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.		Others
T11469	GSK-3484862		DNA Methyltransferase
	GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.		DNA Methyltransferase
T0164	Oxaliplatin	L-OHP	DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
	Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop...
T36757	DMT-dU-CE Phosphoramidite		DNA/RNA Synthesis
	DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.		DNA/RNA Synthesis
T15080	DC-05		DNA Methyltransferase , Histone Methyltransferase
	DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).		DNA Methyltransferase , Histone Methyltransferase
T15789	LTURM34		DNA-PK , PI3K , PI4K
	LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K .		DNA-PK , PI3K , PI4K
T4339	YU238259		DNA-PK , Others
	YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.		DNA-PK , Others

Compounds

DNA polymerase-IN-1

T80644

Synonym:

Target: Antiviral, DNA/RNA Synthesis

DNA-Spermidine

T31554

Synonym: DA-51,DA 51,DA51,DNA Spermidine

Target:

L67

T3103

Synonym: DNA Ligase Inhibitor

Target: DNA, DNA/RNA Synthesis

SGI-1027

T1904

Synonym: DNA Methyltransferase Inhibitor II,SGI1027

Target: Apoptosis, DNA Methyltransferase

NU 7026

T2433

Synonym: NU7026,DNA-PK Inhibitor II,LY293646

Target: Apoptosis, ATM/ATR, DNA-PK, PI3K

DNA Primase Inhibitor-13

Target: DNA/RNA Synthesis

DNA polymerase-IN-2

T79307

Synonym:

Target: DNA/RNA Synthesis

DNA crosslinker 2 dihydrochloride

Target: DNA/RNA Synthesis

DNA crosslinker 1 dihydrochloride

Target: DNA/RNA Synthesis

DNA polymerase-IN-3

T79308

Synonym:

Target: DNA/RNA Synthesis

DNA crosslinker 3 dihydrochloride

T74339

Synonym:

Target:

DNA crosslinker 4 dihydrochloride

DNA polymerase-IN-4

DNA topoisomerase II inhibitor 1

Target: DNA/RNA Synthesis

14α-Demethylase/DNA Gyrase-IN-2

T62389

Synonym:

Target:

14α-Demethylase/DNA Gyrase-IN-1

T62792

Synonym:

Target:

G-quadruplex DNA fluorescence probe 1

Target: Others, DNA/RNA Synthesis

L189

T4517

Synonym:

Target: DNA, DNA/RNA Synthesis

Target: DNA Methyltransferase

Oxaliplatin

T0164

Synonym: L-OHP

Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy

DMT-dU-CE Phosphoramidite

T36757

Synonym:

Target: DNA/RNA Synthesis

DC-05

T15080

Synonym:

Target: DNA Methyltransferase, Histone Methyltransferase

LTURM34

T15789

Synonym:

Target: DNA-PK, PI3K, PI4K

YU238259

T4339

Synonym:

Target: DNA-PK, Others

Cat No.	Product Name	Synonyms	Targets
T13592	Calf thymus DNA	DNA from calf thymus, Thymonucleic acid	DNA/RNA Synthesis
	Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, which can be widely used in the study of DNA binding anticancer agents and ...		DNA/RNA Synthesis
T21498	Phleomycin		DNA/RNA Synthesis , Antibacterial , Antibiotic
	Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T37101	1-Hydroxyanthraquinone		DNA/RNA Synthesis
	1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.		DNA/RNA Synthesis
T1068	Dithranol	1,8,9-trihydroxyanthracene,cignoline,Anthralin	Others , DNA/RNA Synthesis
	Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.		Others , DNA/RNA Synthesis
T7520	Deoxycytidine triphosphate		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite
	Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T13969	Xanthopterin (hydrate)		Others , DNA/RNA Synthesis
	Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.		Others , DNA/RNA Synthesis
TN2132	Quinizarin	1,4-Dihydroxyanthraquinone	Others , DNA/RNA Synthesis , Antifungal
	Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product		Others , DNA/RNA Synthesis , Antifungal
T40179	Sodium Camptothecin		DNA/RNA Synthesis
	Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i...		DNA/RNA Synthesis
T2S1635	3-Isomangostin		MTH1
	3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...		MTH1
T12651	Rabdosiin	(+)-Rabdosiin	Others
	Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.		Others
T0064	Adenine	Vitamin B4,6-Aminopurine	DNA/RNA Synthesis , Endogenous Metabolite , AChR
	Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic...		DNA/RNA Synthesis , Endogenous Metabolite , AChR
TWP2911	Thymidine	5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin	Others , DNA/RNA Synthesis , Endogenous Metabolite
	1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.		Others , DNA/RNA Synthesis , Endogenous Metabolite
TN1134	Euscaphic acid		Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
	Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T5270	5-Methylcytosine		Others , DNA/RNA Synthesis , Endogenous Metabolite
	5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...		Others , DNA/RNA Synthesis , Endogenous Metabolite
T5901	3-Hydroxy-2-methylpyridine		Others
	3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.		Others
T3606	γ-Oryzanol	Gamma-Oryzanol,Oliver,Gammariza	DNA Methyltransferase
	γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b...		DNA Methyltransferase
T3717	Hinokitiol	4-Isopropyltropolone,β-thujaplicin	DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2
	Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent...
T7457	5-Methyl-2'-deoxycytidine	5-Methyldeoxycytidine,5MedCyd	DNA Methyltransferase , Endogenous Metabolite
	5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.		DNA Methyltransferase , Endogenous Metabolite
T6567	Levofloxacin	Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin	Topoisomerase , Antibacterial , Antibiotic
	Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.		Topoisomerase , Antibacterial , Antibiotic
TN3110	5-Geranoxy-7-methoxycoumarin		Anti-infection , Antibacterial , Antifungal
	5-Geranoxy-7-methoxycoumarin shows antifungal activity.		Anti-infection , Antibacterial , Antifungal
TQ0184	Chebulinic acid		ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
	Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T35455	N-Nitrosodiethylamine	Diethylnitrosamine,NDEA	DNA/RNA Synthesis
	N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso...		DNA/RNA Synthesis
T6S0232	Eriodictyol	Huazhongilexone	Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite
	1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3....
T1508	Decitabine	Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine	Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase
	Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis...
T6225	Adenine hydrochloride	Adenine HCl,6-Aminopurine hydrochloride	DNA/RNA Synthesis , Endogenous Metabolite
	Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.		DNA/RNA Synthesis , Endogenous Metabolite
T0974	Novobiocin Sodium	Albamycinsodium,Cathomycin,Albamycin	Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
	Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T1507	Streptozocin	STZ,Streptozotocin,NSC-85998,U 9889	DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy
	Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. Th...
T6369	Adenine hemisulfate	Diadenine sulphate,Adenine sulfate,Adeninsulfat	DNA/RNA Synthesis , Endogenous Metabolite
	Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.		DNA/RNA Synthesis , Endogenous Metabolite
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T1339	5-Azacytidine	Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC	Nucleoside Antimetabolite/Analog , DNA Methyltransferase , Antibacterial , Antibiotic , Autophagy
	5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autopha...
T3332	Isosteviol	(-)-Isosteviol	IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
	Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
T13229	Tunicamycin		Influenza Virus , Antibacterial , Antibiotic , Antifungal
	Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity...		Influenza Virus , Antibacterial , Antibiotic , Antifungal
TN1637	Eurycomalactone		Anti-infection , NF-κB
	Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-in...		Anti-infection , NF-κB
T4593	ISOPIMPINELLIN	5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen	Antiviral , DNA/RNA Synthesis , Parasite
	Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity.		Antiviral , DNA/RNA Synthesis , Parasite
T9715	Aplidine		SARS-CoV , DNA/RNA Synthesis
	Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).		SARS-CoV , DNA/RNA Synthesis
T2998	Dihydromyricetin	Ampelopsin,Ampeloptin	Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy
	Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy...
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
T6995	Ochromycinone	STA 21,STA21,STA-21	Antibacterial , STAT
	Ochromycinone (STA 21) is a selective STAT3 inhibitor.		Antibacterial , STAT
T4558	Trioxsalen	Trimethylpsoralen,Trioxysalen,Trisoralen	DNA Alkylator/Crosslinker , DHFR
	Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, wh...		DNA Alkylator/Crosslinker , DHFR
T13791	N2-methylguanine		DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial
	N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.		DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial
T7004	Tubercidin	Sparsomycin A,7-Deazaadenosine	Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib...
T6758	Anisomycin	Flagecidin,NSC 76712,Wuningmeisu C	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK
	Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
T6116	Bleomycin Sulfate	Blenoxane,NSC125066	DNA/RNA Synthesis , Antibiotic
	Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.		DNA/RNA Synthesis , Antibiotic
T5368	Eicosapentaenoic Acid		Histone Demethylase , Others , Endogenous Metabolite
	Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms.		Histone Demethylase , Others , Endogenous Metabolite
T40426	Cytidine 5'-diphosphate trisodium salt	CDP	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp...		Others
T0909	Nalidixic acid	NSC-82174	Topoisomerase , Antibacterial , Antibiotic
	Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.		Topoisomerase , Antibacterial , Antibiotic
TN1097	β-Boswellic acid	Beta-boswellic acid	Lipoxygenase , DNA/RNA Synthesis
	β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities.		Lipoxygenase , DNA/RNA Synthesis
T8130	Ciprofloxacin hydrochloride monohydrate	Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan	Antibacterial , Antibiotic
	Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic,is an antibiotic used to treat a number of bacterial infections		Antibacterial , Antibiotic
T7174	Urolithin A		Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite
	Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
------------------------ More ------------------------

Natural Products

Calf thymus DNA

T13592

Synonym: DNA from calf thymus, Thymonucleic acid

Target: DNA/RNA Synthesis

Phleomycin

T21498

Synonym:

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

1-Hydroxyanthraquinone

T37101

Synonym:

Target: DNA/RNA Synthesis

Dithranol

T1068

Synonym: 1,8,9-trihydroxyanthracene,cignoline,Anthralin

Target: Others, DNA/RNA Synthesis

Deoxycytidine triphosphate

T7520

Synonym:

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Xanthopterin (hydrate)

T13969

Synonym:

Target: Others, DNA/RNA Synthesis

Quinizarin

TN2132

Synonym: 1,4-Dihydroxyanthraquinone

Target: Others, DNA/RNA Synthesis, Antifungal

Sodium Camptothecin

T40179

Synonym:

Target: DNA/RNA Synthesis

Synonym: (+)-Rabdosiin

Target: Others

Adenine

T0064

Synonym: Vitamin B4,6-Aminopurine

Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR

Thymidine

TWP2911

Synonym: 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Euscaphic acid

TN1134

Synonym:

Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor

5-Methylcytosine

T5270

Synonym:

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

3-Hydroxy-2-methylpyridine

Synonym: Gamma-Oryzanol,Oliver,Gammariza

Target: DNA Methyltransferase

Hinokitiol

T3717

Synonym: 4-Isopropyltropolone,β-thujaplicin

Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2

5-Methyl-2'-deoxycytidine

T7457

Synonym: 5-Methyldeoxycytidine,5MedCyd

Target: DNA Methyltransferase, Endogenous Metabolite

Levofloxacin

T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

5-Geranoxy-7-methoxycoumarin

TN3110

Synonym:

Target: Anti-infection, Antibacterial, Antifungal

Chebulinic acid

TQ0184

Synonym:

Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad

N-Nitrosodiethylamine

T35455

Synonym: Diethylnitrosamine,NDEA

Target: DNA/RNA Synthesis

Eriodictyol

T6S0232

Synonym: Huazhongilexone

Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite

Decitabine

T1508

Synonym: Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase

Adenine hydrochloride

T6225

Synonym: Adenine HCl,6-Aminopurine hydrochloride

Target: DNA/RNA Synthesis, Endogenous Metabolite

Novobiocin Sodium

T0974

Synonym: Albamycinsodium,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

Streptozocin

T1507

Synonym: STZ,Streptozotocin,NSC-85998,U 9889

Target: DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibacterial, Antibiotic, Autophagy

Adenine hemisulfate

T6369

Synonym: Diadenine sulphate,Adenine sulfate,Adeninsulfat

Target: DNA/RNA Synthesis, Endogenous Metabolite

Pseudouridine

T16674

Synonym:

Target: Endogenous Metabolite

5-Azacytidine

T1339

Synonym: Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC

Target: Nucleoside Antimetabolite/Analog, DNA Methyltransferase, Antibacterial, Antibiotic, Autophagy

Isosteviol

T3332

Synonym: (-)-Isosteviol

Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase

Tunicamycin

T13229

Synonym:

Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal

Eurycomalactone

TN1637

Synonym:

Target: Anti-infection, NF-κB

ISOPIMPINELLIN

T4593

Synonym: 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen

Target: Antiviral, DNA/RNA Synthesis, Parasite

Aplidine

T9715

Synonym:

Target: SARS-CoV, DNA/RNA Synthesis

Dihydromyricetin

T2998

Synonym: Ampelopsin,Ampeloptin

Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy

Kamebakaurin

TWS1977

Synonym: Kamebakaurine

Target: NF-κB

Ochromycinone

T6995

Synonym: STA 21,STA21,STA-21

Target: Antibacterial, STAT

Trioxsalen

T4558

Synonym: Trimethylpsoralen,Trioxysalen,Trisoralen

Target: DNA Alkylator/Crosslinker, DHFR

N2-methylguanine

T13791

Synonym:

Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial

Tubercidin

T7004

Synonym: Sparsomycin A,7-Deazaadenosine

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic

Anisomycin

T6758

Synonym: Flagecidin,NSC 76712,Wuningmeisu C

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK

Bleomycin Sulfate

T6116

Synonym: Blenoxane,NSC125066

Target: DNA/RNA Synthesis, Antibiotic

Eicosapentaenoic Acid

T5368

Synonym:

Target: Histone Demethylase, Others, Endogenous Metabolite

Cytidine 5'-diphosphate trisodium salt

Target: Topoisomerase, Antibacterial, Antibiotic

β-Boswellic acid

TN1097

Synonym: Beta-boswellic acid

Target: Lipoxygenase, DNA/RNA Synthesis

Ciprofloxacin hydrochloride monohydrate

T8130

Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan

Target: Antibacterial, Antibiotic

Urolithin A

T7174

Synonym:

Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite

--------- More ---------

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00523	DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc)	Escherichia phage RB69	E. coli
	Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction for proofreadin...
TMPJ-00792	DNA PolymeraseBeta Protein, Human, Recombinant (His)	Human	E. coli
	Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-p...
TMPH-00476	DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc)	Dictyostelium discoideum	E. coli
	DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00611	DNA helicase II Protein, E. coli, Recombinant	E. coli	E. coli
	A helicase with DNA-dependent ATPase activity. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand. Initiates unwinding more efficiently from a nicked substrate than ds duplex DNA. Involved in th...
TMPH-00475	DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His)	Desulfotalea psychrophila	E. coli
	DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His) is expressed in E. coli.
TMPH-00425	DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)	Colwellia psychrerythraea	E. coli
	DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli.
TMPH-00427	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant	Colwellia psychrerythraea	E. coli
	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant is expressed in E. coli.
TMPH-00426	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His)	Colwellia psychrerythraea	E. coli
	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli.
TMPH-00613	DNA polymerase II Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Thought to be involved in DNA repair and/or mutagenesis. Its processivity is enhanced by the beta sliding clamp (dnaN) and clamp loader.
TMPH-03614	DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO)	Synechococcus sp.	E. coli
	DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-00524	ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)	Enterobacteria phage T4	E. coli
	DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule be...
TMPH-00360	DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant	Cenarchaeum symbiosum	E. coli
	Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicativ...
TMPH-03487	DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His)	Serratia marcescens	E. coli
	A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensi...
TMPH-00668	DNA-binding protein HU-alpha Protein, E. coli O157:H7, Recombinant (His & SUMO)	E. coli	E. coli
	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
TMPH-00616	DNA-binding protein H-NS Protein, E. coli, Recombinant (His)	E. coli	E. coli
	A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstrea...
TMPJ-00457	OGG1 Protein, Human, Recombinant	Human	E. coli
	Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamido...
TMPH-00898	Human adenovirus C serotype 5 DNA-binding protein (His)	HAdV-5	Baculovirus
	Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. Also enhances the rate of initiation. Relea...
TMPH-00896	Human adenovirus C serotype 2 DNA-binding protein (His)	HAdV-2	E. coli
	Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. Also enhances the rate of initiation. Relea...
TMPH-03193	Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO)	Pyrococcus furiosus	E. coli
	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DN...
TMPH-00039	Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)	Agrobacterium fabrum	E. coli
	Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence compos...
TMPJ-00872	MGMT Protein, Human, Recombinant (His)	Human	E. coli
	MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs al...
TMPJ-00483	DFF45 Protein, Human, Recombinant (His)	Human	E. coli
	DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF...
TMPY-03601	PDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chapero...
TMPY-02150	GADD45A Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulatio...
TMPJ-00907	GADD45A Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some ...
TMPH-02550	BLM Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction. Participates in DNA replication and repair. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwin...
TMPJ-00711	GADD45G Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript...
TMPY-03655	GADD45G Protein, Human, Recombinant	Human	E. coli
	GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G re...
TMPH-01010	BLM Protein, Human, Recombinant (His)	Human	E. coli
	ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction. Participates in DNA replication and repair. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwin...
TMPH-00525	DsDNA-binding protein A Protein, Enterobacteria phage T4, Recombinant (His & Myc)	Enterobacteria phage T4	E. coli
	May play a role in transcription of several T4 genes. Binds double-stranded DNA and interacts preferentially with T4 late promoter regions.
TMPH-00359	AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)	Caulobacter vibrioides	E. coli
	Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing...
TMPH-00577	AlkB Protein, E. coli, Recombinant (His & Myc & SUMO)	E. coli	E. coli
	Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing...
TMPH-01450	Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His)	HHV-6A	Yeast
	Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His) is expressed in Yeast.
TMPH-02908	AICDA Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (...
TMPH-01235	APOBEC3A Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus...
TMPY-02000	UNG Protein, Human, Recombinant (GST)	Human	E. coli
	Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in t...
TMPJ-00765	TDT Protein, Human, Recombinant (His)	Human	E. coli
	Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a si...
TMPH-01236	DFFB Protein, Human, Recombinant (His)	Human	E. coli
	Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
TMPJ-01061	Nucleobindin-2 Protein, Human, Recombinant	Human	E. coli
	Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulat...
TMPY-02420	HEMK2 Protein, Human, Recombinant (His)	Human	E. coli
	N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to t...
TMPJ-01328	ZBP1 Protein, Human, Recombinant (His)	Human	E. coli
	Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of vir...
TMPH-01091	CHD1L Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catal...
TMPH-01903	APOBEC3C Protein, Human, Recombinant (GST)	Human	E. coli
	APOBEC3C Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-02997	Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)	Mycobacterium smegmatis	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPH-02993	DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc)	Mycobacterium paratuberculosis	E. coli
	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules int...
TMPH-00794	Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)	Helicobacter pylori	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPY-02433	APE1/APEX1 Protein, Human, Recombinant (His)	Human	E. coli
	The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease, DNA 3' repair diest...
TMPJ-00700	GADD45B Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPH-01899	ALKBH5 Protein, Human, Recombinant (His)	Human	E. coli
	Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also deme...
TMPJ-01241	DTD1 Protein, Human, Recombinant (His)	Human	Human Cells
	D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is...
------------------------ More ------------------------

DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc)

TMPH-00523

Species: Escherichia phage RB69

Expression System: E. coli

DNA PolymeraseBeta Protein, Human, Recombinant (His)

TMPJ-00792

Species: Human

Expression System: E. coli

DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc)

TMPH-00476

Species: Dictyostelium discoideum

Expression System: E. coli

DNA helicase II Protein, E. coli, Recombinant

TMPH-00611

Species: E. coli

Expression System: E. coli

DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His)

TMPH-00475

Species: Desulfotalea psychrophila

Expression System: E. coli

DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)

TMPH-00425

Species: Colwellia psychrerythraea

Expression System: E. coli

DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant

TMPH-00427

Species: Colwellia psychrerythraea

Expression System: E. coli

DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His)

TMPH-00426

Species: Colwellia psychrerythraea

Expression System: E. coli

DNA polymerase II Protein, E. coli, Recombinant (His & Myc)

TMPH-00613

Species: E. coli

Expression System: E. coli

DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO)

TMPH-03614

Species: Synechococcus sp.

Expression System: E. coli

ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)

TMPH-00524

Species: Enterobacteria phage T4

Expression System: E. coli

DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant

TMPH-00360

Species: Cenarchaeum symbiosum

Expression System: E. coli

DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His)

TMPH-03487

Species: Serratia marcescens

Expression System: E. coli

DNA-binding protein HU-alpha Protein, E. coli O157:H7, Recombinant (His & SUMO)

TMPH-00668

Species: E. coli

Expression System: E. coli

DNA-binding protein H-NS Protein, E. coli, Recombinant (His)

TMPH-00616

Species: E. coli

Expression System: E. coli

OGG1 Protein, Human, Recombinant

TMPJ-00457

Species: Human

Expression System: E. coli

Human adenovirus C serotype 5 DNA-binding protein (His)

TMPH-00898

Species: HAdV-5

Expression System: Baculovirus

Human adenovirus C serotype 2 DNA-binding protein (His)

TMPH-00896

Species: HAdV-2

Expression System: E. coli

Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO)

TMPH-03193

Species: Pyrococcus furiosus

Expression System: E. coli

Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)

TMPH-00039

Species: Agrobacterium fabrum

Expression System: E. coli

MGMT Protein, Human, Recombinant (His)

TMPJ-00872

Species: Human

Expression System: E. coli

DFF45 Protein, Human, Recombinant (His)

TMPJ-00483

Species: Human

Expression System: E. coli

PDRG1 Protein, Human, Recombinant (His)

TMPY-03601

Species: Human

Expression System: E. coli

GADD45A Protein, Human, Recombinant (His & GST)

TMPY-02150

Species: Human

Expression System: Baculovirus-Insect Cells

GADD45A Protein, Human, Recombinant (His)

TMPJ-00907

Species: Human

Expression System: E. coli

BLM Protein, Mouse, Recombinant (His & Myc)

TMPH-02550

Species: Mouse

Expression System: E. coli

GADD45G Protein, Human, Recombinant (His)

TMPJ-00711

Species: Human

Expression System: E. coli

GADD45G Protein, Human, Recombinant

TMPY-03655

Species: Human

Expression System: E. coli

BLM Protein, Human, Recombinant (His)

TMPH-01010

Species: Human

Expression System: E. coli

DsDNA-binding protein A Protein, Enterobacteria phage T4, Recombinant (His & Myc)

TMPH-00525

Species: Enterobacteria phage T4

Expression System: E. coli

AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)

TMPH-00359

Species: Caulobacter vibrioides

Expression System: E. coli

AlkB Protein, E. coli, Recombinant (His & Myc & SUMO)

TMPH-00577

Species: E. coli

Expression System: E. coli

Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His)

TMPH-01450

Species: HHV-6A

Expression System: Yeast

AICDA Protein, Mouse, Recombinant (His & Myc)

TMPH-02908

Species: Mouse

Expression System: E. coli

APOBEC3A Protein, Human, Recombinant (His & SUMO)

TMPH-01235

Species: Human

Expression System: E. coli

UNG Protein, Human, Recombinant (GST)

TMPY-02000

Species: Human

Expression System: E. coli

TDT Protein, Human, Recombinant (His)

TMPJ-00765

Species: Human

Expression System: E. coli

DFFB Protein, Human, Recombinant (His)

TMPH-01236

Species: Human

Expression System: E. coli

Nucleobindin-2 Protein, Human, Recombinant

TMPJ-01061

Species: Human

Expression System: E. coli

HEMK2 Protein, Human, Recombinant (His)

TMPY-02420

Species: Human

Expression System: E. coli

ZBP1 Protein, Human, Recombinant (His)

TMPJ-01328

Species: Human

Expression System: E. coli

CHD1L Protein, Human, Recombinant (His & SUMO)

TMPH-01091

Species: Human

Expression System: E. coli

APOBEC3C Protein, Human, Recombinant (GST)

TMPH-01903

Species: Human

Expression System: E. coli

Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)

TMPH-02997

Species: Mycobacterium smegmatis

Expression System: E. coli

DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc)

TMPH-02993

Species: Mycobacterium paratuberculosis

Expression System: E. coli

Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)

TMPH-00794

Species: Helicobacter pylori

Expression System: E. coli

APE1/APEX1 Protein, Human, Recombinant (His)

TMPY-02433

Species: Human

Expression System: E. coli

GADD45B Protein, Human, Recombinant (His)

TMPJ-00700

Species: Human

Expression System: E. coli

ALKBH5 Protein, Human, Recombinant (His)

TMPH-01899

Species: Human

Expression System: E. coli

DTD1 Protein, Human, Recombinant (His)

TMPJ-01241

Species: Human

Expression System: Human Cells

--------- More ---------

Cat No.	Product Name
L3900	DNA Damage & Repair Compound Library	937 compounds
	A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
L3980	DNA Damage and Repair Compound Library Plus	667 compounds
	Well-chosen 667 compounds with unique structures targeting DNA damage & repair;
L3510	Methylation Compound Library	131 compounds
	131 methylation-related compounds that can be used for high-throughput and high-content screening.
L1200	Epigenetics Compound Library	960 compounds
	Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L5500	Toxic Compound Library	277 compounds
	A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS);
L1380	Transcription Factor-Targeted Compound Library	704 compounds
	Well-chosen 704 compounds with unique structures targeting transcription factor;
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L8100	Cell Cycle Compound Library	695 compounds
	A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
L8300	Chromatin Modification Compound Library	256 compounds
	A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L1510	Nuclear Receptor Compound Library	546 compounds
	A unique collection of 546 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L3500	Histone Modification Compound Library	480 compounds
	A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
L8600	Ubiquitination Compound Library	214 compounds
	A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening；
L5300	Mitochondria-Targeted Compound Library	830 compounds
	A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L2910	Antioxidant Compound Library	1330 compounds
	Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L6120	Flavonoid Natural Product Library	477 compounds
	A unique collection of 477 flavonoids can be used for high throughput and high content screening；