T35528 |
TD52
|
1798328-24-1
|
99.5%
|
|
TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 bindin...
|
T8199 |
(±)-α-Bisabolol
|
515-69-5
|
99.44%
|
|
(±)-α-Bisabolol (Bisabolol) isa sesquiterpenol extracted from essential oils of chamomile, candida and other plants. It isa natural antiseptic with soothing, ant...
|
T10964L |
DB1976 dihydrochloride
|
2369663-93-2
|
99.08%
|
|
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and...
|
T14378 |
AZD5582
|
1258392-53-8
|
98.83%
|
|
AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.
|
T11146 |
EC359
|
2012591-09-0
|
98.11%
|
|
EC359 is a potent and selective inhibitor of leukemia inhibitory factor receptor (LIFR), a potent inhibitor with anticancer activity, blocks LIF/LIFR interaction...
|
TN3910 |
Ecdysone
|
3604-87-3
|
100%
|
|
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
|
T1947 |
BS-181
|
1092443-52-1
|
|
|
BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.
|
T3340 |
SCR7
|
1533426-72-0
|
|
|
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
|
T3081L |
EPZ004777 hydrochloride
|
1380316-03-9
|
|
|
EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
|
T4114 |
Diffractaic Acid
|
436-32-8
|
|
|
Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.
|
T4134L |
OTS514
|
1338540-63-8
|
|
|
OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed th...
|
T6724 |
Voreloxin
|
175414-77-4
|
98%
|
|
Voreloxin (SNS-595) is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity. Phase 2.
|
TN1694 |
Gliotoxin
|
67-99-2
|
98%
|
|
Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signalin...
|
T77713 |
BTM-3566
|
2228857-70-1
|
98%
|
|
BTM-3566 activates the ISR through the mitochondrial protease OMA1.BTM-3566 induces apoptosis in cancer cells. BTM-3566 overactivates the mitochondrial ISR to st...
|
T77732 |
HFY-4A
|
2094810-82-7
|
98%
|
|
HFY-4A is a novel HDAC inhibitor.HFY-4A has antitumour activity and has shown antiproliferative activity in breast cancer cells.
|
T78054 |
JNJ-1013
|
2597343-08-1
|
98%
|
|
JNJ-1013 is a potent and selective IRAK1 degrader, demonstrating IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis a...
|
T78156 |
MC4033
|
28532-21-0
|
98%
|
|
MC4033 exhibits inhibitory concentration 50 (IC50) values of 39.4 µM in HCT116, 52.1 µM in H1299, 41 µM in A549, and 30.1 µM in U937 [1]. Additionally, treatment...
|
T78404 |
Pyridinium bisretinoid A2E TFA
|
1821308-73-9
|
98%
|
|
Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates au...
|
T78569 |
CPT2
|
1670277-66-3
|
98%
|
|
Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC). Overexpression...
|
T78586 |
Ac-IETD-CHO
|
191338-86-0
|
98%
|
|
Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure. ...
|