7b-acetoxytaxuspine c

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b] The EC50 value of pyrazine against TREM2 was ≤ 0.05 μM and the E.max value was > 250 μM.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombophlebitis, atherosclerosis, cerebral embolism, stroke and pulmonary embolism.

3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.

Neurokinin B acetate(86933-75-7 free base) is the acetate form of Neurokinin B, which belongs to the tachykinin family. Neurokinin binds to neurokinin receptor 1 (NK1R), nk2r and NK3R, and mediates its biological effects.

C-Myc Inhibitor 7, serving as both a c-Myc inhibitor and a multi-target protein degrader, effectively degrades proteins c-MYC, CK1α, GSPT1, and IKZF1/2/3 across various tumor cell types. It holds potential for research into diseases associated with high c-Myc expression, including cancer, cardiovascular and cerebrovascular conditions, and viral infections.

7beta-Acetoxytaxuspine C is a natural product from Taxus canadensis.

5,6,7,4'-tetrahydroxyisoflavone-6,7-di-O-beta-D-glucopyranoside is a natural product

(11aR)-5-(4,5,6,7-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine is a useful organic compound for research related to life sciences and the catalog number is T64513.

Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosides

2-Amino-4-chloro-5-iodo-N2-pivaloyl-7-[2-deoxy-3,5-di-O- (4-methylbenzoyl)-b-D-ribofuanosyl]-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deazapurine nucleoside; Halo-nucleoside.

Nucleoside Derivatives - 7-Deaza-purine nucleosides; 6-De-aminopurine nucleosides

1-(2-C-b-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a Pyridine nucleoside; 2'-C-Methyl nucleoside.

2'-b-C-Ethynyladenosine is a Nucleoside Derivative - 2'-Modified nucleoside.

2,9-Dihydroxy-7-methoxy-4-methylnaphtho[1,2-b]fura is a useful organic compound for research related to life sciences. The catalog number is T125732 and the CAS number is 1558053-97-6.

Nucleosides and Reagents - 4-Deoxypyrimidine nucleoside; 2’-C-Methyl nucleoside

1-b-D-(3-Methoxy naphthalen-2-yl)-2’-deoxyriboside; 1,4-Anhydro-2-deoxy-1-C-(3-methoxy)-naphthalenyl)-D-erythro-pentitol is a useful organic compound for research related to life sciences. The catalog number is TNU1641 and the CAS number is 1117893-19-2.

2-Amino-4-chloro-N2-pivaloyl-7-[2-deoxy-3,5-di-O-(4- methylbenzoyl)-b-D-ribofuanosyl]-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deazapurine nucleoside; Halo-nucleoside.

Compound 11n (hMAO-B-IN-7) is a potent inhibitor of human monoamine oxidase-B (hMAO-B) that can cross the blood-brain barrier (BBB). It demonstrates an IC 50 value of 0.79±0.05 μM and is useful in research related to Alzheimer's disease (AD) and Parkinson's disease (PD) [1].

(11AS)-5-(4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine is a useful organic compound for research related to life sciences and the catalog number is T64639.

7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine is a building block.1It has been used in the synthesis of PI3K inhibitors. 1.Scott, W.J., Hentemann, M.F., Rowley, R.B., et al.Discovery and SAR of novel 2,3-dihydroimidazo[1,2-c]quinazoline PI3K inhibitors: Identification of copanlisib (BAY 80-6946)ChemMedChem.11(14)1517-1530(2016)

7-Xylosyltaxol B is a natural product from Taxus wallichiana var.mairei.

Nucleoside Derivatives - 7-Deaza-purine nucleoside

6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64405 and the CAS number is 1006-21-9.

Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66226 and the CAS number is 536759-91-8.

1-(2,3,5-Tribenzoyl-2-C-b-methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a Pyridine nucleoside; 2'-C-Methyl nucleoside.

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine is a useful organic compound for research related to life sciences and the catalog number is TNU0394.

Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half-maximal inhibitory concentrations (IC50s) of 6.7 nM and 5.2 nM, respectively [1].

4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a nucleoside derivative, specifically a 7-deaza-purine nucleoside with 2'-modifications. It is also categorized as a halo-nucleoside and serves as both a scaffold and template.

Nucleoside Derivatives - 7-Deazapurine nucleosides; Halo-nucleosides; Scaffolds and Templates

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1021.

7-O-Acetylbonducellpin C may exhibit significant inhibition of nitric oxide production of RAW264.7 macrophages stimulated by lipopolysaccharide (LPS).

Nucleoside Derivatives - 2’-Modified nucleosides, 7-Deaza-purine nucleosides, Halo-nucleosides

4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template.

4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1024.

Thieno[3,2-b]pyridin-7-ol has a wide range of applications in life science related research.

7-Xylosyl-10-deacetyltaxol C is a natural product from Taxus wallichiana Zucc.

7-Xylosyl-10-deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative from the Northeastern red bean tree (Picea abies) in the Sequoia family, with antitumor activity, and can be used for the synthesis of paclitaxel.

4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - Halo-nucleoside, 7-Deaza-purine nucleoside.

4-Chloro-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]-pyrimidine is a Nucleoside Derivative - Halo-nucleoside, 7-Deaza-purine nucleoside.

4-Amino-1-(2-b-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside.

2’-C-Methyl nucleoside; 2/6/8-Modified purine nucleoside

Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; N-Methylated alkylated nucleosides

2'-b-C-Methyl-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; 2'-Modified nucleoside.

9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-6-chloropurine is a useful organic compound for research related to life sciences and the catalog number is TNU0992.

2',3',5'-Tri-O-benzoyl-2'-b-C-methyl-6-azauridine is a nucleoside derivative, specifically a 2'-modified nucleoside of 6-aza-uridine.

B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor with an IC50 of 110.23 nM. It exhibits antitumor activity against colon carcinoma cells (HCT-116), mammary gland cells (MCF-7), hepatocellular carcinoma cells (HEPG-2), human cervical carcinoma cells (Hela), and human prostate cancer cells (PC-3), with IC50 values of 7.50, 9.87, 10.57, 11.63, and 12.83 μM, respectively [1].

Neurokinin B (NKB) belongs in the family of tachykinin peptides. Neurokinin B is implicated in a variety of human functions and pathways such as the secretion of gonadotropin-releasing hormone.

Neurokinin B TFA, a member of the tachykinin family, binds to a series of GPCRs, including neurokinin receptors 1 (NK1R), NK2R, and NK3R, to modulate their biological effects.