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8alpha-methacryloyloxybalchanin

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Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His)
TMPY-02160
Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 196 kDa and the accession number is P53708&P05556-1.
  • $498
7-10 days
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Integrin alpha V beta 8 Protein, Human, Recombinant (His)
TMPY-05717
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This mechanism differs from that of alpha V beta 6; the other alpha V integrin which can activate TGF-beta from latency through non-proteolytic mechanisms.
  • $517
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