1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor.

2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv showed high local anti-inflammatory potency and high lung selectivity when tested on Sprague Dawley rats.

3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one is a compound that has been extensively investigated for the treatment of a variety of disorders including tumors, Alzheimer's and Parkinson's diseases, anti-inflammatory drugs, and analgesic agents.

1H-benzo[d][1,2,3]triazol-1-yl 8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylate is a useful organic compound for research related to life sciences and the catalog number is T72065.

(Z)-2-fluoro-1,3-bis(4-methoxyphenyl)prop-2-en-1-one is a screening compound and can be used in new drug development related research.

Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3', 5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.

1,3-Butanediol, 1-(m-chlorophenyl)-4,4,4-trifluoro-3-trifluoromethyl- is a bioactive chemical.

5-Fluoro-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a useful organic compound for research related to life sciences and the catalog number is T64799.

2-(5-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium is a useful organic compound for research related to life sciences and the catalog number is T64625.

Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][[5-[(dimethylamino)sulfonyl]-2-(1-methylethoxy-O)phenyl]methylene-C]ruthenium(II) is a useful organic compound for research related to life sciences and the catalog number is T66135.

2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene is a natural product from Laggera pterodonta

1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione is a useful organic compound for research related to life sciences. The catalog number is T67692 and the CAS number is 764667-65-4.

4,4,4-Trifluoro-1-(p-tolyl)butane-1,3-dione is a useful organic compound for research related to life sciences. The catalog number is T66163 and the CAS number is 720-94-5.

1-[3-carboxypropyl]-3,7-dimethylxanthine-d6 is a deuterated compound of 1-[3-carboxypropyl]-3,7-dimethylxanthine.

4,4'-(Triaz-1-ene-1,3-diyl)dibenzimidamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64402 and the CAS number is 2331268-15-4.

4-(But-3-yn-1-ylamino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a useful organic compound for research related to life sciences and the catalog number is T64792.

4,4,4-Trifluoro-1-(m-tolyl)butane-1,3-dione is a useful organic compound for research related to life sciences. The catalog number is T66381 and the CAS number is 53764-99-1.

3-(6-Chloro-1-oxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)piperidine-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T64655.

Drugs and Inhibitors; toll-like receptor (TLR) agonist

1-(5-hydroxyhexyl)-3,7-dimethylxanthine-d6 is a deuterated compound of 1-(5-hydroxyhexyl)-3,7-dimethylxanthine.

2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65769 and the CAS number is 151257-01-1.

Ethyl 6,7-difluoro-1-methyl-4-oxo-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65447 and the CAS number is 113046-72-3.

1,3-Dihydro-1-(piperidin-4-yl)(2H)indol-2-one is a useful organic compound for research related to life sciences. The catalog number is T66455 and the CAS number is 16223-25-9.

3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine is a useful organic compound for research related to life sciences and the catalog number is TNU1667.

5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione is a useful organic compound for research related to life sciences. The catalog number is T64892 and the CAS number is 764667-64-3.

(1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67324 and the CAS number is 900160-98-7.

4-Fluoro-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a useful organic compound for research related to life sciences and the catalog number is T64616.

(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65762 and the CAS number is 147126-75-8.

4-Amino-1-[3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one is a Nucleoside Derivative - Protected nucleoside with NH2/OH group.

2-(2,6-Dioxopiperidin-3-yl)-4-(prop-2-yn-1-ylamino)isoindoline-1,3-dione is a useful organic compound for research related to life sciences and the catalog number is T64736.

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione is a useful organic compound for research related to life sciences and the catalog number is T64732.

Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Physiologically, this agent relaxes the bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates the cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm.

Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine. It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist. In vivo, paraxanthine increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agonist CPA or the adenosine A2 receptor agonist CGS 21680 in rats not habituated to caffeine. It also promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety.

Theophylline (1,3-Dimethylxanthine) sodium glycinate is a potent inhibitor of phosphodiesterase (PDE) that inhibits PDE3 activity to relax airway smooth muscle. Theophylline sodium glycinate can be used for the research of asthma and chronic obstructive pulmonary disease (COPD). Theophylline sodium glycinate is also an adenosine receptor antagonist and histone deacetylase (HDAC) activator. Theophylline sodium glycinate has anti-inflammatory activity by increasing IL-10 and inhibiting NF-κB nucleus import. Theophylline sodium glycinate induces apoptosis [1] [2] [3] [4] [5].

1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.