6 chloropurine riboside

6-Chloropurine riboside (6-CPR) is a purine nucleoside analog that has been found to have a wide range of biological activities. It inhibits the growth of tumor cells and induces apoptosis. It has also been shown to have anti-inflammatory, antiviral and antifungal properties. It has also been found to be neuroprotective and has been used in the treatment of neurological disorders.

6-Chloropurine riboside-5'-triphosphate serves as both an inhibitor and an activator in biochemical processes. It inhibits the RNA triphosphatase mRNA-capping enzyme subunit β (Cet1; IC50 = 2 µM for the GTPase activity of the S. cerevisiae enzyme), proving its efficacy against the enzyme responsible for the capping of mRNA molecules. Additionally, it acts as a phosphorylated derivative of 6-chloropurine riboside. This compound also activates the E. coli enzyme aspartate carbamoyltransferase (EC50 = 0.76 mM), demonstrating its versatility in modulating enzyme activities. It is instrumental in the synthesis of cytokinins with anticancer properties and a photoclickable form of ATP, highlighting its applications in biochemical synthesis and potential therapeutic uses.

2-Amino-6-chloropurine-9-beta-D-(2'-deoxy)riboside is a 2'-deoxy nucleoside and halo-nucleoside.

2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a Halo-nucleoside; 2'-O-Methyl nucleoside.

2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-3',5'-di-(O-p-toluoyl))riboside is a 2'-deoxy nucleoside and halo-nucleoside.

Nucleoside Derivatives - 2’-Modified nucleosides, Halo-nucleosides; Scaffolds and Templates

6-Chloropurine (6-Chloro-9H-purine) is a building block in chemical synthesis,with Antitumor activities.

2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a fluoro-modified nucleoside, halo-nucleoside, and arabino-nucleoside.

6-Chloro-7-deazapurine-β-D-riboside shows antifungal activity.

Nucleoside Derivatives - Fluoro-modified nucleosides; 6-Modified purine nucleosides, 3’-Modified nucleosides

9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a Nucleoside Derivative used as a 3'-Deoxy nucleoside, Halo-nucleoside, scaffold, and template.

2-Amino-6-chloropurine is a precursor in the synthesis of nucleoside analogs with antiviral activity against Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6).1 1.Qiu, Y.-L., Ksebati, M.B., Ptak, R.G., et al.(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activityJ. Med. Chem.41(1)10-23(1998)

9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-6-chloropurine is a useful organic compound for research related to life sciences and the catalog number is TNU0992.

(S)-9-(2,3-Dihydroxypropyl)-2-amino-6-chloropurine is a Nucleoside Derivative - Acyclic nucleoside.

3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside is a nucleoside derivative classified under other modified nucleosides.

Nucleoside - 2’-deoxy nucleoside; halo nucleoside

Nucleoside Derivatives –6-Modified purine nucleosides, 3’-modified nucleosides

6-Chloropurine -9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside is a Fluoro-modified nucleoside; Halo-nucleoside; Arabino-nucleoside.

2-Chloro-6-(furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside is a nucleoside derivative that is a fluoro-modified nucleoside, 6-modified purine nucleoside, halo-nucleoside, and 3'-modified nucleoside; it serves as a scaffold and template.

2-Amino-6-O-methyl-2’-O-methyl purine riboside, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis, among others [1].

9-(2,3-Di-O-acetyl-6-O-benzoyl-5-deoxy-D-ribo-exofuranoyl)-6-chloropurine is an organic compound useful for life sciences research (catalog number: TNU1673).

2-Amino-6-O-methyl-2'-O-methyl purine riboside is a Nucleoside Derivative - 6-Modified purine nucleoside, 2'-Modified nucleoside.

9-(2,5-Di-O-benzoyl-2-C-beta-ethynyl-beta-D-ribofuranosyl)-6-chloropurine is a useful organic compound for research related to life sciences and the catalog number is TNU1616.

Nucleoside Derivatives - Halo-nucleosides, 2’-Modified nucleosides; Scaffolds and Templates

6-Chloroguanineriboside is a Halo nucleoside.

6-Methoxypurine-9-beta-D-(3-methoxy riboside), a purine nucleoside analog, exhibits extensive antitumor effects, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, among others [1].

9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine, a purine nucleoside analog, demonstrates broad antitumor activity, particularly against indolent lymphoid malignancies, through inhibition of DNA synthesis and induction of apoptosis. [1]

Nucleoside Derivatives - Azido-nucleoside; 6-Modified purine nucleoside; 3’-Modified nucleoside

Nucleoside Derivatives - Halo-nucleosides, 6-Modified purine nucleosides, 2’-Modified purine nucleosides

6-(Furan-2-yl)purine-beta-D-riboside is a Nucleoside Derivative - 6-Modified purine nucleoside.

Fluoro-modified nucleoside; Halo-nucleoside

2',3',5'-Tri-O-acetyl-6-chloroguanosine is a Halo-nucleoside.

6-Chloro-2-iodopurine-9-riboside is a Halo nucleoside.

Nucleosides - 3’-O-methyl nucleoside; halo-nucleoside

Nucleoside Derivatives - Fluoro-modified nucleoside; Halo-nucleoside

2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside is a Fluoro-modified nucleoside; Halo-nucleoside; Arabino-nucleoside.