6beta-hydroxy dexamethasone

6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilized for research in the fields of chemistry and life sciences.

2-Hydroxy-6-methoxybenzoic acid (6-Methoxysalicylic acid) may be employed as internal standard for the determination of acetylsalicylic acid (aspirin, ASA) and its major metabolite, salicylic acid (SA),and exhibits significant analgesic effects

4-Hydroxy-6-methylcoumarin (4-HMC) is a naturally occurring phenolic compound, a derivative of coumarin, found in a variety of plants, fungi, and bacteria. It has anti-inflammatory and anti-tumor activity.4-HMC is used as a flavoring agent, preservative and antioxidant in the food industry.

6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α with an IC50 value of 0.08 μM.

(+)-6-(2-Hydroxy-3-methoxy-3-methylbutyl is a structural isomer of Ent-toddalolactone, which belongs to the coumarin group.

3-Hydroxy-6-methoxyflavone can be used in combination with antibiotics to treat ESKAPE pathogen infections.

(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one ((5R)-trans-1,7-diphenyl-5-hydroxy-6-hept) possesses antioxidant activity.

6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.

1. 6'-O-beta-D-Glucosylgentiopicroside (6'-O-Glucosylgentiopicroside) may have antifungal activity.

6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.

6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, demonstrating efficacy in the rat hippocampus and dorsal raphe with half-maximal effective concentrations (EC50s) of 4 and 1 µM, respectively. Furthermore, 6-Hydroxy Buspirone acts as a potent antagonist against dopamine D2, D3, and D4 receptors with half-maximal inhibitory concentrations (IC50s) of 3.1, 4.9, and 0.85 µM, respectively, and inhibits the organic cation transporters 1 (OCT1), OCT2, and OCT3 in S2 proximal tubule cells expressing human transporters, showcasing a concentration-dependent mechanism.

1-(3',5'-dimethoxy)phenyl-2-[4''-O-β-D-glucopyranosyl (6→1)-O-α-L-rhamnopyranosyl]phenylethane showed cytotoxic activities to Hela and hep2 cell lines.

6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone is an alkenylphenol from Piper obliquum with antiinflammatory and antibacterial activities.

7-Hydroxy-beta-carboline-1-propionic acid is a useful organic compound for research related to life sciences and the catalog number is T125336.

Methyl 2-(6-acetyl-5-hydroxy-2,3-dihydrobenzofuran-2-yl)propenoate is a natural product from Vernonia cinerea.

4-Hydroxy-3-methoxyphenol 1-O-(6-O-syringoyl)glucoside is a useful organic compound for research related to life sciences and the catalog number is T124850.

6-Hydroxy-3,4-dihydroquinolin-2(1H)-one is a useful organic compound for research related to life sciences. The catalog number is T67507 and the CAS number is 54197-66-9.

5-Hydroxy-canthin-6-one is a natural product for research related to life sciences. The catalog number is TN3122 and the CAS number is 64118-73-6.

Benzyl 2-hydroxy-6-(β-glucosyloxy)benzoate is a natural product for research related to life sciences. The catalog number is TN5679 and the CAS number is 403857-21-6.

6-Hydroxy-5,7,3',4',5'-pentamethoxyflavone is a natural product for research related to life sciences. The catalog number is TN6355 and the CAS number is 29043-06-9.

2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuranosyl)-9H-purine is a nucleoside derivative, specifically a 3'-deoxy nucleoside and halo-nucleoside, serving as a scaffold and template.

6-Chloro-2-bromo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template.

9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a Nucleoside Derivative used as a 3'-Deoxy nucleoside, Halo-nucleoside, scaffold, and template.

Nucleoside Derivatives - Fluoro-modified nucleosides; 6-Modified purine nucleosides, 3’-Modified nucleosides

2-Amino-6-chloro-9-(3-deoxy-2-O-acetyl-5-O-benzoyl-beta-D-ribofuanosyl)-9H-purine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template.

2’-C-Methyl nucleoside; 2/6/8-modified nucleoside

2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a fluoro-modified nucleoside, halo-nucleoside, and arabino-nucleoside.

2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside.

6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one is a natural product for research related to life sciences. The catalog number is TN3141 and the CAS number is 949081-05-4.

N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1623 and the CAS number is 145594-00-9.

6-Hydroxy-TSU-68, a derivative and metabolite of TSU-68, reflects the compound's self-induced hydroxylation in human liver microsomes [1].

6-Hydroxy Etodolac, a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac, causes false positives in diazo diagnostic tests for urinary bilirubin.

(S)-5-hydroxy-6-methoxy Duloxetine, an active metabolite of the (S)-duloxetine, functions as a serotonin (5-HT) and norepinephrine reuptake inhibitor. Its formation occurs through the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6 via a 5- or 6-hydroxy duloxetine intermediate, followed by a catechol duloxetine intermediate. This compound effectively inhibits the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) across lipid membranes, with inhibition constants (Kis) of 266, 920, and 2,814 nM, respectively, for human transporters.

4-[4-[[6-O-[(2E)-3-(4-Hydroxyphenyl)-1-oxo-2-propen-1-yl]-2-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranosyl]oxy]phenyl]-2-butanone is a natural product for research related to life sciences. The catalog number is TN5281 and the CAS number is 105274-16-6.

Benzyl 2-hydroxy-6-methoxybenzoate exhibits potent antifungal activity, demonstrating an IC 50 of 25–26 μg/mL against fungal strains.

6-Methoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine is a purine nucleoside analog with broad antitumor activity targeting indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis [1].

Methyl 2-hydroxy-6-methylbenzoate is a useful organic compound for research related to life sciences. The catalog number is T66105 and the CAS number is 33528-09-5.

4-Hydroxy-1-methoxycarbonyl-beta-carboline is a useful organic compound for research related to life sciences and the catalog number is T124278.

5-Hydroxy-1,7-diphenylhept-6-en-3-one is a natural product for research related to life sciences. The catalog number is TN6357 and the CAS number is 155239-30-8.

6-Hydroxy-3,3',4',5,7,8-hexamethoxyflavone is a useful organic compound for research related to life sciences. The catalog number is T125628 and the CAS number is 167416-97-9.

2-Amino-6-chloro-9-(3’-O-methyl-beta-D-ribofuranosyl)-9H-purine is a useful organic compound for research in the life sciences [catalog number: TNU1595].

Fluoro-modified nucleoside; Halo-nucleoside; 2/6/8-Modified purine nucleoside; Arabino-nucleoside;

2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside is a Fluoro-modified nucleoside; Halo-nucleoside; Arabino-nucleoside.

13-Hydroxy-7,14-labdadiene-6-one is a useful organic compound for research related to life sciences and the catalog number is T130143.

Fluoro-modified nucleoside; Iso-guanosine derivative; Arabino-nucleoside

Intermediates and Building Blocks - Nucleoside base, Electrophile; Heterocyclic Compounds - Pyridine; Scaffolds and Templates

Nucleosides - 3’-O-methyl nucleoside; halo-nucleoside

Fluoro-modified nucleoside; Halo-nucleoside