Search Result

Search Results for "apoptosis"

Targets

Libraries

Apoptosis Compound Library Microtubule-Targeted Compound Library Mitochondria-Targeted Compound Library Polyphenolic Natural Product Library Autophagy Compound Library MAPK Inhibitor Library FDA-Approved Kinase Inhibitor Library Ferroptosis Compound Library Ubiquitination Compound Library TGF-beta/Smad Compound Library Cell Cycle Compound Library Osteogenesis Compound Library Cancer Cell Differentiation Compound Library Endoplasmic Reticulum Stress Compound Library Exosome Compound Library NF-κB Signaling Compound Library Traditional Chinese Medicine Monomer Library Chinese Pharmacopoeia Natural Product Library HIF-1 Signaling Pathway Compound Library Cuproptosis Compound Library

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Compounds

Cat No.	Product Name
T5793	Britannin		Apoptosis , Autophagy , AMPK
	Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pat...		Apoptosis , Autophagy , AMPK
T10580	BOC-D-FMK		Caspase , Apoptosis
	Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by ...		Caspase , Apoptosis
TN3594	Cardanol (C15:1)		Others , Apoptosis
	Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells.		Others , Apoptosis
T8678	Naphthazarin	5,8-Dihydroxy-1,4-naphthoquinone , DHNQ	Apoptosis
	Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptos...		Apoptosis
T33296	Merodantoin		Apoptosis
	Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin tar...		Apoptosis
TN1684	Ginsenoside F5		Apoptosis
	Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the a...		Apoptosis
T13009	STAT3-IN-1		Apoptosis , STAT
	STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and ...		Apoptosis , STAT
T35329L	EAD1 HCl	EAD1 HCL(1644388-26-0 Free base)	Apoptosis , Autophagy
	EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL a...		Apoptosis , Autophagy
T14298	Rimiducid		Apoptosis , Others , Fatty Acid Synthase
	Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wi...		Apoptosis , Others , Fatty Acid Synthase
T27093	CT-1	CT 1	p53
	CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.		p53
T27579	ICL-CCIC-0019	ICL CCIC 0019	AChR
	ICL-CCIC-0019 is an inhibitor of choline kinase alpha (ChoKα). ICL-CCIC-0019 induces G1 arrest, endoplasmic reticulum st...		AChR
T41248	Thiocolchicine		Microtubule Associated
	Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchi...		Microtubule Associated
TQ0138	K145 hydrochloride		Apoptosis , S1P Receptor
	K145 is a specific inhibitor of SphK2 (IC50: 4.30 μM), while no inhibition of SphK1 at concentrations up to 10 μM.		Apoptosis , S1P Receptor
T40130	Nur77 modulator 1		Others
	Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-c...		Others
T9712	PF07104091	PF-07104091	CDK
	PF-07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation.		CDK
T60217	TAS1553		Others
	TAS1553 is a potent, orally active protein–protein interaction (PPI) inhibitor with an IC 50 values of 0.0396 μM. TAS155...		Others
T11820	LAT1-IN-1	BCH	Apoptosis , Others
	LAT1-IN-1 (BCH) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppre...		Apoptosis , Others
T11052L	Disitertide acetate	Disitertide acetate(272105-42-7 Free base) , P144 acetate	TGF-beta/Smad
	Disitertide acetate is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block th...		TGF-beta/Smad
T5715	(E)-Flavokawain A	FLAVOKAVAIN A(P)	P450 , Apoptosis
	Flavokavin A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protei...		P450 , Apoptosis
T39823L	Apelin-12 acetate		Apelin receptor , p38 MAPK , JNK
	Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 ...		Apelin receptor , p38 MAPK , JNK