4' hydroxy flurbiprofen

4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.

(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine. Sinomenine is an alkaloid derived from the Chinese herb Sinomenium acutum (Thunb.) Rehd. et Wils. (9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one exhibits anti-inflammation effects.

4-Hydroxy-6-methylcoumarin (4-HMC) is a naturally occurring phenolic compound, a derivative of coumarin, found in a variety of plants, fungi, and bacteria. It has anti-inflammatory and anti-tumor activity.4-HMC is used as a flavoring agent, preservative and antioxidant in the food industry.

3-Hydroxy-1-(4-hydroxyphenyl)propan-1-one (3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone) is a natural product derived from plant source.

9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.

4-Hydroxy-5-methyl-3-furanone (4-Hydroxy-5-methylfuran-3(2H)-one) is a natural product isolated from Eurycotis floridana.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

2-(4-methoxyphenyl)-2-oxoethyl 2-hydroxy-5-methylbenzoate is a pro-neurotropic drug used to enhance cognitive function by increasing the synthesis and release of acetylcholine in the brain as well as by inhibiting the breakdown of acetylcholine by acetylcholinesterase.

4-Hydroxy-3-Nitrobenzyl Alcohol (4-(Hydroxymethyl)-2-nitrophenol) is a marine derived natural products found in Phidolopora pacifica.

4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.

Pyrazinecarboxamide, 3,4-dihydro-4-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-oxo- is a useful organic compound for research related to life sciences. The catalog number is TNU0422L and the CAS number is 356783-01-2.This compound is unstable in powder form and other related salt forms are recommended.

2-((1R,2R)-2-Formyl-1,3,3-trimethylcyclohexyl)-4-hydroxy-5-isopropylbenzaldehyde is a naturally occurring compound [1].

(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone featuring a complex bicyclic structure [1].

3-Hydroxy-4',5-dimethoxystilbene is a natural product of Dracaena, Liliaceae. The catalog number is TN2941 and the CAS number is 58436-29-6. 3-Hydroxy-4',5-dimethoxystilbene can be used as a reference standard.

6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone is an alkenylphenol from Piper obliquum with antiinflammatory and antibacterial activities.

7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) is a natural product for research related to life sciences. The catalog number is TN3217 and the CAS number is 79559-60-7.

2-(4-Hydroxy-3-methoxyphenyl)-7-methoxy-5-benzofuranpropanol is a natural product for research related to life sciences. The catalog number is TN5407 and the CAS number is 144735-57-9.

4-Hydroxy-1,10-secocadin-5-ene-1,10-dione is a natural product of Casearia, Flacourtiaceae. The catalog number is TN3031 and the CAS number is 226904-40-1. 4-Hydroxy-1,10-secocadin-5-ene-1,10-dione can be used as a reference standard.

1-Hydroxy-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)propan-2-one is a natural product for research related to life sciences. The catalog number is TN2532 and the CAS number is 117614-84-3.

8-Hydroxy-4-cadinen-3-one shows significant inhibitory activity against A.thaliana seedling root growth.

6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one is a natural product for research related to life sciences. The catalog number is TN3141 and the CAS number is 949081-05-4.

(4′-Hydroxy)phenoxybenzoic acid is a pyrethroid insecticide metabolite.1,2 1.Akhtar, M.H., Mahadevan, S., and Russell, F.Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparationsJ. Environ. Sci. Health B.28(5)527-543(1993) 2.Maloney, S.E., Maule, A., and Smith, A.R.Microbial transformation of the pyrethroid insecticides: Permethrin, deltamethrin, fastac, fenvalerate, and fluvalinateAppl. Environ. Microbiol.54(11)2874-2876(1988)

TLR7/8 agonist 4 hydroxy-PEG6-acid, a Drug-Linker Conjugate for ADCs, comprises the TLR7/8 agonist 4 and a hydroxy-PEG6-acid linker, suitable for the synthesis of antibody-drug conjugates (ADCs) [1].

8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone may have antifungal activity against phytopathogenic and human pathogenic fungi.

(2S)-4'-Hydroxy-7-methoxyflavan, a flavan, demonstrated significant cytotoxic effects on human leukemic Molt 4 cells [1].

4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermediate. It is released into the blood and cerebrospinal fluid and has been used as a biochemical index of recent sympathetic nervous system activity.

5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone (DHPA) is a pancreatic lipase inhibitor, it shows antihyperlipidemic activity.

2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is a chemical compound and an isomer of Vanillin. 2-Hydroxy-4-methoxybenzaldehyde(4-Methoxysalicylaldehyde) could be used to synthesis Urolithin M7. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond.

5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate is a natural product for research related to life sciences. The catalog number is TN3115 and the CAS number is 1269839-24-8.

7-Hydroxy-3-(4'-hydroxybenzylidene)-chroman-4-one may have anti-inflammatory activity.

Peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat. About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates. The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form γ-lactols and γ-lactones, respectively, producing at least 4 or 5 end urinary metabolites of 4-HNE in vivo.

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood.

4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity found in Policresulen, which serves as a powerful NS2B/NS3 protease inhibitor, exhibiting an IC50 of 0.48 μg/mL. Additionally, Policresulen is an effective suppressor of DENV2 virus replication within BHK-21 cells, demonstrating an IC50 value of 4.99 μg/mL. It functions as a competitive inhibitor of the protease and marginally influences the enzyme's stability [1].

4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is selective for OAT3 over OAT1 (Ki= >200 μM).2 1.Yamato, C., Takahashi, T., Fujita, T., et al.Studies on metabolism of trazodone, II. Metabolic fate after intravenous administration and effects on liver microsomal drug-metabolizing enzymes in ratsXenobiotica4(12)765-777(1974) 2.Zou, L., Matsson, P., Stecula, A., et al.Drug metabolites potently inhibit renal organic anion transporters, OAT1 and OAT3J. Pharm. Sci.110(1)347-353(2021)

7-methoxy-8-hydroxy-4-methylcoumarin is a compound isolated from Citrus aurantium.

3-Hydroxy-4-methoxyacetophenone (Acetoisovanillone) is an active P. spinosa extract. It possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon.

2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. 2'-Hydroxy-4'-methylacetophenone has acaricidal activity, it could be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl) oxy] acetophenone.

cis-L-Hydroxyproline inhibits the synthesis and extracellular deposition of collagen. The growth inhibition of pancreatic cancer cells induced by the Hyp isomer could be due to endoplasmatic reticulum stress.

4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.

4-hydroxy Atorvastatin is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.

4'-Hydroxy-2,4-dimethoxychalcone is a naturally occurring chalcone derivative from the herbal resin of the red geranium Dragon's Blood.4'-Hydroxy-2,4-dimethoxychalcone possesses a wide range of biological activities including anti-malarial, anti-bacterial, anti-fungal, and anti-protozoa activity.

8-Hydroxy-3,5,7,3',4',5'-hexamethoxyflavone is a natural product for research related to life sciences. The catalog number is TN3279 and the CAS number is 202846-95-5.

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction[2].

rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide .1,2It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9.1rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50values of 0.95 and 100 nM, respectively.2 1.Zharikova, O.L., Fokina, V.M., Nanovskaya, T.N., et al.Identification of the major human hepatic and placental enzymes responsible for the biotransformation of glyburideBiochem. Pharmacol.78(12)1483-1490(2009) 2.Hill, R.A., Rudra, S., Peng, B., et al.Hydroxyl-substituted sulfonylureas as potent inhibitors of specific [3H]glyburide binding to rat brain synaptosomesBioorg. Med. Chem.11(9)2099-2113(2003)

3-(4-Hydroxy-3,5-dimethoxyphenyl)-1,2-propanediol is a natural product for research related to life sciences. The catalog number is TN2885 and the CAS number is 22805-15-8.

4-Hydroxy-4-(methoxycarbonylmethyl)cyclohexanone is a natural product for research related to life sciences. The catalog number is TN3037 and the CAS number is 81053-14-7.

It is a metabolite of tamoxifen and an estrogen receptor modulator.

trans-4-Hydroxy-2-nonenoic acid (compound 4), a natural product, can be isolated from the genus Pottsia [1].

Hydroxy-2,6,10-trimethyl-2,6,11-dodeca-4-one is a naturally occurring compound present in the Solanaceae family [1].

5-Hydroxy-7-methoxy-3-(4-hydroxybenzylidene)chroman-4-one is a natural product for research related to life sciences. The catalog number is TN3121 and the CAS number is 259653-54-8.