4-trifluoromethyl

N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine is a biologically active compound belonging to the piperazine group. It is an important synthetic intermediate used in the preparation of a wide range of drugs, agrochemicals and other chemicals. It is considered an inhibitor of certain enzymes involved in drug metabolism, such as cytochrome P450 enzymes, and has also been shown to have anti-inflammatory and antitumor effects.

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.

4-Chloro-3-(trifluoromethyl)phenyl isocyanate is a biochemical reagent that can be produced by a series of reactions between o-chlorobenzotrifluoride and acetic anhydride.

2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE is a monoamine neurotransmitter. It has been studied for its potential to modulate the activity of various neurotransmitters, including serotonin, dopamine, and norepinephrine. Its potential as a 5-HT2A receptor agonist has also been studied.

2,3,5-TRIFLUORO-4-(TRIFLUOROMETHYL)PYRIDINE is a useful organic compound for research related to life sciences. The catalog number is T7272 and the CAS number is 675602-93-4.

4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid is used as a pharmaceutical intermediate.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

1-(Piperidin-4-yl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one is a useful organic compound for research related to life sciences and the catalog number is T66378.

4-(Trifluoromethyl)-D-phenylalanine is a useful organic compound for research related to life sciences. The catalog number is T67196 and the CAS number is 114872-99-0.

Methyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate is a useful organic compound for research related to life sciences and the catalog number is T64807.

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6'-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione is a useful organic compound for research related to life sciences. The catalog number is T67236 and the CAS number is 1352957-59-5.

(R)-tert-Butyl (4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate is a useful organic compound for research related to life sciences and the catalog number is T65597.

Ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate is a useful organic compound for research related to life sciences and the catalog number is T64863.

2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide is a useful organic compound for research related to life sciences. The catalog number is T67382 and the CAS number is 24522-30-3.

Benzenesulfonamide, N-(4-chloro-3-(trifluoromethyl)phenyl)-4-fluoro- is a bioactive chemical.

3-((3,5-Bis(trifluoromethyl)phenyl)amino)-4-(((1R)-(6-methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione is a useful organic compound for research related to life sciences. The catalog number is T67231 and the CAS number is 1256245-79-0.

N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T66252 and the CAS number is 90357-51-0.

2-(2-(4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethoxy)ethanol dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67203 and the CAS number is 1535-17-7.

4-(Trifluoromethyl)benzeneboronic acid is used to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.

N-Boc-4-(trifluoromethyl)-L-phenylalanine is a useful organic compound for research related to life sciences. The catalog number is T65536 and the CAS number is 114873-07-3.

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine is a useful organic compound for research related to life sciences. The catalog number is T66986 and the CAS number is 767340-03-4.

Benzenesulfonamide, N-(2-chloro-5-(trifluoromethyl)phenyl)-4-fluoro- is a bioactive chemical.

N-(4-Cyano-3-(trifluoromethyl)phenyl)methacrylamide is a useful organic compound for research related to life sciences. The catalog number is T65344 and the CAS number is 90357-53-2.

tert-Butyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate is a useful organic compound for research related to life sciences and the catalog number is T64607.

2'-Chloro-N6-(4-trifluoromethyl)benzyl adenosine is a Nucleoside Derivative - Halo-nucleoside;2-Modified purine nucleoside; 6-Modified purine nucleoside;.

1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione is a useful organic compound for research related to life sciences. The catalog number is T67692 and the CAS number is 764667-65-4.

1,3-Bis(4-chloro-3-(trifluoromethyl)phenyl)urea is a useful organic compound for research related to life sciences. The catalog number is T64474 and the CAS number is 370-50-3.

it is also called 5-Amino-2-nitrobenzotrifluoride.

N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)thio)-2-hydroxy-2-methylpropanamide is a useful organic compound for research related to life sciences. The catalog number is T65616 and the CAS number is 90356-78-8.

N-Methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide is a useful organic compound for research related to life sciences and the catalog number is T67100.

4-(Trifluoromethyl)phenol is a useful organic compound for research related to life sciences. The catalog number is T66972 and the CAS number is 402-45-9.

4-(Trifluoromethyl)-L-phenylalanine is a useful organic compound for research related to life sciences and the catalog number is T65695.

trans-4-(Trifluoromethyl)cinnamic acid is a photosensitizing compound. It is used as a reagent in the synthesis of various compounds, such as heterocyclic compounds and pharmaceuticals. It has also been used as a catalyst for organic reactions such as the Heck reaction and the Suzuki-Miyaura reaction. It is also used as a fluorescent probe in biological studies to detect and monitor various biomolecules.

4-(Trifluoromethyl)cinnamic acid is a useful organic compound for research related to life sciences and the catalog number is T67405.

N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((2-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide is a useful organic compound for research related to life sciences. The catalog number is T66984 and the CAS number is 1159977-36-2.

7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a galanin receptor 2 (GalR2) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 inhibitor with the activity value of 21 uM.

4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester is a useful organic compound for research related to life sciences. The catalog number is T67028 and the CAS number is 87736-89-8.

4-Bromo-3-(trifluoromethyl)aniline is a useful organic compound for research related to life sciences. The catalog number is T64898 and the CAS number is 393-36-2.

3-(4-(Trifluoromethyl)phenyl)propan-1-ol is a useful organic compound for research related to life sciences. The catalog number is T66873 and the CAS number is 180635-74-9.

S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.

NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention and treatment of cardiac hypertrophy.

A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist

ML267 (4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate) is a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth[1].

I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.

NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.

CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-α and IL-1β activated by R-848 in THP-1 cells.

TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor

Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.

Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy.