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Search Result

Search Results for " 5-fluorouracil "

Targets

Apoptosis Nucleoside Antimetabolite/Analog HIV Protease DNA/RNA Synthesis Endogenous Metabolite

30

Compounds

4

Natural Products

11

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T0984 5-Fluorouracil 5-FU,Fluorouracil,NSC 19893,5-Fluoracil Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , DNA/RNA Synthesis , Endogenous Metabolite
5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis. 5-Fluorouracil has antitumor activity and affects pyrimidine synthesis through inhibition of thymidylate synthase. 5-Fluorouracil causes apoptosis ...
T36895 5-Fluorouracil-13C,15N2 5-Fluorouracil-13C,15N2
5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking...
T36870 5,6-dihydro-5-Fluorouracil 5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione Others
5,6-dihydro-5-Fluorouracil (5-FUH2) is an inactive metabolite of 5-FU and can be used for the study of organismal metabolism.
T7614 Eniluracil GW776C85,5-Ethynyluracil Others
Eniluracil (GW776C85) is an orally activedihydropyrimidine dehydrogenase (DPD) inhibitor,increases the oral bioavailability of 5-FU to 100%, facilitating uniform absorption and predictable toxicity.
T10013 1-Acetyl-3-o-toluyl-5-fluorouracil A-​OT-​Fu Others
1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.
T0964 Floxuridine 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640 Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV
Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
T33762 Fosifloxuridine nafalbenamide NUC-3373,NUC3373,NUC 3373 DNA/RNA Synthesis
Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher c...
T1307 Carmofur HCFU Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
TNU1053 5-Fluorouracil-1-yl  acetic acid
5-Fluorouracil-1-yl  acetic acid is a PNA-related derivative.
TNU1481 1-(b-D-Xylofuranosyl)-5-fluorouracil
1-(b-D-Xylofuranosyl)-5-fluorouracil is a nucleoside derivative-xylo-nucleoside, fluoro-modified nucleoside, 5-modified pyrimidine nucleoside.
TNU1052 5-Fluorouracil-1-yl  acetic acid methyl ester
5-Fluorouracil-1-yl  acetic acid methyl ester is a PNA-related derivative.
T1349 5-Fluorouridine Others , DNA/RNA Synthesis
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...
T27259 Emitefur BOFA2,BOF A2,BOF-A2 Others
Emitefur (BOF-A 2) is an orally active and potent 5-fluorouracil derivative with anticancer and antitumor activity.Emitefur is used in advanced gastric cancer, breast cancer and metabolism-related diseases.
T1600 Doxifluridine Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by...
T1408 Capecitabine Xeloda,Capecitibine,Capiibine,RO 09-1978 Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie...
T9936 ZX-J-19J N-(2,3-Diphenyl-6-quinoxalinyl)octanamide Others
ZX-J-19J (N-(2,3-Diphenyl-6-quinoxalinyl)octanamide), an inhibitor of Cyclophilin J (CyPJ), demonstrates remarkable inhibition of tumor cell growth, comparable to cyclosporine A but much stronger than 5-fluorouracil.
T4374 Edoxudine Aedurid,EUDR,Epoxudine Antiviral , Antibacterial
Edoxudine (Epoxudine), an antiviral drug, is an analogue of thymidine and shows effectiveness against the herpes simplex virus. Edoxudine is used as a 5-fluorouracil (FU) modulator. Edoxudine may be used to enhance the t...
T21327 Uridine triacetate RG 2133 triacetate,PN-401,Tri-O-acetyluridine,PN401,RG 2133,RG-2133,PN 401,RG2133,RG2133 triacetate Others
Uridine triacetate (RG 2133 triacetate) (Tri-O-acetyl uridine), an orally active prodrug of uridine, is efficiently absorbed in the gut and swiftly deacetylated in the circulation to release free uridine. It is utilized ...
T28831 Sparfosate sodium CI882,CI-882,CI 882
Sparfosate is a 5-fluorouracil biomodulator.
T33686 Nitrocaphane AT 1258,AT-1258,AT1258
Nitrocaphane, in combination with 5-FU (fluorouracil), chemotherapy is considered as a protocol of choice in the treatment of malignant trophoblastic tumor.
T31837 FOLFIRI Regimen FOLFIRI
FOLFIRI Regimen is a chemotherapy regimen consisting of leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan used during the treatment of advanced-stage and metastatic colorectal cancer.
T40932 Benzylacyclouridine 5-Benzylacyclouridine,BAU
Benzylacyclouridine (BAU) is a powerful and selective inhibitor of uridine phosphorylase, the initial enzyme involved in uridine catabolism. Additionally, it can regulate the cytotoxic adverse effects of 5-fluorouracil (...
T72991 Bis-Pro-5FU
Bis-Pro-5FU, a precursor to 5-Fluorouracil (5-FU), enhances the oral bioavailability and safety profile of 5-FU chemotherapy treatments. 5-FU itself is an antineoplastic antimetabolite extensively utilized in the researc...
T74046 D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
D-Ribofuranose 1-dihydrogen phosphate dicyclohexanamine, commonly referred to as ribose 1-phosphate, serves as a precursor in the synthesis of 5-fluorouracil (FUra) via uridine phosphorylase [1].
T35439 (E)-5-(2-Bromovinyl)uracil
(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibl...
T63074 Ivaltinostat formic
Ivaltinostat (CG-200745) formic is an oral active panHDAC inhibitor with an isohydroxamic acid component that binds zinc at the bottom of the catalytic pocket. Ivaltinostat formic inhibited the deacetylation of histone H...
T36385 Ansatrienin A
Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis. In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 64 nM)...
T36650 Ansatrienin B
Ansatrienin B is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis., In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 21 nM...
T83881 4-(3,4-Difluorobenzo)curcumin CDF
4-(3,4-Difluorobenzo)curcumin (CDF) is a semisynthetic coumarin noted for its antiparasitic and anticancer properties. It effectively reduces the population of Vero cells infected by T. gondii promastigotes and amastigot...
T36424 DSPE-PEG(2000)-amine (sodium salt)
DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE . It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.1,2,3D...

Compounds

5-Fluorouracil
T0984
Synonym: 5-FU,Fluorouracil,NSC 19893,5-Fluoracil
Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, DNA/RNA Synthesis, Endogenous Metabolite
5-Fluorouracil-13C,15N2
T36895
Synonym: 5-Fluorouracil-13C,15N2
Target:
5,6-dihydro-5-Fluorouracil
T36870
Synonym: 5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione
Target: Others
Eniluracil
T7614
Synonym: GW776C85,5-Ethynyluracil
Target: Others
1-Acetyl-3-o-toluyl-5-fluorouracil
T10013
Synonym: A-​OT-​Fu
Target: Others
Floxuridine
T0964
Synonym: 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640
Target: Apoptosis, Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis, Antibacterial, HSV
Fosifloxuridine nafalbenamide
T33762
Synonym: NUC-3373,NUC3373,NUC 3373
Target: DNA/RNA Synthesis
Carmofur
T1307
Synonym: HCFU
Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis
5-Fluorouracil-1-yl  acetic acid
TNU1053
Synonym:
Target:
1-(b-D-Xylofuranosyl)-5-fluorouracil
TNU1481
Synonym:
Target:
5-Fluorouracil-1-yl  acetic acid methyl ester
TNU1052
Synonym:
Target:
5-Fluorouridine
T1349
Synonym:
Target: Others, DNA/RNA Synthesis
Emitefur
T27259
Synonym: BOFA2,BOF A2,BOF-A2
Target: Others
Doxifluridine
T1600
Synonym: Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Capecitabine
T1408
Synonym: Xeloda,Capecitibine,Capiibine,RO 09-1978
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
ZX-J-19J
T9936
Synonym: N-(2,3-Diphenyl-6-quinoxalinyl)octanamide
Target: Others
Edoxudine
T4374
Synonym: Aedurid,EUDR,Epoxudine
Target: Antiviral, Antibacterial
Uridine triacetate
T21327
Synonym: RG 2133 triacetate,PN-401,Tri-O-acetyluridine,PN401,RG 2133,RG-2133,PN 401,RG2133,RG2133 triacetate
Target: Others
Sparfosate sodium
T28831
Synonym: CI882,CI-882,CI 882
Target:
Nitrocaphane
T33686
Synonym: AT 1258,AT-1258,AT1258
Target:
FOLFIRI Regimen
T31837
Synonym: FOLFIRI
Target:
Benzylacyclouridine
T40932
Synonym: 5-Benzylacyclouridine,BAU
Target:
Bis-Pro-5FU
T72991
Synonym:
Target:
D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
T74046
Synonym:
Target:
(E)-5-(2-Bromovinyl)uracil
T35439
Synonym:
Target:
Ivaltinostat formic
T63074
Synonym:
Target:
Ansatrienin A
T36385
Synonym:
Target:
Ansatrienin B
T36650
Synonym:
Target:
4-(3,4-Difluorobenzo)curcumin
T83881
Synonym: CDF
Target:
DSPE-PEG(2000)-amine (sodium salt)
T36424
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T4720 6-Hydroxypyridin-2(1H)-one hydrochloride 2,6-Dihydroxypyridine hydrochloride Others , Endogenous Metabolite
6-Hydroxypyridin-2(1H)-one hydrochloride (2,6-Dihydroxypyridine hydrochloride) is used as a reagent to synthesize uridine phosphorylase inhibitors that increase Uridine (Urd) (U829910) levels. Uridine is a promising bioc...
T4919 Ureidopropionic acid Carbamoyl-b-alanine,3-Ureidopropionic acid Endogenous Metabolite
Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further de...
T4S1551 Cinnamaldehyde Cinnamic Aldehyde HIF
1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...
TN3152 6-Acetonyldihydrochelerythrine ERK , BCL , Akt , HIV Protease , PPAR , p53
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively...

Natural Products

6-Hydroxypyridin-2(1H)-one hydrochloride
T4720
Synonym: 2,6-Dihydroxypyridine hydrochloride
Target: Others, Endogenous Metabolite
Ureidopropionic acid
T4919
Synonym: Carbamoyl-b-alanine,3-Ureidopropionic acid
Target: Endogenous Metabolite
Cinnamaldehyde
T4S1551
Synonym: Cinnamic Aldehyde
Target: HIF
6-Acetonyldihydrochelerythrine
TN3152
Synonym:
Target: ERK, BCL, Akt, HIV Protease, PPAR, p53

Recombinant Proteins

Species：
Human (10)
E. coli (1)
Expression System：
HEK293 (9)
E. coli (2)
Tag：
hFc (4)
C-His-Avi (2)
His (2)
N-6His (1)
N-terminal 6xHis-SUMO-tagged (1)
mFc (1)
Cat No. Product Name Species Expression System
TMPH-00607 Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
Catalyzes the hydrolytic deamination of cytosine to uracil. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis. Is also able to catalyze deaminati...
TMPY-03048 PRAP1 Protein, Human, Recombinant (mFc) Human HEK293
PRAP1 is a protein interacting partner of MAD1 and that PRAP1 is able to down-regulate MAD1 and suppress mitotic checkpoint signalling in HCC. PRAP1 is a novel p53 target gene. The induction of PRAP1 expression by p53 ma...
TMPY-03076 PRAP1 Protein, Human, Recombinant (His) Human HEK293
PRAP1 is a protein interacting partner of MAD1 and that PRAP1 is able to down-regulate MAD1 and suppress mitotic checkpoint signalling in HCC. PRAP1 is a novel p53 target gene. The induction of PRAP1 expression by p53 ma...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00854 ETS1 Protein, Human, Recombinant (His) Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc) Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc) Human HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc) Human HEK293
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPK-01363 SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357 SIRP alpha V5 Protein, Human, Recombinant (His & Avi) Human HEK293
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
Cat No. Product Name
L5100 Fluorochemical Library

583 compounds
A unique collection of 583 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS);

Libraries

Fluorochemical Library
L5100
Compounds: 583
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