5omeudp trisodium salt

Potent P2Y6 agonist

Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.

Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.

Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.

Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chromosome fragmentation.

Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is involved in nucleic acid metabolism. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

5'-Guanylic acid disodium salt (GMP-5) is a purine ribonucleoside monophosphate. L-Glutamic acid and guanosine monophosphate are biosynthesized from xanthylic acid and L-glutamine via GMP synthase [glutamine-hydrolyzing]. Guanosine triphosphate and guanosine monophosphate are biosynthesized from diguanosine tetraphosphate via bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin, telithromycin, tobramycin, and erythromycin action pathways, and several metabolic disorders including AICA-ribosiduria, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and 2-hydroxyglutric aciduria (D and L form) pathways. Guanosine monophosphate is also found in foods like onion-family vegetables, millet, Chinese water chestnut, and red rice, serving as a potential biomarker for the consumption of these foods.

Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucleotides on growth of specific intestinal bacteria.

Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM) and can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.

Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.

Cytidine 5'-diphosphate trisodium salt (CDP) catalyzes the production of Cytidine triphosphate (CTP) for DNA and RNA synthesis by transferring a phosphoryl group from ATP to cytidine monophosphate (CMP) through the action of uridine monophosphate kinase (UMPK).

Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.

Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt), or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis.

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a nontoxic inhibitor of CMV replication, as well as a useful antidote in cases of acute cadmium intoxication.

Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates signal-transducing G proteins involved in cellular processes such as proliferation, differentiation, and activation of intracellular kinase cascades. It regulates proliferation and apoptosis through the hydrolysis by small GTPases Ras and Rho, and plays a role in vesicle docking, fusion, and formation via Rab. Additionally, GTP serves as an energy-rich precursor for the biosynthesis of DNA and RNA.

Ursulcholic acid trisodium salt (Ursodeoxycholic acid disulfate trisodium salt) is a soluble form of ursodeoxycholic acid which has antihyperlipidemia and gallbladder activity.

Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and inhibits migration and invasion of epithelial cancer cells.Foxy-5 Foxy-5 Ammonium Salt effectively reduces the metastatic spread of prostate cancer cells with low WNT5A expression in an in situ mouse model.

Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.

Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) serves as an intermediate in purine metabolism.

Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC).

2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription.

Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.

DL-Isocitric acid trisodium salt is the protonated form of isocitrate, a substrate in the citric acid cycle. It is useful as a marker for determining the composition of isocitrates in fruit products, including fruit juices.

Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and reverse transcriptase.

GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in most organisms.

Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms. Adenosine 5'-monophosphate disodium salt has been shown to have a variety of biochemical and physiological effects. It has been shown to increase cell metabolism, gene expression, and protein synthesis.

ARL-67156 trisodium salt hydrate is an ecto-ATPase inhibitor that prevents metabolism of P2 purinoceptor agonists.

N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator (Ka of 22 μM).

Uridine 5′-triphosphate tris salt (Uridine 5'-triphosphoric acid) is an agonist to the P2Y receptor and has been used to study concentrations of intracellular Ca2+, as well as a phosphate donor for in vitro kinase assays.

5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant hormones, alkaloids, and other secondary metabolites from glucose. Several phosphoribosyltransferases (PRTases) use PRPP as a substrate to add a 5-phosphoribosyl group to another substrate, as in the production of adenosine monophosphate from adenine and PRPP by adenine PRTase. N/A

ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.

Ribavirin 5'-monophosphate (lithium salt) directly inhibits IMP dehydrogenase (converts IMP to XMP).

Adenosine 5’-monophosphate triethylammonium salt is a useful organic compound for research related to life sciences and the catalog number is TNU1647.

Phthalamic acid, N-(5-(p-aminophenoxy)pentyl)-, lithium salt is a bioactive chemical.

2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium salt is a Nucleoside Triphosphate.

Nucleoside Derivatives - Phosphorus-containing nucleotides, Azido-nucleosides, 2’,3’-Dideoxy-nucleosides

2’-O-Methyl-N6-methyladenosine 5’-monophosphate triethylammonium salt (60091-05-6 neutral molecule) is a useful organic compound for research related to life sciences and the catalog number is TNU1630.

D-Fructose-1,6-diphosphate trisodium salt octahydrate is a useful organic compound for research related to life sciences and the catalog number is T65105.

Intermediates and Building Blocks - Nucleophile, Electrophile; Fine Chemical

PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki= 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein.1It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite.1The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235and Phe239form a sandwich-like structure with residue Phe10of PKI (5-24).2

2’-Deoxy-5-Fluorouridine 5’-phosphate triethyl ammonium salt is a valuable organic compound for life sciences research (catalog number TNU1203, CAS number 134-46-3).

Adenosine 3',5'-diphosphate sodium salt is an inhibitor of hydroxysteroid sulfotransferases, which are adenine nucleotides containing a phosphate group at the 3' and 5' positions of the pentose ribose.Adenosine 3',5'-diphosphate (sodium salt) is the product of 3'-phosphoadenosine 5'-phosphosulfonate (PAPS), a cofactor of sulfotransferases (SULTs). diphosphate disodium is the product of 3'-phosphoadenosine 5'-phosphosulfonate (PAPS), a cofactor for sulfotransferases (SULTs), which has been used to study the kinetic properties and structure of SULTs.

Uridine 5'-triphosphate tris salt is an endogenous metabolite.

Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can be used in the reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.

'3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II by competitively blocking UTP incorporation into RNA with a dissociation constant (Ki) of 2.0 μM[1].

Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.

5-BrUTP sodium salt is utilized to label RNA for the measurement of transcription.

N6-Methyladenosine 5’-monophos phate triethylammonium salt (neutral 4229-50-9) is a useful organic compound for research related to life sciences and the catalog number is TNU1631.

substrate of IMP dehydrogenase (IMPDH)

Oxidized ATP trisodium salt (oATP) is a broad-spectrum P2 receptor inhibitor that irreversibly antagonizes P2X7R activation and inhibits CRP-induced NLRP3 inflammasome activation, making it useful in atherosclerosis research [1] [2].