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Results for "
5oxoete
" in TargetMol Product Catalog- Inhibitors & Agonists2
5-OxoETE
T37303106154-18-1In house
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.[1] It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM.[2] 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils via a specific G protein-coupled receptor.[3],[4],[5],[6]
- $80
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5-OxoETE methyl ester
T3730474785-00-5
5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE . 5-OxoETE methyl ester is an agonist of oxoeicosanoid receptor 1 (OXER1; EC50 = 1.54 μM for β-arrestin recruitment) that has a higher maximal response than 5-oxoETE in a β-arrestin assay.
- $235
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