3-hydroxy agomelatine d3

3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).

3-O-Methyldopa-d3 is a deuterated compound of 3-O-Methyldopa. 3-O-Methyldopa has a CAS number of 300-48-1.

3-phenylpropionic acid-d5 is a deuterated compound of 3-phenylpropionic acid.

4,6-Dichloro-N-(methyl-d3)-3-pyridazinecarboxamide is a deuterated compound of 4,6-Dichloro-N-(methyl)-3-pyridazinecarboxamide. 4,6-Dichloro-N-(methyl)-3-pyridazinecarboxamide has a CAS number of 1609394-78-6.

trans-Hydroxy Loxoprofen-13C-d3 (Mixture of Diastereomers) the 13C and deuterated compound of trans-Hydroxy Loxoprofen. trans-Hydroxy Loxoprofen has a CAS number of 371753-19-4.

Estrone-d4 3-Sulfate Sodium Salt is a deuterated compound of Estrone 3-Sulfate Sodium Salt. Estrone 3-Sulfate Sodium Salt has a CAS number of 438-67-5.

Indole-2,4,5,6,7-d5-3-acetic-2,2-d2 Acid is a deuterated compound of Indole-3-acetic Acid. Indole-3-acetic Acid has a CAS number of 87-51-4. 3-Indoleacetic acid (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.

Indole-3-butyric acid-d2 is a deuterated compound of Indole-3-butyric acid. Indole-3-butyric acid has a CAS number of 133-32-4. 3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.

1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE serves as an internal standard for quantifying 1-palmitoyl-2-hydroxy-sn-glycero-3-PE, a lysophospholipid naturally found to inhibit L. donovani promastigotes growth (GI50= 8 µM). Its levels are reduced in mice after alcohol-induced liver damage, in hepatocellular carcinoma mouse xenografts, and in humans following a rigorous three-day exercise regimen of 2.5 hours running daily and 14 hours post-regimen. This compound is also applied in measuring saturated lysophosphoethanolamines, highlighting its broad utility in biochemical research and disease model studies.

25-Hydroxy vitamin D2-d3 is a deuterated compound of 25-Hydroxy vitamin D2.

3-phenylpropanoic-2,2-d2 acid is a deuterated compound of 3-phenylpropanoic-2,2 acid.

5-Hydroxyindole-3-acetic Acid-d6 is a deuterated compound of 5-Hydroxyindole-3-acetic Acid. 5-Hydroxyindole-3-acetic Acid has a CAS number of 54-16-0. 5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels of these substances may be measured in the urine to test for carcinoid tumors (NCI).

3-Methyl-2-quinoxalinecarboxylic Acid-d4 is a deuterated compound of 3-Methyl-2-quinoxalinecarboxylic Acid. 3-Methyl-2-quinoxalinecarboxylic Acid has a CAS number of 74003-63-7. 3-Methyl-2-quinoxalinecarboxylic acid has a wide range of applications in life science related research.

5-Hydroxy-L-tryptophan-4,6,7-d3 is a deuterated compound of 5-Hydroxy-L-tryptophan. 5-Hydroxy-L-tryptophan has a CAS number of 314062-44-7.

Methyl Indole-2,4,5,6,7-d5-3-acetate is a deuterated compound of Methyl Indole-2,4,5,6,7-3-acetate.

Indole-2,4,5,6,7-d5-3-acetic Acid is a deuterated compound of Indole-3-acetic Acid. Indole-3-acetic Acid has a CAS number of 87-51-4. 3-Indoleacetic acid (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.

1-1(Z)-Hexadecenyl-2-palmitoyl-d9-sn-glycero-3-PE serves as an internal standard for quantitating 1-1(Z)-hexadecenyl-2-palmitoyl-sn-glycero-3-PE, which is a plasmalogen incorporating 1(Z)-hexadecanoic acid and palmitic acid at the sn-1 and sn-2 positions respectively, in analyses performed using GC- or LC-MS.

1-[3-carboxypropyl]-3,7-dimethylxanthine-d6 is a deuterated compound of 1-[3-carboxypropyl]-3,7-dimethylxanthine.

3 Hydroxy Midostaurin Epimer 1-d5 is a deuterated compound of 3 Hydroxy Midostaurin Epimer 1. 3 Hydroxy Midostaurin Epimer 1 has a CAS number of 945260-14-0.

25-Hydroxy vitamin D3-d3 is a deuterated compound of 25-Hydroxy vitamin D3.

Hydroxy Dimetridazole-d3 is a deuterated compound of Hydroxy Dimetridazole. Hydroxy Dimetridazole has a CAS number of 936-05-0. Hydroxy Dimetridazole is a hydroxy metabolite of Dimetridazole which combats protozoan infections.

rac 1,2-Bis-palmitoyl-3-chloropropanediol-d5 is a deuterated compound of rac 1,2-Bis-palmitoyl-3-chloropropanediol. rac 1,2-Bis-palmitoyl-3-chloropropanediol has a CAS number of 51930-97-3. rac-1,2-bis-Palmitoyl-3-chloropropanediol is a 3-monochloropropane-1,2-diol (3-MCPD) ester.1It has been found as a contaminant in edible olive oils, with the lowest and highest concentrations in extra virgin and olive pomace oils, respectively.rac-1,2-bis-Palmitoyl-3-chloropropanediol has also been found in cottonseed and palm oils, as well as in shortening.2It induces renal tubular necrosis and a decrease in spermatids, but no gross pathological changes, in mice.3

3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for treatment of P

Hydroxy Ipronidazole-d3 is a deuterated compound of Hydroxy Ipronidazole. Hydroxy Ipronidazole has a CAS number of 35175-14-5. L 12407 is an antiprotozoal drug of the nitroimidazole class. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.

3-Keto Fenretinide-d4 is a deuterated compound of 3-Keto Fenretinide. 3-Keto Fenretinide has a CAS number of 865536-65-8. 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.

3-Methyl-d3-butyric-3,4,4,4-d4 Acid is a deuterated compound of 3-Methyl-butyric Acid. 3-Methyl-butyric Acid has a CAS number of 503-74-2. 3-Methylbutanoic acid is a naturally occurring aroma compound found in Bartlett pear brandies, vanilla beans, rape-honey, and banana.

3-Methoxy Dopamine-d4 Hydrochloride is a deuterated compound of 3-Methoxy Dopamine Hydrochloride.

3-(4-Hydroxyphenyl)propionic acid-d4 is a deuterated compound of 3-(4-Hydroxyphenyl)propionic acid. 3-(4-Hydroxyphenyl)propionic acid has a CAS number of 501-97-3. Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA (1-palmitoyl-d9LPA) serves as an internal standard for the quantification of 1-palmitoyl LPA using GC- or LC-MS. This compound, an analog of LPA with palmitic acid at the sn-1 position, activates reporter gene expression in PC12 cells fitted with human lysophosphatidic acid receptor 4 (LPA4) at 0.01 to 10 µM concentrations. Additionally, 1-palmitoyl LPA prompts aggregation in isolated human platelets within the 12-300 µM range, a process reversible by prostaglandin E1 (PGE1), theophylline, or EDTA. It also interacts with calcium and magnesium to boost the efficacy of ampicillin, piperacillin, and ceftazidime against P. aeruginosa strains from cystic fibrosis patients.

3-Hydroxy Repaglinide-d5 is a deuterated compound of 3-Hydroxy Repaglinide.

DL-4-Hydroxy-3-methoxymandelic-d3 acid is a deuterated compound of DL-4-Hydroxy-3-methoxymandelic acid.

3-Chloro-1,2-Propanediol-d5 is a deuterated compound of 3-Chloro-1,2-Propanediol. 3-Chloro-1,2-Propanediol has a CAS number of 96-24-2.

3-Nitrofluoranthene-d9 is a deuterated compound of 3-Nitrofluoranthene. 3-Nitrofluoranthene has a CAS number of 892-21-7.

3-Butylphthalide-d9 is a deuterated compound of 3-Butylphthalide. 3-Butylphthalide has a CAS number of 6066-49-5. Butylphthalide is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn.

7-Desmethyl-agomelatine D3 is a deuterium labeled 7-Desmethyl-agomelatine. 7-Desmethyl-agomelatine is a metabolite of Agomelatine.

3 Hydroxy Midostaurin Epimer 2-d5 is a deuterated compound of 3 Hydroxy Midostaurin Epimer 2.3 Hydroxy Midostaurin Epimer 2 has a CAS number of 155848-20-7.

3-Indoleacrylic acid-d4 is a deuterated compound of 3-Indoleacrylic acid. 3-Indoleacrylic acid has a CAS number of 1204-06-4. 3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by immune cells.

Netupitant N-oxide (3)-d6 is a deuterated compound of Netupitant N-oxide (3). Netupitant N-oxide (3) has a CAS number of 910808-11-6.

5-Hydroxy tryptophol β-D glucuronide-d4 is a deuterated compound of 5-Hydroxy tryptophol β-D glucuronide.

1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE serves as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) using GC- or LC-MS. 1,2-DPPE, a prevalent PE (phospholipid), contains C16:0 fatty acids at the sn-1 and sn-2 positions and is essential in the inner plasma membrane leaflet. This compound forms a condensed lipid monolayer with cholesterol through tight hydrogen bonding between 1,2-DPPE headgroups, enhancing membrane fluidity to support transport and signaling.

Indole-3-Acetic-d2 Acid is a deuterated compound of Indole-3-Acetic Acid. Indole-3-Acetic Acid has a CAS number of 87-51-4. 3-Indoleacetic acid (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.

Pyridin-3-ylmethanamine-d2 is a deuterated compound of Pyridin-3-ylmethanamine. Pyridin-3-ylmethanamine has a CAS number of 3731-52-0. Picolamine acts as a potential inhibitor of DPP-4.

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation of glycosphingolipid antigens into DPPC-containing liposomes increases the immunogenicity of the antigens in mice.4 |1. Ege, C., and Lee, K.Y.C. Insertion of Alzheimer's Aβ40 peptide into lipid monolayers. Biophys. J. 87(3), 1732-1740 (2004).|2. Leekumjorn, S., and Sum, A.K. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys. J. 90(11), 3951-3965 (2006).|3. Kalra, V.K., Sikka, S.C., and Sethi, G.S. Transport of amino acids in γ-glutamyl transpeptidase-implanted human erythrocytes. J. Biol. Chem. 256(11), 5567-5571 (1981).|4. Uemura, A., Watarai, S., Iwasaki, T., et al. Induction of immune responses against glycosphingolipid antigens: Comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J. Vet. Med. Sci. 67(12), 1197-1201 (2005).

3-Acetyldeoxy nivalenol-13C17is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found inF. graminearum.1In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50= 70 mg/kg) in mice.2 1.Jiao, F., Kawakami, A., and Nakajima, T.Effects of different carbon sources on trichothecene production and Tri gene expression by Fusarium graminearum in liquid cultureFEMS Microbiol.Lett.285(2)212-219(2008) 2.Schiefer, H.B., Nicholson, S., Kasali, O.B., et al.Pathology of acute 3-acetyldeoxynivalenol toxicity in miceCan. J. Comp. Med.49(3)315-318(1985)

rac 1-Palmitoyl-3-Chloropropanediol-d5 is a deuterated compound of rac 1-Palmitoyl-3-Chloropropanediol. rac 1-Palmitoyl-3-Chloropropanediol has a CAS number of 30557-04-1.

2,4-D-d3 is a deuterated compound of 2,4-D. 2,4-D has a CAS number of 94-75-7. 2,4-Dichlorophenoxyacetic acid is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the actin cytoskeleton for the control of root elongation and cell production.

3-Amino-2-Oxazolidinone-d4 is a deuterated compound of 3-Amino-2-Oxazolidinone. 3-Amino-2-Oxazolidinone has a CAS number of 80-65-9. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone. It is always be detected as a indicator of furazolidone residues in vivo.

(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid is a deuterated compound of (4-Hydroxy-3-methoxyphenyl)acetic Acid. (4-Hydroxy-3-methoxyphenyl)acetic Acid has a CAS number of 306-08-1. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.