2' deoxyadenosine

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity for cancer research.

2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-triphosphate (dATP) is a substrate for DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate (dATP) is an inhibitor of RNA through an inactive alpha4beta4 quaternary structure. Deoxyadenosine-5'-triphosphate inhibits RNA through the inactive α4beta4 quaternary structure.2'-Deoxyadenosine-5'-triphosphate has been associated with cardiomyocyte growth.

2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA.

2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthesis or replication.

N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.

5'-O-DMTr-N6-ethyl-2'-deoxyadenosine 3'-CED phosphoramidite is a Nucleoside Phosphoramidite.

2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis.

2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.

2-Bromo-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2-Modified purine nucleoside; Scaffold and Template.

2'-Deoxyadenosine-5'-monophosphate (D-AMP) is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic acid ATP, or adenosine triphosphate, in which the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose has been removed (hence the deoxy- part of the name). Additionally, the monophosphate of the name indicates that two of the phosphoryl groups of GTP have been removed, most likely by hydrolysis. Deoxyadenosine monophosphate is abbreviated dAMP.

Deoxyadenosine, a deoxyribonucleoside, is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety.

3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group open.

2-Iodo-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2-Modified purine nucleoside; Scaffold and Template.

2'-Chloro-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2'-Modified nucleoside.

2-Chloro-N6,N6-dimethyl-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside, 2-Modified purine nucleoside, 6-Modified purine nucleoside.

N6-Isopentenyl-2'-deoxyadenosine is a Nucleoside Derivative - 6-Modified purine nucleoside.

3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM. This nucleoside can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function.

8-Chloro-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside, 8-Modified purine nucleoside.

2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.

2-Methyl-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.

8-Bromo-2'-deoxyadenosine is a 2'-Deoxynucleoside; Halo-nucleoside.

8-Methyl-2'-deoxyadenosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

2-Methoxy-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.

2-Chloro-N6-methyl-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside, 2-Modified purine nucleoside, 6-Modified purine nucleoside.

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine is a useful organic compound for research related to life sciences. The catalog number is T66118 and the CAS number is 64325-78-6.

N6-Benzoyl-2'-chloro-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2'-Modified nucleoside.

2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.5 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Key steps in nucleotide biosynthesis are regulated by feedback inhibitionBiochemistry(2002) 2.Berg, J.M., Tymoczko, J.L., and Stryer, L.DNA is replicated by polymerases that take instructions from templatesBiochemistry(2002) 3.Cadwell, R.C., and Joyce, G.F.Randomization of genes by PCR mutagenesisPCR Methods Appl.2(1)28-33(1992) 4.Steffens, D.L., Jang, G.Y., Sutter, S.L., et al.An infrared fluorescent dATP for labeling DNAGenome Res.5(4)393-399(1995) 5.Flinn, A.M., and Gennery, A.R.Adenosine deaminase deficiency: A reviewOrphanet J. Rare Dis.13(1)65(2018)

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) is a nucleoside reverse transcriptase (RT) inhibitor. It is potent against drug-resistant HIV variants (EC50: 98 nM in MT-4 cells for anti-HIV-1 activity).

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group open.

Nucleoside Derivatives - 8-Aza-7-deaza-purine nucleoside

Nucleoside Derivatives - 6-Modified purine nucleosides,

Nucleoside Derivatives - Halo-nucleoside; 2’-Modified nucleoside, Protected nucleosides with NH2/OH open

Nucleoside Derivatives - 6-Modified purine nucleosides, Protected nucleosides with NH2/OH open

Nucleoside Derivatives - N-Methylated/ alkylated nucleosides; DNA adduct

Nucleoside Derivatives - 8-Modified purine nucleosides; Azido nucleosides

Nucleoside Derivatives - 3’-Deoxy nucleosides, Halo-nucleosides, 2-Modified purine nucleosides; Scaffolds and Templates

Nucleoside Derivatives - 3’-Modifed nucleosides, Protected nucleosides with NH2/OH group open; Used for conjugation

Nucleoside Derivatives - 8-Modified purine nucleosides; Amino nucleosides

Nucleoside Derivatives - Protected nucleosides with NH2/OH open; 3’-Modifed nucleosides; Used for conjugation

Nucleoside Derivatives –7-Deaza-purine nucleosides; Drugs and Inhibitors; Purine nucleoside phosphorylase inhibitor

Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.

2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling.

dADP disodium (2'-Deoxyadenosine 5'-di-phos-phate disodium) is widely found in plants and animals, competitively inhibits bacterial poly(A) polymerase, and is involved in the body's energy cycle.

Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides

Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of 2'-deoxyadenosine and adenosine to 2'-deoxyinosine and inosine, respectively.

5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis. The normal form of deoxyadenosine used in DNA synthesis and repair is 2'-deoxyadenosine where the hydroxyl group (-OH) is at the 2' position of its ribose sugar moiety. 5'-deoxyadenosine has its hydroxyl group at the 5' position of the ribose sugar.