2-chloro palmitic acid

2-chloro Palmitic acid is a monochlorinated form of palmitic acid . It is produced in a myeloperoxidase (MPO) and time-dependent manner in neutrophils stimulated by phorbol 12-myristate 13-acetate . 2-chloro Palmitic acid (10 μM) induces neutrophil extracellular trap (NET) formation (NETosis) in human neutrophils, increasing DNA release from neutrophils, colocalization of MPO with extracellular DNA (ecDNA), and trapping of E. coli. It increases COX-2 protein levels in human coronary artery endothelial cells (HCAECs) when used at a concentration of 50 μM and increases production of P-selectin, von Willebrand factor, and angiopoietin-2 in HCAECs, as well as neutrophil and platelet adherence, when used at a concentration of 10 μM. 2-chloro Palmitic acid (10-50 μM) also induces apoptosis in THP-1 cells and primary human monocytes and increases caspase-3 activity in THP-1 cells.

Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorders The urinary excretion of Trans-2-butene-1,4-dicarboxylic acid is increased in conditions of augmented mobilization of fatty acids or inhibited fatty acid oxidation.

2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25.

4-Chloro-3-nitrobenzoic acid is a nitric oxide scavenger and has been used to study the effects of nitric oxide on the cardiovascular system and the effects of nitric oxide on the immune system.

2-Acetylbenzoic acid is more potent than 2-propionyloxybenzoic acid in inhibiting platelet function and platelet prostaglandin (PG) synthesis although the potencies of these agents were comparable in inhibiting prostacyclin (PGI2) synthesis.

2-Iodobenzoic acid (o-Iodobenzoic acid) is the impact-sensitive intermediate in the synthesis of the Dess-Martin periodinane.

Compound Fr12564 is a useful organic compound for research related to life sciences. The catalog number is Fr12564 and the CAS number is 3438-16-2.

2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid can be used to synthesize a variety of organic compounds.

2-(4-Methoxyphenyl)acetic acid, a plasma metabolite, is highly sensitive and specific and can be used as a bioindicator to differentiate non-small cell carcinoma patients from healthy controls.

2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid can reduce serum cholesterol and triglyceride levels and has anti-lipidemic effects.

2-Hydroxyhexanoic acid (2-Hydroxycaproic acid) is a branched-chain alpha-keto acid that has been reported in normal human blood and in normal amniotic fluid. It has been found that 2-Hydroxyhexanoic acid is the most significant metabolite found in the CSF of patients infected with Nocardia.

2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease.

2-Methylhexanoic acid is a flavouring ingredient.

Compound Fr12622 is a useful organic compound for research related to life sciences. The catalog number is Fr12622 and the CAS number is 79047-41-9.

L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.

2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.

(2-Aminoethyl)phosphonic acid (2-Aminoethylphosphonic acid) is primarily detected in urine. (2-Aminoethyl)phosphonic acid participates in many enzymatic reactions and is also the parent compound of other transformation products, including but not limited to ceramide 2-(methylamino)ethylphosphonate, N-(2-phosphineethyl)cholamide and CMP-2-aminoethylphosphonate.

(2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid is a chemical synthesis intermediate.

(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.

2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid is commonly used to synthesize compounds with anticancer and antitumor properties.

1H-Pyrrole-2-carboxylic acid, 4,5-dibromo-1-methyl- (1-methyl-4,5-dibromopyrrole-2-carboxylic acid) is a marine derived natural products found in Agelas flabelliformis.

2-Chloro-4-nitrophenol is a phenolic compound. It is an inhibitor of cyclooxygenase (COX), which reduces the production of prostaglandins, thereby reducing inflammation and pain.

1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl] is an antifibrotic agent.

N-(4-bromo-2-chlorophenyl)-5-chloro-2-hydroxybenzamide is a benzamide analog with anti-tumor, anti-inflammatory, anti-bacterial and anti-fungal activities.

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.

2-Chlorophenylboronic acid is a monohalogenated phenylboronic acid, which is an important pharmaceutical intermediate and is widely used in the synthesis of new drugs.2-Chlorophenylboronic acid has an inhibitory effect on fatty acid amidase with a Ki value of 0.01-1 µM, and is used in the study of depression, glaucoma, neuropathic pain, anxiety, migraine, I diabetes and gastritis. , migraine, type I diabetes and gastritis.

N-[1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]benzamide is a racemic form of Cl-amidine (S enantiomer). Cl-amidine is an orally active peptidylarginine deminase (PAD) inhibitor.

Ipamorelin 2 Pivalic acid (NNC-26-0161) is a growth-hormone-releasing peptide, induces longitudinal bone growth in rats.

5-Chloroanthranilic Acid is a metabolite of the pesticide Chlordimeform. It can be used in the preparation of disease-modifying antirheumatic drugs (DMARDs).

4,5-Dibromo-1H-Pyrrole-2-Carboxylic Acid (4,5-Dibromo-2-pyrrolic acid) is a marine derived natural products found in Agelas oroides.

(4R)-3-[2-(4-chlorophenoxy)-2-methylpropanoyl]-1,3-thiazolidine-4-carboxylic acid can be used in research in the fields of chemistry and life sciences.

4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid is used as a pharmaceutical intermediate.

4-Amino-5-Chloro-2-Methoxybenzoic Acid (Metoclopramide EP Impurity C) is a Metoclopramide metabolite.

3-Methyl-2-nitrobenzoic acid is in agricultural chemicals such asWithPreparation in be used as intermediate.

2-Methyl-2H-indazole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is Fr21265 and the CAS number is 34252-44-3.

L-2-Phosphoglyceric acid (L-2-Phosphoglyceric acid disodium salt) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate.

DL-2-AMINOOCTANOIC ACID, also known as α-aminooctanoic acid or α-aminooctanoic acid, can be used as a modifier to modify Na-MMT clay.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

Compound Fr13623 is a useful organic compound for research related to life sciences. The catalog number is Fr13623 and the CAS number is 496-41-3.

6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a compound used as a molecular structural unit for pefloxacin impurities.

2-CHLORO-5-CYANOPYRAZINE (5-Chloropyrazine-2-carbonitrile) is an active biochemical.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.

1-[(5-chlorothiophen-2-yl)sulfonyl]pyrrolidine-2-carboxylic acid has been used as a starting material for the synthesis of drugs, polymers, etc., and has also been used to synthesize bioactive compounds such as peptides, peptoids, and Other small molecules.

2-(3,5-dibromo-4-methoxyphenyl)acetic acid (3,5-Dibromo-4-methoxyphenyl acetic acid) is a marine derived natural products found in Ianthella quadrangulata.

2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid belonging to the pyrimidine family, which has been shown to have anti-inflammatory, anticonvulsant and antitumor properties.

2-(Acetyloxy)-3-Methylbenzoic Acid is used in qHTS Assay for Inhibitors of hydroxysteroid (17-beta) dehydrogenase 4, HSD17B4 with activity value of 19.95 μM

α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid was identified as possible dual inhibitors for hLTA4H and hLTC4S enzymes by the computer-aided methodology.