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Inhibitors & Agonists

2-fluoroadenine

" in TargetMol Product Catalog

Inhibitors & Agonists
2

2-Fluoroadenine

T20038700-49-2

2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.

DNA/RNA Synthesis

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2'-Fluoro-2'-Deoxyadenosine

T972764183-27-3

2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA.

Nucleoside Antimetabolite/Analog

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