1-hydroxymethyl-b-carboline glucoside

AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic.

Dynorphin B (1-13) acetate acts as an agonist on opioid κ-receptor.

b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 μM and an E.max value of > 250 μM for TREM2.

MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.

1-Methoxycarbonyl-β-carboline (1-Methoxycarbonyl-beta-carboline) is an alkaloid from Ailanthus altissima.

Isopentyl b-D-glucoside is a useful organic compound for research related to life sciences. The catalog number is T126225 and the CAS number is 120671-07-0.

Torachrysone-8-O-b-D-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.

CR-1-31-B, a synthetic rocaglate, acts as a highly potent inhibitor of eIF4A. By disrupting the interaction between eIF4A and RNA, it effectively obstructs the initiation phase of protein synthesis. Specifically, CR-1-31-B interferes with the association between Plasmodium falciparum eIF4A (PfeIF4A) and RNA. Additionally, CR-1-31-B induces apoptosis in neuroblastoma and gallbladder cancer cells [4].

Blumenol B 9-O-glucoside is a natural product for research related to life sciences. The catalog number is TN6251 and the CAS number is 114226-08-3.

Scillascilloside B-1 is a natural product from Scilla scilloides.

Cucurbitacin B 2-o-α²-D-glucoside has anticancer activity.

1-Methoxycarbonyl-beta-carboline-N-oxide is a natural product for research related to life sciences. The catalog number is TN6652 and the CAS number is 74690-74-7.

Factor B-IN-1 is a Factor B inhibitor.

1-Methoxymethyl-β-carboline, a natural product, has been isolated from the root of Eurycoma longifolia [1].

1-(3,4,5-Trihydroxypentanoyl)-β-carboline is a natural product for research related to life sciences. The catalog number is TN6093 and the CAS number is 180995-40-8.

2,7-Dimethyl-1,4-dihydroxynaphthalene 1-O-glucoside is a natural product for research related to life sciences. The catalog number is TN2746 and the CAS number is 839711-70-5.

Cardenolide B-1 is a natural product of Nerium, Apocynaceae. The catalog number is TN3595 and the CAS number is 1318158-89-2. Cardenolide B-1 can be used as a reference standard.

Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside (compound 9), a steroidal saponin, is isolated from the variety yunnanensis of Paris polyphylla, commonly known as Yunnan pine [1].

Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA.

Bcl-B inhibitor 1 is a Bcl-B inhibitor with antitumor activity that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain.

1-Formyl-β-carboline is an alkaloid derived from the leaves of Ailanthus altissima.

Fraxiresinol 1-O-glucoside is a natural product from Ilex pubescens.

Tenacigenin B, a component of the plant Poria cocos, is identified as 3-O-β-Allopyranosyl-(1→4).

Beta-Carboline-1-propanoic acid is a reference standard compound, it is also a synthetic precursor compound. It is a derivative of indole and has been used in the synthesis of other indole derivatives such as indole-3-carboxaldehyde and as a starting material for the synthesis of polycyclic aromatic compounds. It has also been used to study the conformational relationships of indole-containing compounds and has been used as a model compound to study indole reactivity.

Quercetin-3-O-β-D-galactopyranosyl-(1→6)-β-D-glucopyranoside (compound 1), a flavonoid glycoside, is extractable from M. delavayi leaves [1].

'(Des-Bromo)-Neuropeptide B (1-23) (human)' is an agonist for orphan G-protein-coupled receptors, exhibiting a K i of 1.2 nM for GPR7 (NPBW1) and 341 nM for GPR8 (NPBW2) respectively [1].

1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside shows certain antibacterial activity.

Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2.

Plipastatin B 1 is a lipopeptide.

Dynorphin B (1-13), a 13 amino acid, is an extraordinarily potent opioid peptide.

Hydroxytyrosol 1-O-glucoside is a useful organic compound for research related to life sciences and the catalog number is T124248.

1-Hydroxymethyl-beta-carboline glucoside is a natural product from Picrasmae Ramulus et Folium.

3,4-Dihydro-4-[[2-hydroxy-1-(hydroxymethyl)ethoxy] methyl]-3-oxo-2-pyrazinecarboxamide is a Nucleoside Derivative - Acyclic nucleoside.

Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosides

PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.

8-Hydroxy-1-(hydroxymethyl)-3-methylxanthone is a useful organic compound for research related to life sciences. The catalog number is T124554 and the CAS number is 60883-98-9.

Nucleoside Derivatives - 7-Deaza-purine nucleosides; Natural product; inhibitor of protein kinase C

Nucleoside Derivatives - 8-Aza-7-deaza purine nucleosides, Halo-nucleosides

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65682 and the CAS number is 111974-74-4.

1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside; 8-Modified purine nucleoside; Amino nucleoside.

Quercetin 3-O-(6-O-malonyl)-b-D-glucoside is a useful organic compound for research related to life sciences. The catalog number is T123838 and the CAS number is 96862-01-0.

4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile is a useful organic compound for research related to life sciences. The catalog number is T67635 and the CAS number is 103146-25-4.

Nucleoside Derivatives - 7-Deaza-8-aza purine nucleosides; Halo-nucleosides; 6-Modified purine nucleosides

UT-B-IN-1 (UTBINH-14) is a reversible, competitive, and selective inhibitor of the urea transporter-B (UT-B), demonstrating IC50 values of 10 nM and 25 nM for human and mouse UT-B, respectively. It exhibits low toxicity and superior selectivity against UT-B compared to UT-A isoforms. This compound enhances urine production and decreases urine concentration in mice, making UT-B-IN-1 suitable for research on diuretic mechanisms.

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T66536 and the CAS number is 256376-65-5.

Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .

7-Hydroxy-beta-carboline-1-propionic acid is a useful organic compound for research related to life sciences and the catalog number is T125336.

Dual AChE-MAO B-IN-1 (compound 15) is a safe, metabolically stable neuroprotective agent.Dual AChE-MAO B-IN-1 is a potent, orally active CNS-permeable inhibitor of human AChE (IC50=550 nM) and MAO-B (IC50=8.2 nM), and has low in vitro activity against AChE and MAO-B with IC50 values of 550 nM, 8.2 nM respectively.